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Concurrently, in-street barriers are widely applicable to rectify the poor roadside air quality in existing street canyons. They are broadly classified into porous (e.g. trees and hedges) and solid (e.g. kerbside parked cars, noise fences and viaducts) barriers that utilize their aerodynamic advantages to ease roadside air pollution. Post-evaluations are needed to review these strategies by real-world field experiments and more detailed modelling in the practical perspective.Recently, the use of accelerated carbonation curing has attracted wide attention as a promising method to reduce carbon dioxide (CO2) emission and improve the mechanical properties of cement-based materials. However, the diffusion mechanism of CO2 in the matrix and the content of hydration products are the key factors that restrict the carbonation reaction rate. To understand the combined behavior of hydration and carbonation reactions, this paper investigates the influence of cement hydration induced by water-to-cement ratio (w/c) (ranging from 0.25 to 0.45) on microstructure and microhardness properties of cement paste. The experimental results demonstrated that carbonation only occurred at the surface layer of cement paste samples and carbonation efficiency was significantly influenced by greater hydration due to higher w/c. The carbonation depth of the sample with 0.45 w/c was about 6 times higher than that of sample with 0.25 w/c after 28 days of CO2 curing. XRD results revealed that calcite-type calcium carbonate is the main carbonation product and consumption of clinker phases (C2S and C3S) during the hydration enhanced the calcite precipitation in the pores of the surface layer. According to FTIR, with increasing w/c, the position of Si-O-Si stretching bond of the carbonated surface changed from Q2 to Q3, confirming the formation of amorphous silica-rich gel, along with the appearance of CO32- bonds related to calcite. In overall, the micro-mechanical analysis in this study showed that the carbonation significantly improved the surface microhardness of cement paste samples, while the refinement of capillary pores due to carbonation also decreased the negative impact of large pores formed in the matrix of cement paste prepared with high w/c.Biomass of Java plum (JP) and amaltash (AT) seeds were employed to remove arsenic from synthetic wastewater, cost effectively. The prepared biomasses were characterized by FE-SEM, EDX, FTIR, XRD, and ICP techniques. Experimentation the optimization study has been carried out by using Design-software 6.0.8. Response surface methodology has been applied to design the experiments where we have used three factors and three levels Box-Behnken design (BBD). Arsenic removal ability of bio-sorbents was evaluated and optimized by varying pH, adsorbent dose concentration of arsenic in synthetic wastewater. For 2.5 mg/L arsenic concentration and 80 mg adsorbent dose at pH 8.8 Java plum seeds (JP) based bio-adsorbent removed ∼93% and amaltash seeds (AT) based bio-adsorbent removed ∼91% arsenic from synthetic wastewater. The adsorption behaviour better explained following Freundlich model (R2 = 0.99) compared to Temkin model (R2 = 0.986) for As (III) ions. The adsorption capacity was 1.45 mg g-1 and 1.42 mg g-1 for JP and AT, respectively after 80 min under optimal set of condition. The adsorption kinetics was explained by either pseudo-first order model or Elovich model.

The COVID-19 pandemic and resulting public health measures may have major impacts on mental health, including on self-harm. We have investigated what factors related to the pandemic influenced hospital presentations following self-harm during lockdown in England.

Mental health clinicians assessing individuals aged 18 years and over presenting to hospitals in Oxford and Derby following self-harm during the period March 23rd to May 17, 2020 recorded whether the self-harm was related to the impact of COVID-19 and, if so, what specific factors were relevant. These factors were organized into a classification scheme. Information was also collected on patients' demographic characteristics, method of self-harm and suicide intent.

Of 228 patients assessed, in 46.9% (N=107) COVID-19 and lockdown restrictions were identified as influencing self-harm. This applied more to females than males (53.5%, N=68/127 v 38.6%, N=39/101, χ

=5.03, p=0.025), but there were no differences in age, methods of self-harm or suicideVID-related factors can be used as an aide-memoire for clinicians.

COVID-related factors were identified as influences in nearly half of individuals presenting to hospitals following self-harm in the period following introduction of lockdown restrictions. Females were particularly affected. The fact that mental health problems, including issues with delivery of care, predominated has implications for organisation of services during such periods. The contribution of isolation, loneliness and sense of entrapment highlight the need for relatives, friends and neighbours to be encouraged to reach out to others, especially those living alone. PCNA-I1 DNA activator The classification of COVID-related factors can be used as an aide-memoire for clinicians.Suicide accounts for approximately 800,000 deaths per year globally. Previous research has shown that intranasal esketamine and intravenous ketamine can rapidly decrease the severity of depressive symptoms and suicidal ideation. However, the majority of clinical trials excluded individuals with moderate to high baseline suicidality scores (e.g., suicidal ideation with plan/intent at the time of recruitment). The current review aims to evaluate the effect of esketamine and ketamine in patients with suicidal ideation at baseline. A systematic search was conducted on EMBASE, PsychInfo and PubMed from inception to July 2020 following the PRISMA guidelines. 15 studies met inclusion criteria. Results from esketamine trials did not demonstrate antisuicidal effects, as between-group differences were not found. Intravenous ketamine appeared to rapidly decrease the severity of suicidal ideation and depressive symptoms in individuals with baseline suicidal ideation, though retrospective studies suggest that these effects may be short-lasting. During the double-blind treatment phases, 2.4% of patients from the treatment groups and 1.5% of patients from control groups attempted suicide, with zero deaths by suicide in both the treatment and control groups during this phase. Based on the overall pooled samples, studies were assessed to be relatively safe, and the continual inclusion of this study population in future clinical trials is encouraged. Future research should aim to assess the longitudinal efficacy of ketamine in patients with baseline suicidality.There is a gap in the literature investigating the impact of obstetric complications on subsequent mental ill health outcomes. The aim of this study was to establish the association between post-partum haemorrhage (PPH) and mental ill health. We conducted a retrospective open cohort study utilizing linked primary care (The Health Improvement Network (THIN)) and English secondary care (Hospital Episode Statistics (HES)) databases, from January 1, 1990 to January 31, 2018. A total of 42,327 women were included 14,109 of them were exposed to PPH during the study period and 28,218 unexposed controls were matched for age and date of delivery. Hazard ratios (HRs) for mental illness among women with and without exposure to PPH were estimated after controlling for covariates. Women who had had PPH were at an increased risk of developing postnatal depression (adjusted HR 1·10, 95%CI 1·01-1·21) and post-traumatic stress disorder (PTSD) (adjusted HR 1·17, 95%CI 0·73-1·89) compared to women unexposed to PPH. When restricting the follow-up to the first year after childbirth, the adjusted HR for PTSD was 3·44 (95% CI 1·31-9·03). No increase in the overall risk was observed for other mental illnesses, including depression (adjusted HR 0·94, 95%CI 0·87-1·01), severe mental illness (adjusted HR 0·65, 95%CI 0·40-1·08, p = 0·239) and anxiety (adjusted HR 0·99, 95%CI 0·90-1·09). PPH is associated with a significant increase in the risk of developing postnatal depression and PTSD in the first year after delivery. Active monitoring for mental illness should form an integral part of the follow-up in women who suffered a PPH.

Subjective Memory Complaints (SMC) along with cognitive deficits are frequently observed in patients with Major Depressive Disorder (MDD). The relationship between SMC and objective memory performance in patients with MDD was evaluated, in comparison with patients with Mild Cognitive Impairment due to Alzheimer's Disease (MCI-AD) and healthy controls (HC).

Patients with MDD (n=47), MCI-AD (n=43) and HC (n=45) were assessed with a self-report memory complaints scale (SMCS) and underwent a comprehensive clinical and neuropsychological assessment. A discrepancy score between the Logical Memory delayed recall and the SMCS total score was calculated as a measure of memory awareness.

Patients with MDD (12.5±4.4) and patients with MCI-AD (10.9±4.1) had not significantly different SMCS total scores, whereas HC showed significantly lower scores (4.0±3.0). As much as 74.5% of patients with MDD patients and 65.1% of patients with MCI-AD reported prominent memory complaints, whereas only 4.4% of HC did. Patients with MDD had relatively preserved memory tests, resulting in a higher discrepancy score than both patients with MCI-AD and HC. The SMCS total score correlated positively with depressive symptoms in the 3 groups of participants.

Patients with MDD showed inaccurate memory self-awareness as they under-estimated their memory functioning, a pattern distinct from both patients with MCI-AD and HC.

Patients with MDD showed inaccurate memory self-awareness as they under-estimated their memory functioning, a pattern distinct from both patients with MCI-AD and HC.While mammary gland tissues (MGTs) are difficult to sample without risks for cow's health or milk production, milk analysis are used in routine to assess dairy cow udder's health. This study aimed to identify, quantify, compare the milk and MGTs microbiota of macroscopically healthy dairy bovine mammary glands (MG) in order to evaluate their degree of similarity. We harvested 13 couples of milk and MGTs samples, originated from the same quarter at culling. 16S rDNA Amplicon Sequencing was performed, showing Corynebacterium as the main bacterial genus in both types of samples but generally found in the milk in higher proportions than in tissues. Species evenness was higher in MGTs while species richness was higher in milk samples. Beta diversity was significantly different between both matrices suggesting the presence of a resident microbiota in MGTs of dairy cows at time of culling partially reflected by the milk microbiota from the same quarter.Suicide is a crucial public health problem with a serious harmful impact on individuals, families, and societies. Therefore, the current study aimed to evaluate the predictors of death or serious injury related outcome regarding this lethal phenomenon in Hamadan Province. In this registry-based study we used all of suicide attempt entered in Hamadan Suicide Registry Program from January 2016 to the end of 2017. Serious injury and death were considered as suicide worse outcome and its prognostic factors were examined using logistic regression model. From 2493 patients with suicide attempts in 5.61 % and 4.09 % of them, suicide behaviour led to serious injury and death, respectively. Males had 2.83 times higher odds of the worse suicide outcomes ([OR = 2.83, 95 % CI 1.71, 4.68)], P  less then  0.001). Moreover, the odds of worse outcomes of suicide in individuals with low level of education, advanced age and with the history of suicidal ideation was significantly higher (P  less then  0.05). Among different suicide methods, the highest odds of suicide worse outcomes were related to self-immolation, falls, hanging, self-harm, poisoning, and drugs (P  less then  0.