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Moreover, we show that for those properties # IndSub ( Φ ) can not be solved in time f ( k ) · n o ( k ) for any computable function f unless the Exponential Time Hypothesis (ETH) fails. In the final part of the paper, we investigate non-monotone properties and prove that # IndSub ( Φ ) is # W [ 1 ] -hard if Φ is any non-trivial modularity constraint on the number of edges with respect to some prime q or if Φ enforces the presence of a fixed isolated subgraph.Gas Chromatography/Differential Mobility Spectrometry (GC/DMS) is an effective tool to discern volatile chemicals. The process of correlating GC/DMS data outputs to chemical identities requires time and effort from trained chemists due to lack of commercially available software and the lack of appropriate libraries. This paper describes the coupling of computer vision techniques to develop models for peak detection and can align chemical signatures across datasets. The result is an automatically generated peak table that provides integrated peak areas for the inputted samples. The software was tested against a simulated dataset, whereby the number of detected features highly correlated to the number of actual features (r2 = 0.95). This software has also been developed to include random forests, a discriminant analysis technique that generates prediction models for application to unknown samples with different chemical signatures. In selleck chemicals llc described herein, the model achieves 3% classification error with 12 trees and 0% classification error with 48 trees. The number of trees can be optimized based on the computational resources available. We expect the public release of this software can provide other GC/DMS researchers with a tool for automated featured extraction and discriminant analysis capabilities.Human spaceflight and the characteristics of people who become astronauts have changed over time. Here we present an analysis of n=1,265 manned spaceflights by n=562 astronauts from 1961-2020 to investigate historical trends over time and between space agencies in terms of astronaut demographics and spaceflight duration. #link# Generalized linear models and generalized linear mixed models were implemented with adjustments for all available demographic data as covariates. Women continue to be underrepresented as astronauts, and were younger, had fewer children, and were less likely to have a military background than their male counterparts. Astronaut age has increased over time, although this increase was significant only for first-time spaceflights. The proportion of astronauts from civilian backgrounds has generally increased over time, although there is evidence this trend may be reversing. Spaceflight duration has increased over time, and has been longest for ROSCOSMOS cosmonauts and shortest for Chinese taikonauts. There were also differences between space agencies in terms of astronaut demographics, particularly between NASA and ROSCOSMOS, with first-time NASA astronauts more likely to be women, civilian and older than first-time ROSCOSMOS cosmonauts. As humankind embarks on exploration-class missions back to the lunar surface and then onward to Mars, and with new nations and commercial entities entering the international space community, the nature of spaceflight, and the diversity of the astronauts, will continue to evolve.Encapsulated within the temporal bone and comprising the smallest elements of the vertebrate skeleton, the ear is key to multiple senses balance, posture control, gaze stabilization, and hearing. The transformation of the primary jaw joint into the mammalian ear ossicles is one of the most iconic transitions in vertebrate evolution, but the drivers of this complex evolutionary trajectory are not fully understood. We propose a novel hypothesis The incorporation of the bones of the primary jaw joint into the middle ear has considerably increased the genetic, regulatory, and developmental complexity of the mammalian ear. This increase in the number of genetic and developmental factors may, in turn, have increased the evolutionary degrees of freedom for independent adaptations of the different functional ear units. The simpler ear anatomy in birds and reptiles may be less susceptible to developmental instabilities and disorders than in mammals but also more constrained in its evolution. Despite the tight spatial entanglement of functional ear components, the increased "evolvability" of the mammalian ear may have contributed to the evolutionary success and adaptive diversification of mammals in the vast diversity of ecological and behavioral niches observable today. A brief literature review revealed supporting evidence for this hypothesis.In 1907 Einstein had the insight that bodies in free fall do not "feel" their own weight. This has been formalized in what is called "the principle of equivalence." The principle motivated a critical analysis of the Newtonian and special-relativistic concepts of inertia, and it was indispensable to Einstein's development of his theory of gravitation. A great deal has been written about the principle. Nearly all of this work has focused on the content of the principle and whether it has any content in Einsteinian gravitation, but more remains to be said about its methodological role in the development of the theory. I argue that the principle should be understood as a kind of foundational principle known as a criterion of identity. This work extends and substantiates a recent account of the notion of a criterion of identity by William Demopoulos. Demopoulos argues that the notion can be employed more widely than in the foundations of arithmetic and that we see this in the development of physical theories, in particular space-time theories. This new account forms the basis of a general framework for applying a number of mathematical theories and for distinguishing between applied mathematical theories that are and are not empirically constrained.Primitive objects like comets hold important information on the material that formed our solar system. Several comets have been visited by spacecraft and many more have been observed through Earth- and space-based telescopes. Still our understanding remains limited. Molecular abundances in comets have been shown to be similar to interstellar ices and thus indicate that common processes and conditions were involved in their formation. The samples returned by the Stardust mission to comet Wild 2 showed that the bulk refractory material was processed by high temperatures in the vicinity of the early sun. The recent Rosetta mission acquired a wealth of new data on the composition of comet 67P/Churyumov-Gerasimenko (hereafter 67P/C-G) and complemented earlier observations of other comets. The isotopic, elemental, and molecular abundances of the volatile, semi-volatile, and refractory phases brought many new insights into the origin and processing of the incorporated material. The emerging picture after Rosetta is that at least part of the volatile material was formed before the solar system and that cometary nuclei agglomerated over a wide range of heliocentric distances, different from where they are found today. Deviations from bulk solar system abundances indicate that the material was not fully homogenized at the location of comet formation, despite the radial mixing implied by the Stardust results. Post-formation evolution of the material might play an important role, which further complicates the picture. This paper discusses these major findings of the Rosetta mission with respect to the origin of the material and puts them in the context of what we know from other comets and solar system objects.The large field-of-view of the Sun Watcher using Active Pixel System detector and Image Processing (SWAP) instrument onboard the PRoject for Onboard Autonomy 2 (PROBA2) spacecraft provides a unique opportunity to study extended coronal structures observed in the EUV in conjunction with global coronal magnetic field simulations. A global non-potential magnetic field model is used to simulate the evolution of the global corona from 1 September 2014 to 31 March 2015, driven by newly emerging bipolar active regions determined from Helioseismic and Magnetic Imager (HMI) magnetograms. We compare the large-scale structure of the simulated magnetic field with structures seen off-limb in SWAP EUV observations. In particular, we investigate how successful the model is in reproducing regions of closed and open structures, the scale of structures, and compare the evolution of a coronal fan observed over several rotations. The model is found to accurately reproduce observed large-scale, off-limb structures. When discrepancies do arise they mainly occur off the east solar limb due to active regions emerging on the far side of the Sun, which cannot be incorporated into the model until they are observed on the Earth-facing side. When such "late" active region emergences are incorporated into the model, we find that the simulated corona self-corrects within a few days, so that simulated structures off the west limb more closely match what is observed. link2 Where the model is less successful, we consider how this may be addressed, through model developments or additional observational products.

The online version of this article (10.1007/s11207-020-01668-2) contains supplementary material, which is available to authorized users.

The online version of this article (10.1007/s11207-020-01668-2) contains supplementary material, which is available to authorized users.Lack of good-quality planting materials has been identified as the most severe problem militating against increased agricultural productivity in sub-Saharan Africa (SSA) and beyond. However, investment of research efforts and resources in addressing this menace will only be feasible and worthwhile if attendant economic gains are considerable. As a way of investigating the economic viability of yam investment, this research has been initiated to address problems confronting yam productivity in eight countries of SSA and beyond Nigeria, Ghana, Benin, Togo, Côte d'Ivoire, Papua New Guinea, Jamaica, and Columbia. Research options developed were to be deployed and disseminated. Key technologies include the adaptive yam minisett technique (AYMT), varieties adapted to low soil fertility and drought, nematode-resistant cultivars (NRC), and crop management and postharvest practices (CMPP). This article aims at estimating the potential economic returns, the expected number of beneficiaries, and poverty reduction consequent to the adoption of technology options. link3 Estimates show that the new land area that will be covered by the technologies in the eight countries will range between 770,000 ha and 1,000,000 ha with the highest quota accounted for by AYMT. The net present value will range between US$584 and US$1392 million and was highest for the NRC. The CMPP had the lowest benefit-cost ratio of 7.74. About 1,049,000 people would be moved out of poverty by these technologies by 2037 in the region. These technologies are less responsive to changes in cost than that in adoption rate. Therefore, the realization of the potential economic gains depends on the rate and extent of adoption of these technologies. Giving the knowledge-intensive nature of some of these interventions, capacity building of potential adopters will be critical to increasing the sustainability of the yam sector, thereby enhancing food security and reducing poverty.

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