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ems, and making HIV screening services available in all healthcare facilities are crucial to decrease HIV infection. Special attention is also required to avoid risk factors that increased HIV incidence among females.

After the initiation of highly active antiretroviral therapy (HAART), successful HAART is characterized by an increase in the CD4

count. Several factors affect the CD4

T-cell count. This study aimed to assess the immunological response during HAART and determinants of the current CD4

T-cell count among HIV/AIDS patients on HAART.

A hospital-based cross-sectional study was conducted from February 1 to April 1, 2017. A total of 423 HIV/AIDS patients on HAART were enrolled using simple random sampling. Descriptive statistics, and bivariate and multiple regression analyses were conducted. Variables with

-value <0.2 in the bivariate analysis were entered in the multiple regression models.

-Values <0.05 and 95% confidence intervals were used to identify determinants of the current CD4

T-cell count.

The mean CD4

T-cell count gradually increased until 8 years on HAART but declined thereafter. An increased current CD4

T-cell count was observed among patients with an initial regimen of pediaSex, type of initial regimen, baseline adherence, baseline CD4+ count, viral load, and duration on HAART were independent determinants of current CD4+ count. These determinants could be addressed by regular monitoring of HIV patients on HAART, and special attention should be paid to male patients.Pre-exposure prophylaxis (PrEP) against HIV infection with tenofovir/emtricitabine is proven to be effective yet uptake of this preventive measure has been difficult due to several barriers such as cost, access, and misinformation. Certain subpopulations are disproportionately affected by this problem. Several methods have been developed to close the gap in care. New antiretroviral treatment strategies are being investigated for safety and efficacy in preventing HIV infection.

Although Tanzania experiences a general decline in HIV prevalence, some populations such as caregivers of orphans may be at a higher risk than the general population, suggesting that infection pathways still need further exploration. This study examines how food insufficiency relates to HIV infection among caregivers of orphans and vulnerable children (OVC) in Tanzania.

Data are from a community-based, USAID-funded Kizazi Kipya project that aims at increasing the uptake of HIV services, as well as other health and social services by OVC and their caregivers in Tanzania. Caregivers who were enrolled in the project from January to July 2017 in seven regions of Tanzania, and had reported their HIV status to the project, were included in the analysis. While HIV status was the outcome, the main independent variable was food insufficiency which was assessed using the Household Hunger Scale (HHS). IMT1B Using Stata (version 14.0; StataCorp LP, College Station, TX, USA), data analysis involved multilevel mixed-effects h a higher likelihood of HIV infection among OVC caregivers in Tanzania, suggesting that improving access to adequate food has a potential to reduce HIV risks among them. Furthermore, food insufficiency could be considered an important criterion for targeting HIV testing and treatment services to expand coverage.Tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS) in HIV-infected patients is the sign and symptom of exacerbation, or radiological manifestation of Mycobacterium tuberculosis (Mtb) infection, can describe the improvement of the immune system after initiating highly active antiretroviral therapy (HAART). No approved or explicit symptomatic tests for TB-IRIS exist, the diagnosis depends on the clinical manifestations. Here we report a TB-IRIS case with diagnostic challenges.

The aim of this paper was to review the current literature on cavity bases while focusing on the role of zinc oxide eugenol (ZOE) and resin-modified glass ionomers (RMGI) as cavity bases.

A thorough literature search between 1970 and 2020 was done using Scopus, PubMed, and Google Scholar databases. The keywords of the search strategy were as below cavity liners and bases, pulp protection, zinc oxide eugenol, and resin-modified glass ionomer. No specific inclusion or exclusion criteria were applied as to what articles would be included in this review.

This review emphasizes that the available literature provides very little evidence to support the routine use of a base under amalgam or composite restorations. This review favors the adoption of "no more lining or bases" in shallow and moderate cavity preparations. However, an exception might be a "protective base" of RMGI following the application of calcium hydroxide (CH) liners in deep cavities. Bonded RMGIs are suitable cavity base materials and should always replace zinc oxide eugenol bases in daily practice.

This review emphasizes that the available literature provides very little evidence to support the routine use of a base under amalgam or composite restorations. This review favors the adoption of "no more lining or bases" in shallow and moderate cavity preparations. However, an exception might be a "protective base" of RMGI following the application of calcium hydroxide (CH) liners in deep cavities. Bonded RMGIs are suitable cavity base materials and should always replace zinc oxide eugenol bases in daily practice.

Adenomatoid odontogenic tumor (AOT) is an uncommon benign odontogenic lesion with varied clinical and histological presentation. It has slow growth potential and a low recurrence rate. The tumor is mainly seen in females in the second decade of life, predominantly affecting the maxilla and associated most often with unerupted canine teeth, earning the epithet "two-thirds tumor". There are three variants intrafollicular, extrafollicular, and peripheral. The peripheral or extra osseous type is a rare form that arises in gingival tissue.

This article describes a case of AOT in a 10-year-old girl who presented with gingival enlargement in relation to the maxillary left central incisor. Interestingly, intraoral periapical radiography did not show any significant findings. However, cone-beam computed tomography of the site revealed significant bone loss in the area. A surgical excision was done. Histopathological examination revealed features of AOT. Based on clinical, radiographic, and histological evidence, a diagnosis of peripheral AOT (PAOT) was made.