Mccarthyvognsen9916

5% and 66%. The non-invasive TFO system was able to accurately measure these fetal SpO2 values, supported by a root mean-squared error of 6.37% and strong measures of agreement with the gold standard.

The results support the efficacy of the presented TFO system to non-invasively measure a wide-range of fetal SpO2 values and identify critical levels of fetal hypoxia.

TFO has the potential to improve fetal outcomes by providing obstetricians with a non-invasive measure of fetal oxygen saturation prior to delivery.

TFO has the potential to improve fetal outcomes by providing obstetricians with a non-invasive measure of fetal oxygen saturation prior to delivery.Acute ischemic stroke is a major health problem with a high mortality rate and a high risk for permanent disabilities. Selective brain hypothermia has the neuroprotective potential to possibly lower cerebral harm. A recently developed catheter system enables to combine endovascular blood cooling and thrombectomy using the same endovascular access. By using the penumbral perfusion via leptomeningeal collaterals, the catheter aims at enabling a cold reperfusion, which mitigates the risk of a reperfusion injury. However, cerebral circulation is highly patient-specific and can vary greatly. Since direct measurement of remaining perfusion and temperature decrease induced by the catheter is not possible without additional harm to the patient, computational modeling provides an alternative to gain knowledge about resulting cerebral temperature decrease. In this work, we present a brain temperature model with a realistic division into gray and white matter and consideration of spatially resolved perfusion. Furthermorence of direct intraparenchymal temperature probes.

7-Tesla MRI of the hippocampus enhances the visualization of its internal substructures. Among these substructures, the cornu Ammonis and subiculum form a contiguous folded ribbon of gray matter. Here, we propose a method to analyze local thickness measurements of this ribbon.

We introduce an original approach based upon the estimation of a diffeomorphic vector field that traverses the ribbon. The method is designed to handle specificities of the hippocampus and corresponding 7-Tesla acquisitions highly convoluted surface, non-closed ribbon, incompletely defined inner/outer boundaries, anisotropic acquisitions. We furthermore propose to conduct group comparisons using a population template built from the central surfaces of individual subjects.

We first assessed the robustness of our approach to anisotropy, as well as to inter-rater variability, on a post-mortem scan and on in vivo acquisitions respectively. We then conducted a group study on a dataset of in vivo MRI from temporal lobe epilepsy (TLE) pa3533264).

The zebrafish has been proven to be a significant model organism in various research fields. MS023 For investigating the in vivo properties of biologics within zebrafish with developed organs, an automated zebrafish larva organ injection system is crucially needed. However, current zebrafish larva manipulation techniques cannot accomplish this operation efficiently and continuously.

In this paper, we present a novel zebrafish larva manipulation technique with two key steps in the microinjection system orienting and aspirating zebrafish larvae automatically. The orientation control is realized in a customized microfluidic chip, after which the larva moves tail-first until reaching the channel exit. Then a dynamic model of larva aspiration is established and an adaptive robust controller is designed.

Experimental results demonstrate that high success rate can be reached and damage to larva body is reduced.

The presented strategy is capable of orienting and aspirating zebrafish larvae smoothly and efficiently.

The proposed methods have the advantage of low cost, easy implementability and good stability.

The proposed methods have the advantage of low cost, easy implementability and good stability.Ultrasound-guided procedures have been applied in many clinical therapies, such as cardiac catheterization and regional anesthesia. Medical instrument detection in 3D Ultrasound (US) is highly desired, but the existing approaches are far from real-time performance. Our objective is to investigate an efficient instrument detection method in 3D US for practical clinical use. We propose a novel Multi-dimensional Mixed Network for efficient instrument detection in 3D US, which extracts the discriminating features at 3D full-image level by a 3D encoder, and then applies a specially designed dimension reduction block to reduce the spatial complexity of the feature maps by projecting from 3D space into 2D space. A 2D decoder is adopted to detect the instrument along the specified axes. By projecting the predicted 2D outputs, the instrument is detected or visualized in the 3D volume. Furthermore, to enable the network to better learn the discriminative information, we propose a multi-level loss function to capture both pixel- and image-level differences. We carried out extensive experiments on two datasets for two tasks (1) catheter detection for cardiac RF-ablation and (2) needle detection for regional anesthesia. Our experiments show that our proposed method achieves a detection error of 2-3 voxels with an efficiency of about 0.12 sec per 3D US volume. The proposed method is 3-8 times faster than the state-of-the-art methods, leading to real-time performance. The results show that our proposed method has significant clinical value for real-time 3D US-guided intervention.Skin temperature has long been used as a natural indicator of vascular diseases in the extremities. Considerable correlation between oscillations in skin surface temperature and oscillations of skin blood flow has previously been demonstrated. We hypothesised that the impairment of blood flow in stenotic (subcutaneous) peripheral arteries would influence cutaneous temperature such that, by measuring gradients in the temperature distribution over skin surfaces, one may be able to diagnose or quantify the progression of vascular conditions in whose pathogenesis a reduction in subcutaneous blood perfusion plays a critical role (e.g. peripheral artery disease). As proof of principle, this study investigates the local changes in the skin temperature of healthy humans (15 male, [Formula see text] years old, BMI [Formula see text] kg/m 2) undergoing two physical challenges designed to vary their haemodynamic status. Skin temperature was measured in four central regions (forehead, neck, chest, and left shoulder) and four peripheral regions (left upper arm, forearm, wrist, and hand) using an infrared thermal camera.