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eded. .Scab (caused by Venturia effusa) is the most important yield-limiting disease of pecan in the southeastern USA. On susceptible cultivars, the disease is managed using fungicides, but spray coverage is an issue in tall trees. In four experiments we used an air-blast sprayer to compare scab severity on fruit at 5.0 to 15.0 m height in trees receiving the same dose of fungicide at 468, 935 and 1871 L/ha at 2.4 and 3.2 km/h (in two additional experiments fungicides were applied at 4.0 km/h @ 470 L/Ha, 4.0 km/h @ 940 L/Ha and 4.0 km/h @ 1100 L/Ha). An air-blast sprayer was used for the applications, which included typical recommended active ingredients (a.i.). Nozzles were selected to provide similar proportions of spray to the upper and lower canopy. The treatments (or subsets thereof) were repeated in 2015 to 2017 on cv. Schley, and in 2017, 2019 and 2020 on cv. Desirable. All treatments reduced scab compared to the control. Overall, there was no consistent difference among the treatments for severity of scab on foliage, immature fruit, or mature fruit at any height in the canopy up to 15.0 m (maximum height sampled). Fungicide applied at 2.4 or 3.2 km/h @ 470 L/ha was as effective at reducing disease as were the higher volumes (sometimes more so). The scab epidemic severity affected control efficacy. Estimated cost and water savings based on faster speed and lower volume were considerable. These preliminary observations indicate no single volume or speed was consistently superior to control scab; this suggests in most seasons, low volumes (higher concentration of a.i.) may be similarly efficacious as high volumes (lower concentration of a.i.) for controlling scab in tall pecan trees, and offer greater resource use efficiency.Soybean dwarf virus (SbDV, genus Luteovirus) is a single-stranded positive-sense RNA virus able to infect several legume species. SbDV was first reported in Japan where it was associated with significant yield losses in soybean (Tamada, 1969). Since then the virus has been detected worldwide. In Europe, the virus has only been reported from Germany (Abraham et al. 2007; Gaafar et al. 2020). In July 2018, several white clover plants (Trifolium repens L.) with leaf discoloration were observed in different locations in Oulu region in northern Finland. Individual plants were collected and analysed for the presence of viruses using small-RNA (sRNA) sequencing (Kreuze et. al. 2009) and reverse transcription-PCR (RT-PCR). Total RNA was extracted using EZNA micro RNA kit (Omega Bio-Tek, GA, USA). For sRNA analysis, sequencing libraries were constructed using the TruSeq small RNA library prep kit (Illumina, CA, USA) and sequenced on Illumina MiSeq platform. On average, 1.3 million single-end reads were obtained per sahave only been reported on soybean (Tamada, 1969), the virus also causes symptoms in other legume crops, such as growth reduction on pea (Tian et al. 2017) and faba bean (Abraham et al. 2007), both of which are cultivated in Finland. References Abraham et al. 2007. Plant Dis. 91 1059. Gaafar et al. 2020. Front microbiol. 11 583242. Kreuze et al. 2009. Virology 3881. Schneider et al. 2011. Virology 412 46. Tamada. 1969. Ann Phytopathol Soc Jpn. 35 282. Terauchi et al. 2003. Phytopathology 93 1560. Tian et al. 2017. Viruses 9 155. Zheng et al. 2017. Virology 500 130.Bleach products containing hypochlorite are commonly used as disinfestants to eliminate non-fungal plant pathogens from production surfaces, tools, plant surfaces, irrigation water, and produce dump tanks. While bleach products are useful, their effectiveness has been reported to vary under specific settings. A meta-analysis was conducted using 86 studies to assess the overall efficacy of hypochlorite against plant pathogenic bacteria, oomycetes and viruses and to identify factors that explain differences in product efficacy. Hypochlorite resulted in a significant (P less then 0.0001) reduction in either disease intensity or propagule viability with a mean Hedges' g standardized mean difference (g+ ) of 3.01, indicating that overall, hypochlorite treatments are highly effective. However, heterogeneity in g was significant (P less then 0.0001) among studies, wherein 69.8% of the variance observed in g was attributed to true effects. Further, an estimate of between-study variability was moderate (τ2 = 1.46)bacteria were significant, although they still accounted for up to 28% of the variance in true effect sizes associated with g+. These results show that although the current recommended rates for dose and contact time for commercial bleach products are generally expected to result in effective disinfestation, the efficacy against non-fungal plant pathogens is expected to be influenced by the organism type and target being treated with hypochlorite.Tobacco, Nicotiana tabacum L., is produced largely in China (~1/3 of the global market). In the monsoon summer of 2020, tobacco plant petioles, where axillary buds were removed, became black-rotten, and thick ooze appeared, when squeezed. Lesions encompassed more than half of petiole circumference. Ten tobacco fields (100 plant/field) were investigated in Liuyang, China and 5% disease severity founded in each infected field (Fig. 1A, B, C). Six infected stalks leave of different tobacco were sampled from severe field in Liuyang (N28°21', E113°52') and were surface sterilized (1% sodium hypochlorite for 3 min.), rinsed thrice in sterile distilled water, grounded, and streaked on Luria Bertani agar (LBA). After 24 hours at 28ºC, circular and convex colonies appeared. Hundred colony from ten plates were picked, amplified, and sequenced with the primer 16S-27F/16S-1492R by colony PCR (Lane et al. 1991). 16S rRNA sequence from 100 colony were assembled and fell into two sequences, either similar to Leclercia sp. (n diverse parts of China and identified as P. endophytica. To our knowledge, this is the first report of P. endophytica as a plant pathogen, which was firstly isolated from Tobacco planted in southern China.Atrial fibrillation and heart failure with reduced ejection fraction are increasing in prevalence worldwide. Atrial fibrillation can precipitate and can be a consequence of heart failure with reduced ejection fraction and cardiomyopathy. Atrial fibrillation and heart failure, when present together, are associated with worse outcomes. Together, these 2 conditions increase the risk of stroke, requiring oral anticoagulation in many or left atrial appendage closure in some. https://www.selleckchem.com/products/PHA-665752.html Medical management for rate and rhythm control of atrial fibrillation in heart failure remain hampered by variable success, intolerance, and adverse effects. In multiple randomized clinical trials in recent years, catheter ablation for atrial fibrillation in patients with heart failure and reduced ejection fraction has shown superiority in improving survival, quality of life, and ventricular function and reducing heart failure hospitalizations compared with antiarrhythmic drugs and rate control therapies. This has resulted in a paradigm shift in management toward nonpharmacological rhythm control of atrial fibrillation in heart failure with reduced ejection fraction.