Mcmanuswu6261

Wastewaters containing tetracycline (TC) are produced in many industries, and biotechnology is an economic way to treat it. In this work, aerobic granular sludge (AGS) modified with in-situ generated biogenic manganese oxides (BioMnOx), named after manganese-oxidizing AGS (Mn-AGS), was used to treat TC in wastewater. Comparisons between Mn-AGS and AGS indicated that Mn-AGS showed superior TC resistance and treatment results than AGS. The activity of Mn-AGS was not inhibited by TC content as high as 20 mg/L. Wastewater TC could be removed stably and efficiently (95.2 ± 0.8%) in the Mn-AGS reactors after 119 days' acclimation. Furthermore, TC may be first adsorbed on Mn-AGS sludge and then degraded by both microbial community and BioMnOx. TC adsorption could be greatly improved by increasing solution pH, which can be attributed to the increase in negatively charged TC species at high pHs. The microbial community changed greatly after TC exposure and some TC-resistant bacteria, such as Flavobacterium, were enriched in the final sludge. Moreover, the antibiotic resistance genes (ARGs) tetA, tetG, and tetX largely increased and the microorganisms were TC-resistant through efflux pumps and antibiotic inactivation mechanisms. This work suggests a new biological-chemical coupling strategy, Mn-AGS, to treat antibiotics in organic wastewater with high efficiency and stability.Heavy metals (HMs) such as vanadium (V), zinc (Zn), arsenic (As), chromium (Cr), copper (Cu) and nickel (Ni) are released into atmosphere during V smelting activities, resulting in their co-existence with airborne microbes. However, little is known about HMs distributions and associated microbes in aerosols from such industrial districts. This study reveals seasonal dynamics of HMs and microbes in ambient aerosols from V smelter in Panzhihua, China. Multiple HMs were detected, while V concentration was the highest, maximizing at 228.0 ± 10.3 ng/m3 in Spring. Health risks displayed similar trends to HMs distributions, and children were posed much higher risks than adults due to their more sensitivity to HMs. V and As contributed dramatically to total health risks among all examined HMs. High-throughput 16S rRNA gene sequencing analysis revealed microbes tolerant to V, Zn, As, Cr, Cu and Ni. Acinetobacter widely existed with function of detoxifying V(V) and more species as Bacillus, Gobacter and Thauera tolerating V, Zn, As, Cr, Cu and Ni appeared in Summer. These findings shed light on understandings of HMs dynamics and associated microbial community in aerosols from smelting regions.A fast mobility particle sizer operating at a one-second time resolution was used to measure aerosol particle number size distribution (5.6-560 nm) in marine conditions over the South China Sea (SCS) from 29 March to 2 May 2017 and in the tropic zone of the Northwest Pacific Ocean (NWPO) from 10 to 29 October 2018. The clean background number concentration of nucleation mode atmospheric particles ( less then 30 nm) was approximately 0.6 × 103 cm-3 in these areas. Two nighttime and five daytime strong new particle formation (NPF) events were observed to occur extending over a spatial scale from 2 to 140 km in the SCS, with a net increase of nucleation mode particles of 4.5 × 104 cm-3 ± 3.4 × 104 cm-3 during five of the seven events. Nighttime NPF events were unlikely associated with sulfuric acid vapor because of lack of photochemical reactions. Daytime NPF events share several common features with nighttime NPF events, e.g., dramatic spatiotemporal variations in the number concentration of the nucleation mode particles. Without aerosol precursor measurements we cannot address the vapors driving the formation process. However, our results show no banana-shaped growth of the particles. The growth into larger particle sizes seems to be restricted by the availability of condensable components in the gas phase. The nucleation mode was observed and sometimes even dominated the number concentration over other particle modes in the marine atmosphere over the tropic zone of the NWPO. In addition, more data obtained during the two campaigns and other campaigns were also applied to strengthen the analysis in terms of origins, formation and absent growth of nucleation mode particles in the marine atmospheres over the two tropic zones.The excess or deficiency of trace metals can cause adverse neurocognitive development. Evidence of health effect of trace metal mixtures on neurocognitive development is limited in children. We evaluated associations of prenatal exposure to trace metals and metal mixtures with neurocognitive development of 2-year-old children. A total of 544 mother-child pairs were included in the study. The concentrations of 10 trace metals in maternal urine were monitored before delivery. Neurocognitive development indexes, including mental development index (MDI) and psychomotor development index (PDI), were assessed using the Bayley Scales of Infant Development. Linear regression analysis was performed to explore the effects of single-metal and multi-metal exposures. selleck screening library Bayesian Kernel Machine regression (BKMR) was used to investigate overall effect of exposure to metal mixtures and potential interactions among mixture components. We found positive associations of urinary strontium (Sr) and Selenium (Se) levels with MDI scores among all children in the single-metal model. Sr was positively related to MDI, while Manganese (Mn) was negatively associated with PDI in the multi-metal model. The results from BKMR model in girls revealed that MDI scores were improved with the increasing concentrations of Sr, Se and Mn mixture until the concentrations reached their 30th percentiles (Sr 149.49 μg/g creatinine, Se18.38 μg/g creatinine, Mn1.96 μg/g creatinine), with no effect after that threshold level. Sr played a positive role in mental development among mixture components, which was consistent with the results of Sr in the multi-metal models. No signification association of mixture with MDI/PDI was found in boys. The study suggested potential sex-specific association of Sr, Se and Mn mixture levels (at or below their 30th percentiles) with improved mental development, and beneficial role of Sr.