Meyersmcclure9899

This cohort had mean (±SEM) preoperative syrinx area of 23.9 ± 10.0 mm2. Postoperatively, the mean syrinx area increased to 40.5 ± 9.6 mm2 and 57.3 ± 12.5 mm2 on the first and latest postoperative scans available (P = 0.02), for an increase of 106.9% ± 94.4% and 186.0% ± 107.4% (P = 0.04). Presenting symptoms included occipital headache, paresthesias, visual deterioration, and paraspinal pain. On last follow-up (mean 13.9 ± 4.9 months), the majority of symptoms were resolved in this cohort, despite persistence of syringomyelia. CONCLUSIONS In this small cohort of unique patients, syrinx resolution was not achieved via decompression surgery. Despite "radiographic failure," good symptom control was achieved, with most patients remaining or becoming asymptomatic postoperatively, thus supporting our rationale for what has largely been a conservative approach in this population. BACKGROUND Cervicomedullary compression in young children has been described in the context of Chiari type 1 malformation, with symptoms associated with the extent of tonsillar herniation below McRae line. Historically, Chiari type 1 malformation has been defined by tonsillar herniation of at least 5 mm. However, in certain populations, including very young children, Chiari symptoms may be present without this finding. A new Chiari classification is thus necessary. METHODS Cases involving patients up to 5 years of age evaluated for possible posterior fossa decompression were retrospectively reviewed. Preoperative symptoms, magnetic resonance imaging findings, surgical management, and short- and long-term outcome and follow-up were recorded. Tonsillar descent and presence of ventral herniation (VH) were recorded. We define VH as the tonsils crossing a line that bisects the caudal medulla at the level of the foramen magnum, thus creating a novel entity, Chiari type 0.5 malformation. Patients with ventrally herniated tonsils were compared with patients exhibiting more typical Chiari morphology. RESULTS Of 41 cases retrospectively reviewed, 20 met criteria for VH. These differed from cases without VH because of the predominance of medullary symptoms. In the VH cohort, 11 patients underwent surgical decompression with symptom resolution; 9 were initially managed conservatively, but 3 subsequently required surgery. CONCLUSIONS We define a novel Chiari entity, Chiari type 0.5 malformation, characterized by ventral tonsillar wrapping around the medulla in young children in the absence of classic Chiari type 1 malformation imaging findings. These patients are more likely to present with medullary symptoms than patients without VH. They are also more likely to require surgical decompression and respond favorably to intervention. OBJECTIVE This study aimed to examine whether honey and propolis Trigona can reduce the level of leptin in central obesity human. METHODS It was a quasi-experimental study, population and sample were central obesity and normal weight as control. Sample size was 30 participants taken using purposive sampling. RESULTS Intervention as long as 14 days make an increased level of leptin as many as 97.076pg/ml in control group and decreasing respectively 171.803pg/ml and 245.293pg/ml in honey and propolis intervention group, both significant statistically. The dose of honey given was 105mg/days divided into 3 packs, and each pack contains 35mg. The dose of propolis was 60mg/days and divided into 3 capsules, each of it contains 20mg. Intervention as long as 14 days and leptin levels examined using human ELISA Kit three times, that is before intervention, 7 days after the intervention and 14 days after intervention. CONCLUSION Honey and propolis Trigona has the ability to decrease leptin level of central obesity participants. E7766 clinical trial These honey bee products are potential to be a dietary supplement for central obesity patients. OBJECTIVE To evaluate the prevalence of anemia in pregnancy and determine the relationship between maternal anemia during pregnancy and low birth weight, babies. METHODS This study was a cross-sectional design which was conducted at Siti Khadijah 1 Tertiary Hospital from January 2017 to October 2018. The total sample of the study was 6876 samples. RESULTS Anemia prevalence was 46.6%. Mothers with anemia were more likely to give birth to babies with low birth weight compared to mothers who were not anemic, which is 373 respondents (11.7%) versus 265 respondents (7.2%). Respondents with severe anemia gave birth to more babies with low birth weight than babies with normal birth weight, which is 49 people (92.5%) versus 4 (7.5%) (p=0.000, p less then 0.05). CONCLUSION There was a significant association between maternal hemoglobin and birth weight. L.U.OBJECTIVE The objective of this study was analyzed HNP1 and HNP3 level of deteriorating sepsis patients. METHODS It was a cross-sectional study that observed HNP and sepsis level, samples size were 40 patients taken by consecutive random sampling. Analysis of HNP serum level use enzyme-linked immunosorbent assay (ELISA), data analyzed used independent T-test and presented in tables with mean, standard deviation, mean difference and probability value. RESULTS Results show that when patients become deteriorate or shock sepsis, HNP1 levels increase dramatically, which is 356.2pg/ml higher than sepsis patients and statistically significant (p=0.016, p≤0.05). It is similar to HNP3 level, which is 2.04ng/ml higher than with sepsis patients and statistically significant (p=0.021, p≤0.05). CONCLUSION This study reveals that HNP1 and HNP3 level increases dramatically in deteriorate sepsis patients. Level of HNP1 and HNP3 of sepsis patient is higher than nonsepsis patient, shock sepsis patient is higher than sepsis patient and both HNP1 and HNP3 level is higher in die patient compare to alive patient. OBJECTIVE This study aimed to determine the description of the incidence of insulin resistance (IR) in pregnant women in maternal and child hospital Khadijah Makassar. METHODS This research was a cross-sectional study, a research site at the Polyclinic of Khadijah Mother and Child Hospital, which was conducted from February 2019 to April 2019. The sample of the study were 87 pregnant women, insulin resistance calculated based on the HOMA-IR index=fasting blood glucose (mg/dl)×Fasting insulin (μ/ml)/405. HOMA-IR index was divided into 3 tertiles, namely tertile 1 (3.10-5.84), tertile 2 (5.85-8.62), and tertile 3 (8.63-35.26), categorized as insulin resistance if HOMA-IR was in tertile 3. RESULTS Respondents in this study were mostly aged less then 35 years, i.e., 71 (81.6%) with the majority of gestational age already in the 3rd semester and nutritional status as measured by the upper arm circumference was also the normal, and ethnic was Makassar The number who experienced insulin resistance, i.e., 29 people (33.