Millertopp3951

To elucidate the epidemiology, anatomical, presentation, classification, pathology, investigative modalities, management and prognosis of primary angiosarcoma of the aorta.

A systematic review of literature from the database inception to January 2021 in PubMed and Embase, CINAHL and Cochrane Library in accordance to PRISMA was conducted. Retrieval and extraction was performed by two independent reviewers. The hierarchy of the evidence was assessed through the National Institute for Health and Care Excellence Checklist. Data were subjected to pooled prevalence analysis, Kaplan-Meier survival and test of probability using log-rank analysis. This review is registered with International Prospective Register of Systematic Reviews RD42021231314.

82 studies with

= 123 cases met the inclusion criterion. Abdominal (45%) aorta was the commonest anatomical site with female predominance in ascending aorta (41) and aortic arch (21). The longest survival was in the ascending aorta and the shortest in the abdominalatherosclerotic lesions are extremely suggestive of PA of the aorta at 5th and 6th decades of life.Medical assistance in dying (MAID) processes are complex, shaped by legislated directives, and influenced by the discourse regarding its emergence as an end-of-life care option. Physicians and nurse practitioners (NPs) are essential in determining the patient's eligibility and conducting MAID provisions. This research explored the exogenous factors influencing physicians' and NPs' non-participation in formal MAID processes. Using an interpretive description methodology, we interviewed 17 physicians and 18 NPs in Saskatchewan, Canada, who identified as non-participators in MAID. The non-participation factors were related to (a) the health care system they work within, (b) the communities where they live, (c) their current practice context, (d) how their participation choices were visible to others, (e) the risks of participation to themselves and others, (f) time factors, (g) the impact of participation on the patient's family, and (h) patient-HCP relationship, and contextual factors. Practice considerations to support the evolving social contact of care were identified.

An association between child sexual abuse (CSA) and attention deficit hyperactivity disorder (ADHD) has been documented. However, the temporal relationship between these problems and the roles of trauma-related symptoms or other forms of maltreatment remain unclear. This review aims to synthesize available research on CSA and ADHD, assess the methodological quality of the available research, and recommend future areas of inquiry.

Studies were searched in five databases including Medline and PsycINFO. Following a title and abstract screening, 151 full texts were reviewed and 28 were included. Inclusion criteria were sexual abuse occurred before 18 years old, published quantitative studies documenting at least a bivariate association between CSA and ADHD, and published in the past 5 years for dissertations/theses, in French or English. The methodological quality of studies was systematically assessed.

Most studies identified a significant association between CSA and ADHD; most studies conceptualized CSA as a precursor of ADHD, but only one study had a longitudinal design. The quality of the studies varied greatly with main limitations being the lack of (i) longitudinal designs, (ii) rigorous multimethod/ multiinformant assessments of CSA and ADHD, and (iii) control for two major confounders trauma-related symptoms and other forms of child maltreatment.

Given the lack of longitudinal studies, the directionality of the association remains unclear. The confounding role of other maltreatment forms and trauma-related symptoms also remains mostly unaddressed. Rigorous studies are needed to untangle the association between CSA and ADHD.

Given the lack of longitudinal studies, the directionality of the association remains unclear. The confounding role of other maltreatment forms and trauma-related symptoms also remains mostly unaddressed. Rigorous studies are needed to untangle the association between CSA and ADHD.Bovine parvovirus 1 (BPV1) is a causative agent of respiratory, gastrointestinal, and reproductive cattle diseases. We collected 149 yak diarrhea fecal samples from 9 farms in the Qinghai-Tibet Plateau. The samples were screened for BPV1 by PCR, and 2 samples were positive for BPV1. The complete genomes of these BPV1 isolates were sequenced successfully. selleck chemical The sequences of these 2 variants were both 5,515 bp in length and shared 96.5-96.8% identity with 2 previously reported BPV1 genomes (GenBank DQ335247, NC_001540). Twenty-six identical amino acid mutations were found in the 2 yak variants, including 7 amino acid substitutions in receptor-binding regions of the VP2 protein, and 5 amino acid substitutions in the NS1 protein C-terminal region that functions to activate transcription. The new genome sequences contribute to better understanding of the evolution and molecular characteristics of BPV1.Nurse scientists are increasingly interested in conducting secondary research using real world collections of biospecimens and health data. The purposes of this scoping review are to (a) identify federal regulations and norms that bear authority or give guidance over reuse of residual clinical biospecimens and health data, (b) summarize domain experts' interpretations of permissions of such reuse, and (c) summarize key issues for interpreting regulations and norms. Final analysis included 25 manuscripts and 23 regulations and norms. This review illustrates contextual complexity for reusing residual clinical biospecimens and health data, and explores issues such as privacy, confidentiality, and deriving genetic information from biospecimens. Inconsistencies make it difficult to interpret, which regulations or norms apply, or if applicable regulations or norms are congruent. Tools are necessary to support consistent, expert-informed consent processes and downstream reuse of residual clinical biospecimens and health data by nurse scientists.Although sibling sexual abuse (SSA) is one of the most common forms of sexual abuse, it has been particularly neglected in previous research. Hence, characteristics of this form of abuse and its longer term implications are not well understood. The aims of the current review were to precisely characterize the phenomenon of SSA and to condense the implications known to date of SSA on survivors. We included 15 studies with a total sample size of 14,680 individuals. Our results indicate that SSA has some unequivocal features such as an early onset, an extended duration and frequency, and a particularly high intensity (i.e., involvement of coercion, force, superiority, and manipulation). Our findings also revealed that SSA is linked to later depression, anxiety, impaired self-esteem, and sexual functioning. The findings of the current review suggest that (1) SSA is common, (2) SSA has various negative effects on survivors' mental health, and that (3) SSA and its implications have been and to date are marginalized in research and practice. Results are discussed with a special focus on clinical implications.Technology is widely used to support qualitative research. Computer-Assisted Qualitative Data Analysis Software (CAQDAS) encompasses complementary technologies to support qualitative analysis. Advantages of CAQDAS include efficient management of data and transparency in analysis. Disadvantages include heavy emphasis on coding as a distractor from analysis and considerable time to learn the program. In this methods article, we, as less experienced, qualitative researchers describe our experiences using NVivo, a CAQDAS program, in a descriptive phenomenological study using Colaizzi's method. Over 1 year, 24 postpartum women were given a secure research link to record their experiences with pain and depression during the third trimester of pregnancy. Although NVivo analysis was helpful, the philosophy of phenomenology, reflexivity, and Colaizzi's method directed researchers away from NVivo for the final summation. Recommendations for future use of CAQDAS used concurrently with Colaizzi's method include the use of word clouds and other visualizations for bracketing and triangulation.Investigations into Fourier beamforming for medical ultrasound imaging have largely been limited to plane-wave and single-element transmissions. The main aim of this work is to generalize Fourier beamforming to enable synthetic aperture imaging with arbitrary transmit sequences. When applied to focused transmit beams, the proposed approach yields a full-waveform-based alternative to virtual-source synthetic aperture, which has implications for both coherence imaging and sound speed estimation. When compared to virtual-source synthetic aperture and retrospective encoding for conventional ultrasound sequences (REFoCUS), the proposed imaging technique shows an 8.6 and 3.8 dB improvement in contrast over virtual source synthetic aperture and REFoCUS, respectively, and a 55% improvement in point target resolution over virtual source synthetic aperture. The proposed image reconstruction technique also demonstrates general imaging improvements in vivo, while avoiding limitations seen in prior techniques.To determine the relationship between muscle echo intensity (EI) and fractal dimension (FD), and the diagnostic performance of both ultrasound parameters for the identification of frailty phenotype. A retrospective interpretation of ultrasound scans from a previous cohort (November 2014-February 2015) was performed. The sample included healthy participants less then 60 years old, and participants ≥60 divided into robust, pre-frail, and frail groups according to Fried frailty criteria. A region of interest of the rectus femoris from the ultrasound scan was segmented, and histogram function was applied to obtain EI. For fractal analysis, images were processed using two-dimensional box-counting techniques to calculate FD. Statistical analyses were performed with diagnostic performance tests. A total of 102 participants (mean age 63 ± 16, 57 men) were evaluated. Muscle fractal dimension correlated with EI (r = .38, p  less then  .01) and showed different pattern in the scatter plots when participants were grouped by non-frail (control + robust) and frail (pre-frail + frail). The diagnostic accuracy for EI to categorize frailty was of 0.69 (95%CI 0.59-0.78, p = .001), with high intra-rater (ICC 0.98, 95%CI 0.98-0.99); p  less then  .001) and inter-rater (ICC 0.89, 95%CI 0.75-0.95; p  less then  .001) reliability and low measurement error for both parameters (EI -0.18, LOA95% -10.8 to 10.5; FD 0.00, LOA95% -0.09 to 0.10) in arbitrary units. The ROC curve combining both parameters was not better than EI alone (p = .18). Muscle FD correlated with EI and showed different patterns according to frailty phenotype, with EI outperforming FD as a possible diagnostic tool for frailty.Adolescents experience alarmingly high rates of sexual violence, higher than any other age-group. This is concerning as sexual violence can have detrimental effects on teens' personal and relational well-being, causing long-term consequences for the survivor. Still, adolescents are hesitant to report the assault or seek out services and resources. When an adolescent survivor does seek out services, they may interact with a provider who is a mandatory reporter. This scoping review sought to synthesize the current U.S.-based research on the role, challenges, and impact of mandatory reporting (MR) in the context of adolescent sexual assault. Database searches using key words related to MR, sexual assault, and adolescence identified 29 peer-reviewed articles. However, none of these articles reported on empirical investigations of the phenomenon of interest and instead consisted of case studies, commentaries, and position papers. The scoping review was expanded to provide a lay of the land of what we know about the intersection of adolescent sexual assault and MR.