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In addition, fear of COVID-19, COVID-19 risk, and mental health problems (i.e., depression, anxiety, and suicidality) showed a significant relationship in terms of insomnia. A total of 31.2% variance predicting insomnia was identified considering all of the studied variables.

The prevalence of insomnia reported herein seems relatively lower than the prior studies, but this figure is not neglectable. Thus, the identified associated factors are highly suggested to consider in policy actions with a special focus on mental health problems to elevate the risk of sleep problems.

The prevalence of insomnia reported herein seems relatively lower than the prior studies, but this figure is not neglectable. Thus, the identified associated factors are highly suggested to consider in policy actions with a special focus on mental health problems to elevate the risk of sleep problems.Acknowledgement of scientific achievements was and is essentially achieved through the citation of a publication. Increasingly, however, it is no longer just the publication itself that plays an important role, but also the degree of attention that a scientist achieves with this very publication. Thus, the importance of strategic behavior in science is progressing and an awareness mentality is spreading. In this paper, the causes and backgrounds of this development are discussed, identifying the use of reductionist, quantitative systems in science management and research funding, the loss of critical judgment and technocratic dominance, quantitative assessments used for decision making, altmetrics and the like as alternative views, the use of perception scores in reference databases and universities as well as ambitions of journals as main drivers. Besides, different forms of strategic behavior in science and the resulting consequences and impacts are being highlighted.Fruit and vegetable consumption is recommended in numerous food-based dietary guidelines and forms a key recommendation in many international statements related to healthy diets. There are thousands of fruit and vegetable species from which to choose, but despite this abundance from nature, populations in most countries neither produce nor consume the recommended daily amounts of fruits and vegetables. There is enormous potential to better incorporate the wealth of diverse fruit and vegetable species and varieties into food systems. Known and preserved by indigenous communities, these hidden food treasures can foster collaborative research and learning. This perspective from the Task Force on Traditional and Indigenous Food Systems and Nutrition of the International Union of Nutritional Sciences (IUNS) highlights 5 key actions that can be taken by individuals, communities, and nations to reshape dialogue about traditional and indigenous fruits and vegetables to benefit people and planetary ecosystems.Homologous recombination DNA repair deficiency (HRD) is associated with sensitivity to platinum and poly (ADP-ribose) polymerase inhibitors in certain cancer types, including breast, ovarian, pancreatic, and prostate. In these cancers, BRCA1/2 alterations and genomic scar signatures are useful indicators for assessing HRD. However, alterations in other homologous recombination repair (HRR)-related genes and their clinical significance in other cancer types have not been adequately and systematically investigated.

We obtained data sets of all solid tumors in The Cancer Genome Atlas and Cancer Cell Line Encyclopedia, and comprehensively analyzed HRR pathway gene alterations, their loss-of-heterozygosity status, and per-sample genomic scar scores, that is, the HRD score and mutational signature 3 ratio, DNA methylation profiles, gene expression profiles, somatic

mutations, sex, and clinical or in vitro response to chemical exposure.

Biallelic alterations in HRR genes other than

were also associated withgnificance of homologous recombination deficiency.[This corrects the article DOI 10.1021/acsomega.0c00358.].Diesel particulate matter (DPM) and oxides of nitrogen (NOx) are the emissions from diesel engines (compression ignition engines) of the most concern and are currently strictly regulated. In this work, we present an alternative diesel emission control technique to assist in further emission reduction. An experiment-oriented study on diesel engine emission abatement using low-power, low-frequency, high-voltage discharge (HVD) treatment was carried out in a laboratory-scale reactor with whole diesel engine exhaust gas. A dielectric barrier discharge (DBD) reactor was used in direct contact with diesel exhaust gas at atmospheric temperature with an input energy density between 200 and 400 J/L. An investigation of the direct effect of the high-voltage discharge reactor on the diesel exhaust gas treatment was carried out to characterize both diesel particle and gaseous emissions. The proposed HVD system demonstrated up to 95% particulate matter reduction by mass or 64% reduction by number, and 63% reduction of the diesel soot particle geometrical mean diameter by HVD-generated O3 oxidation. Thermogravimetric analysis revealed the significant change in the diesel soot compositions and oxidation characteristics. HVD-treated particulate matter demonstrated a lower reactivity in comparison to untreated soot. Gas composition analysis indicated the generation of free radicals (e, O, OH, O3, and N) by the HVD system, as mainly indicated by the increase of the NO2/NO ratio and concentration of CO and O2. The pattern of CO2 reduction while CO and O2 increased indicated the dissociation of CO2 by HVD. this website Free radicals generated by HVD directly affected DeNO, DeNOx, NO2/NO ratio, and CO and CO2 selectivities.New classes of unexplored benzo[b]thiolanes are synthesized from trisubstituted thioamides through copper-catalyzed intramolecular S-arylation of thioamides for the first time. This method provides good to excellent yields with fully controlled chemoselectivity. Unusually, iminobenzo[b]thiolanes are very stable under mild acidic conditions. A plausible mechanism is proposed for the chemoselective S-arylation process.The impacts of FeS catalysts on the hydromodification and structural evolution of lignite were investigated using Fourier transform infrared spectroscopy, nuclear magnetic resonance, and X-ray photoelectron spectroscopy. The results indicate that the caking property of lignite can be significantly improved in the presence of the FeS catalyst. When 6.0 wt % FeS was added, the maximum caking index (G RI) of modified coal reached 95. During the hydromodification, FeS has little effect on the intrinsic water gas shift reaction, but it can increase the CO conversion by promoting the decomposition and hydrogenation of coal so that more active hydrogen is generated and introduced into modified coal. FeS is conducive to the rupture of distal aliphatic groups in the extractible solutes, which promotes the entrance of hydrogen into the aromatic nucleus (Har) and α positions (Hα) of asphaltenes and β positions (Hβ) of preasphaltenes. After the catalytic hydromodification, the longer side chains or bridge bonds break and are hydrogenated to form the aliphatic structures with a shorter chain or a higher branched degree. Meanwhile, more oxygen-containing functional groups were removed along with the reduction of volatiles in the modified coal. The synergistic effect of FeS on these factors is favorable for the generation of plastic materials, which contributes to the development of the caking property of lignite.Nanoparticles are attracting attention as drug carriers for realizing "theranostics". However, nanoparticles generally show long blood circulation behaviors, and the remaining nanoparticle probe in the blood is the cause of prolonged optimal time from probe injection to imaging. Recently, it has been reported that some nanoparticles activate the immune system, producing an anti-nanoparticle antibody, which can selectively detect the corresponding nanoparticle and transfer it to the liver by opsonization. Lactosome is a polymer micelle prepared from amphiphilic PNMG-block-PLLA polydepsipeptide and known to activate the immune system when administered to mice at a specific concentration. In this study, radioactive fluorine-labeled lactosome (18F-lactosome) is used as a positron emission tomography probe for tumor imaging, and anti-lactosome antibody was additionally administrated after 2 h from the probe dosage. 18F-lactosome remaining in the blood was opsonized by the anti-lactosome antibody and transferred to the liver under the antibody dose-dependent manner. Because of the probe reduction from the blood, the tumor/blood signal intensity ratio could be improved up to 50% by anti-lactosome antibody administration. There needs further improvement, but the developed method is applicable for imaging utilizing nanoparticle probes, which activate the immune system.Titanium(III) is a useful strong reductant and is usually standardized with iron(III) in volumetric analysis. Iron(III) is widely used as an oxidant and is usually standardized with thiosulfate ions through an iodine liberation reaction. The evaluation of the standardization procedure for iron(III) with thiosulfate ions is therefore essential to ensure the reliability of standardized titanium(III) solutions. To investigate the titration procedure for iron(III), two different titrations were performed redox titration with thiosulfate ions through an iodine liberation reaction and chelatometric titration with disodium dihydrogen ethylenediaminetetraacetate. Subsequently, for the investigation of standardization of iron(III), titanium(III) was assayed through two titration paths redox titration with standardized iron(III) and redox titration with standard potassium dichromate. The reliability of titrimetric procedures was evaluated by applying several different stoichiometric reactions to each chemical. All titrimetric procedures were consistent with each other within their expanded uncertainties and were capable of providing reliable volumetric standards with careful operations presented in this study.The bis(trifluoromethanesulfonyl)amide anion (Tf2N), which is a common component of ionic liquids, often exhibits disorder in the solid state. In this study, the phase transitions and crystal structures of the Tf2N salts of 1,1‴-dineopentyl-1',1″-biferrocene (=npBifc), 1',1″-biferrocene (=Bifc), ferrocene, and cobaltocene (1-4, respectively) were compared. All the salts exhibited phase transitions at low temperatures, which are accompanied by anion ordering, though the ordering was not complete in 2 and 3. X-ray crystallographic investigation revealed that the cations and anions in 1 and 2 adopted alternating arrangements and segregated columnar arrangements, respectively. The cation in 1 exhibited a symmetrical, average-valence structure in the room-temperature phase owing to rapid valence tautomerization, whereas the cation exhibited an unsymmetrical structure in the low-temperature phase. The cation in 2 exhibited an unsymmetrical, trapped-valence structure in both phases. The cation valence states in these salts were accounted for by the electrostatic interactions between the cations and anions. The crystal structures and phase behavior of the ferrocenium salt 3 were very different from those of 4.