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Atopic disease is associated with chronic inflammation, and anemia has been reported in patients with inflammatory disorders such as rheumatoid arthritis, chronic obstructive pulmonary disease, and irritable bowel disease. The objective of this study was to determine whether atopic disease is associated with an increased risk of anemia. A cross-sectional study with propensity score weighting was conducted using a health insurance review agency claims dataset comprised of randomized patients who used the Korean national health system at least once in 2016. The association between atopic disease (asthma, atopic dermatitis, allergic rhinitis) and anemia (iron deficiency anemia (IDA) and/or anemia of inflammation (AI)) was examined. A total of 1,468,033 patients were included in this study. The IDA/AI prevalence was 3.1% (45,681 patients). After propensity score weighting, there were 46,958 and 45,681 patients in the non-anemic and anemic groups, respectively. The prevalence of IDA/AI in patients with atopic dermatitis, allergic rhinitis, or asthma had an odds ratio (OR) of 1.40 (95% confidence interval (CI), 1.33-1.48; p less then 0.001), 1.17 (95% CI, 1.14-1.21; p less then 0.001), and 1.32 (95% CI, 1.28-1.36; p less then 0.001), respectively. In addition, the prevalence of IDA increased with higher numbers of atopic diseases. In conclusion, the prevalence of IDA/AI was higher in patients with atopic disease, even after adjusting for demographic characteristics and other risk factors. Further study is needed to distinguish between IDA and AI and to enhance understanding of the etiology of anemia in patients with inflammatory conditions.Biological soil crusts, known also as biocrusts, provide valuable ecosystem services, especially in arid and semiarid regions. They may affect geomorphological (stability), hydrological (infiltration, evaporation), biochemical (carbon and nitrogen fixation) and ecological (germination and growth of vascular plants) processes, and their disturbance may have important ecological consequences. The common view, as reflected in hundreds of papers, regards biocrusts as having extremely slow recovery with characteristic time of up to hundreds and even thousands of years. Long recovery time implies that disturbance or climate change may have severe long-lasting consequences even once the conditions return to their initial state, triggering ample efforts to hasten biocrust recovery by inoculation. We critically analyze available estimates of the crust recovery time and present systematic measurements and theoretical considerations that attest to relatively rapid recovery of the crusts. We conclude that the likely recovery time of cyanobacterial crusts is 5-10 years, while that of lichen- and moss-dominated crusts is 10-20 years. Subsequently, costly and potentially negative effects to the ecosystem during inoculation should be weighed against the fast natural recovery of the biocrusts. Pargyline BACKGROUND Extreme heat events have been consistently associated with an increased risk of hospitalization for various hospital diagnoses. Classifying heat events is particularly relevant for identifying the criteria to activate early warning systems. Heat event classifications may also differ due to heterogeneity in climates among different geographic regions, which may occur at a small scale. Using local meteorological data, we identified heat waves and extreme heat events that were associated with the highest burden of excess hospitalizations within the County of San Diego and quantified discrepancies using county-level meteorological criteria. METHODS Eighteen event classifications were created using various combinations of temperature metric, percentile, and duration for both county-level and climate zone level meteorological data within San Diego County. Propensity score matching and Poisson regressions were utilized to ascertain the association between heat wave exposure and risk of hospitalization fordefine the set of criteria to activate early warnings systems and thus maximize public health benefits. V.Dynamic changes in soil organic carbon pools have significant impacts on regional and global carbon balance. Due to rapid development in urbanized areas, the land use changes dramatically, impacting soil organic carbon (SOC) stocks in topsoil. This study aimed to document the impacts of urbanization on SOC stocks in a rapidly urbanized area from northeastern China. A total of 12 auxiliary variables were as SOC predictors including elevation, slope aspect, slope gradient, topographic wetness index, Landsat TM band3, Landsat TM band4, Landsat TM5, and normalized difference vegetation index. Urban-specific variables including population (POP), gross domestic product (GDP), distance to the socio-economic center, and distance to the roads are also considered. A set of 523 (in 1990) and 847 (in 2015) top soil samples with SOC measurement were collected. Two random forest (RF) models, one with all auxiliary variables except urban-specific variable (MA) and the other with all auxiliary variables (MB) were used to map the spatial distribution of SOC stocks in the two periods. Ten-fold cross-validation was conducted to evaluate the performance of RF models. We find that the full auxiliary variables model had a better performance for the both periods. POP and GDP were key auxiliary variables affecting spatial variability of SOC stocks in 2015. Over a 25-year period, SOC stocks decreased from 2.77 ± 1.09 kg m-2 to 2.16 ± 0.93 kg m-2, resulting in 3.78 Tg SOC loss in this region. Rapid urbanization led to drastic land- use change, which was the main reason for the decrease of SOC stocks. Additionally, urban-specific variables should be used as the main auxiliary variables when predicting SOC stocks in the areas that experience rapid urbanization. We believe that accurate prediction and mapping of SOC stocks will help manage land use and facilitate soil quality assessment so as to increase soil carbon sequestration in the region. The objective of this study was to evaluate the fractionation of ZnO and CuO engineered nanoparticles (ENPs) in soils with a pH adjusted to 4.0, 6.5, and 9.0 after 1 day and 30 days of incubation. Based on the multi-stage extraction, 5 fractions of metals were determined. Moreover, the effect of ENPs on the activity of acid, neutral and alkaline phosphatase was determined. The results of the study revealed that pH had a dominant effect on the metal participation in soils. The levels of those fractions of metals differed between nano-ZnO and nano-CuO, which could have resulted from differences in the dissolution of the ENPs. After 1 day, the concentration of Zn2+ (0.02-7.4 mg L-1) was 10 times higher than that of Cu2+. The metal fractionation in soil treated with ENPs and metal salts may also confirm the role of ENP dissolution. The concentration of potentially bioavailable fraction of Zn increased with a drop in pH. At a 4 pH concentration of Zn in the treatment with nano-ZnO and ZnCl2 was at a similar level (42.

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