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eolysis and decreased the length of hospitalization.

Patients in an ICU are particularly vulnerable to sepsis. It is therefore important to detect its onset as early as possible. This study focuses on the development and validation of a new signature-based regression model, augmented with a particular choice of the handcrafted features, to identify a patient's risk of sepsis based on physiologic data streams. The model makes a positive or negative prediction of sepsis for every time interval since admission to the ICU.

The data were sourced from the PhysioNet/Computing in Cardiology Challenge 2019 on the "Early Prediction of Sepsis from Clinical Data." It consisted of ICU patient data from three separate hospital systems. Algorithms were scored against a specially designed utility function that rewards early predictions in the most clinically relevant region around sepsis onset and penalizes late predictions and false positives.

The work was completed as part of the PhysioNet 2019 Challenge alongside 104 other teams.

PhysioNet sourced over 60,000 ICU patients with up to 40 clinical variables for each hour of a patient's ICU stay. The Sepsis-3 criteria was used to define the onset of sepsis.

None.

The algorithm yielded a utility function score which was the first placed entry in the official phase of the challenge.

The algorithm yielded a utility function score which was the first placed entry in the official phase of the challenge.

Therapeutic mammaplasty is a well-established advanced oncoplastic technique for larger tumors in large breasts. However, the larger the breasts are, the greater is the lower outer parenchymal displacement due to weight resulting in relative emptiness in the medial/cleavage part. Therefore, the default practice of excising the medial wing parenchymal component of Wise pattern (WP) incision may either maintain or worsen such anatomy.

We present a technical innovation to improve the standard WP technique instead of excision, the medial wing of the WP incision is deepithelized, and parenchyma is preserved to retain or augment bulk.

Between July 2015 and December 2018, a total of 16 patients (26 breasts) underwent a medial hemi-mastopexy. This technique seems to be safe, with minimal complications even after radiotherapy.

Although its use is limited in lower inner quadrant tumors, "medial hemi-mastopexy" can be safely applied to cancers located in all the other quadrants and potentially in the cosmetic setting as well. This case series is limited by the small numbers and short follow-up; however, the data show promising results.

Although its use is limited in lower inner quadrant tumors, "medial hemi-mastopexy" can be safely applied to cancers located in all the other quadrants and potentially in the cosmetic setting as well. This case series is limited by the small numbers and short follow-up; however, the data show promising results.

Promoting patient satisfaction is crucial for healthcare quality improvement. However, literature on patient satisfaction with nursing care in Ghana is limited. The aim of this study was to assess patient satisfaction with perioperative nursing care in Korle-Bu Teaching Hospital, the largest tertiary hospital in Ghana.

The study was a cross-sectional study. A sample of one hundred (

=100) in-patients in the surgical department were interviewed. Statistical Package for Social Science (SPSS), version 22, was used to analyze the data. The results were presented using univariate, bivariate and multivariate analyses.

It was found that majority of the respondents were males (53%), employed (56%) and insured (85%). It was also found that eight in ten respondents were satisfied with the perioperative nursing care. Tetrazolium Red compound library chemical Overall patient satisfaction with perioperative nursing care was significantly associated with information provision (

<0.001), nurse-patient relationship (

<0.001), fear and concern (

<0.05) and discomfort and need (

<0.05). At the multivariate level, overall patient satisfaction was significantly influenced by nurse-patient relationship (

=0.430,

=0.002).

There is limited literature on nursing care in surgical departments and rarely are patients' views considered in assessing quality of perioperative care, especially in Low- and Middle- Income Countries (LMICs). This study is a modest contribution to the literature on patient satisfaction with perioperative nursing care in Ghana.

There is limited literature on nursing care in surgical departments and rarely are patients' views considered in assessing quality of perioperative care, especially in Low- and Middle- Income Countries (LMICs). This study is a modest contribution to the literature on patient satisfaction with perioperative nursing care in Ghana.

To study the survival rate of patients without biochemical recurrence according to the Stuttgart and Phoenix criteria in terms of their correlation with four different PSA nadir values as predictors of clinical recurrence in patients with localized prostate cancer who underwent total HIFU prostate ablation.

The object of the study was patients with morphologically proven localized RP by biopsy results, who were treated with prostate cancer by HIFU ablation on the Ablatherm Integrated Imaging apparatus (EDAP TMS, France). The study included 658 patients in whom HIFU ablation was used as primary treatment of localized prostate cancer (stages T1 - T2) without previous use of other methods (hormonal, radiation therapy) For the analysis, a continuous sample of patients was selected, which were divided into four groups depending on the PSA nadir level less or equal 0.2 ng / ml (1 group), 0.21-0.5 ng / ml (group 2), 0.51-1 ng / ml (group 3) and> 1 ng / ml (group 4). sensitivity, specificity, predictive value,nical practice.

This study confirms that PSA nadir after HIFU ablation predicts biochemical recurrence-free survival and is a reliable marker that is easy to integrate into routine clinical practice.Urinary cytology (UC) is one of the primary diagnostic modalities used for the screening and surveillance of urothelial carcinoma. Despite its widespread use, UC has suffered from a lack of standardized or reproducible criteria and wide interobserver variability, particularly of the designation of atypical urothelial cells. The Paris System for Reporting Urinary Cytology (TPS), published in 2016, aimed to provide a standardized approach for evaluating UC by creating diagnostic categories with specific cytomorphologic criteria. Recent studies have primarily investigated the application of TPS on lower urinary tract specimens and have mostly shown that TPS implementation has improved the performance of UC specimens. Only a few studies have reported the impact of TPS on upper urinary tract (UUT) cytology. Additionally, there is uncertainty as to which cytological features are most predictive of high-grade urothelial carcinoma (HGUC) in the UUT. This review summarizes the literature regarding the utility and performance of UUT cytology and highlights findings before and after the implementation of TPS.