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For C glabrata, there was no statistical difference between the solutions (P = .264). For Co-Cr, ET showed the highest level of antimicrobial action against all microorganisms (P < .001), and CH showed an intermediate level of action against S mutans and S aureus. Against C albicans and C glabrata, there was no significant difference among CH, CN, and WC.

Although ET had a broader spectrum of antimicrobial action, the chitosan solution showed promise as a denture cleanser.

Although ET had a broader spectrum of antimicrobial action, the chitosan solution showed promise as a denture cleanser.

To evaluate the effects of overnight storage conditions on the dimensional stability and retention of prostheses, as well as the participant's subjective perception of these interventions.

Subjects with maxillary complete prostheses (CRPs) were randomly assigned to receive two interventions in a crossover design storing the CRPs overnight in a dry or wet environment with a cleansing tablet. The denture intaglio surface was scanned, and outcome measures were collected before each intervention (BLN), post ntervention (PIS), and after immersion in water for 15 minutes after the intervention (WOC). Dimensional changes were analyzed for the total surface, anterior flange, palate, and tuberosities. Retention force was measured using a dynamometer, and the participants' subjective assessment of comfort, fit, and retention of their CRPs were collected. After verifying normal distribution, paired t and Wilcoxon signed-rank tests were used to check for any statistical significance (α = .05).

Ten participants (mean age 76.5 ± 5.9 y) were recruited in this study. VX-478 Between BLN and PIS, the dimensional changes after dry intervention were significantly less than when stored wet for total surface (P = .009), anterior flange (P = .028), and the palate (P = .005). No difference was found between the effects of storage or washout interventions on objectively measured CRP retention. However, after WOC following dry storage, participants perceived a lower retention (P = .021), and a more comfortable palate after WOC following the wet intervention (P = .018).

For dimensional stability, dry overnight storage of removable prostheses can safely be recommended when indicated. Immersion in water for 15 minutes does not seem to add advantages.

For dimensional stability, dry overnight storage of removable prostheses can safely be recommended when indicated. Immersion in water for 15 minutes does not seem to add advantages.

To determine the effects of tooth brushing on the surface roughness (Sa) and morphology, maximum relative depth (Rv), gloss (GU), and microhardness (MH) of four esthetic restorative materials and enamel.

A light-curing composite resin (Filtek Supreme Ultra [FSU], 3M ESPE), two hybrid resin/ceramic CAD/CAM materials (Lava Ultimate [LAV], 3M ESPE, and VITA Enamic [VEN], VITA Zahnfabrik), and a CAD/CAM feldspathic ceramic (VITA Blocs Mark II [VMA], VITA Zahnfabrik) were evaluated. Bovine enamel (ENA) was used as a control group. All surfaces were polished in accordance with the manufacturer's instructions. Samples were analyzed before and after brushing (30,000 cycles) regarding Sa and Rv using a 3D laser-measuring microscope. GU was evaluated every 10,000 tooth brushing cycles. MH was also measured before and after tooth brushing. The surfaces were observed using scanning electron and laser measuring microscopies to determine the wear patterns. Data were analyzed by paired t test, one-way or two-way repeated measures analysis of variance, and Tukey test (α = .05), depending on the method performed.

The Sa increased significantly after brushing for all materials, except for VMA, which showed the opposite effect. ENA and VEN showed higher Rv than VMA. After 30,000 tooth brushing cycles, VMA showed the highest GU, while FSU showed the lowest. Also, little surface topography changes were observed for VMA. MH did not change significantly after 30,000 brushing cycles, except for LAV.

Brushing caused surface alterations in all tested materials except for feldspathic ceramic. The changes were more evident in resin-based materials.

Brushing caused surface alterations in all tested materials except for feldspathic ceramic. The changes were more evident in resin-based materials.

To evaluate the readability and quality of patient-oriented information online among different common prosthodontic search areas using multiple quality and readability assessment tools.

The prosthodontic keywords most commonly searched by patients on the internet were included. The search was performed through two online search engines (Google and Yahoo) to create the study sample. The first 50 websites listed by each search engine were chosen for each keyword. The quality of each website's information was evaluated using the DISCERN questionnaire and the Health on the Net (HON) criteria. Readability assessment was performed using the Flesch-Kinkaid Reading Grade Level (FKRGL) and the Flesch Reading Ease Score (FRES).

A total of 225 websites were included in the study. The median score for the DISCERN instrument indicated poor information quality. A significant difference was found between the educational and commercial websites in both quality and readability. Overall, the median readability indices showed that the websites' information was difficult to read.

Internet-based health information on different prosthodontic treatments is difficult to read and poor in quality and readability. It is necessary for health care providers to establish and promote websites that have reliable, high-quality information about common prosthodontic treatments.

Internet-based health information on different prosthodontic treatments is difficult to read and poor in quality and readability. link2 It is necessary for health care providers to establish and promote websites that have reliable, high-quality information about common prosthodontic treatments.

To analyze the current evidence on the impact of surface finishing protocols (such as manual polishing or glazing) on the color stability of in vitro simulated pigmentation of CAD/CAM ceramics.

Five electronic databases were searched on February 12, 2020. In vitro experimental studies were included based on the following strategy intervention = surface treatment of CAD/CAM ceramics with glazing agents; comparison = surface treatment of CAD/CAM ceramics with manual polishing; and outcomes = color stability. Two reviewers independently assessed the risk of bias.

Among 1,390 articles that were screened, 6 in vitro studies were considered for qualitative analysis. Five articles confirmed changes in the color of ceramics when they were immersed in pigmented solutions. One article investigated the color stability of the samples via ultraviolet (UV) aging. Among the 6 studies analyzed, 4 showed clinically acceptable color alteration values represented by ΔE irrespective of the finishing protocol applied (glazing or mechanical polishing). link3 Two articles presented clinically unsatisfactory color variation (ΔE > 3.3 and ΔE > 2.7) following mechanical polishing of a zirconia-reinforced lithium silicate ceramic. Coffee and red wine proved to be the beverages with the greatest potential for ceramic pigmentation. Only 1 article had a high risk of bias.

For clinicians, most of the studies demonstrated that both manual polishing and glaze application can prevent significant color alterations on CAD/CAM ceramic surfaces. However, due to the relatively limited amount of evidence to support this conclusion, further studies must be conducted.

For clinicians, most of the studies demonstrated that both manual polishing and glaze application can prevent significant color alterations on CAD/CAM ceramic surfaces. However, due to the relatively limited amount of evidence to support this conclusion, further studies must be conducted.

We performed a systematic review and meta-analysis to evaluate the impact of 18F-FDG PET, PET/CT, and PET/MRI on staging and management during the initial staging of breast cancer.

We searched the PubMed, Embase, Cochrane Library, and KoreaMed databases until March 2020 to identify studies that reported the proportion of breast cancer patients whose clinical stage or management were changed after PET scans. The proportion of changes was pooled using a random-effects model. Subgroup and metaregression analyses were performed to explore heterogeneity.

We included 29 studies (4276 patients). The pooled proportions of changes in stage and management were 25% (95% confidence interval [CI], 21%-30%) and 18% (95% CI, 14%-23%), respectively. When stage changes were stratified according to initial stage, the pooled proportions were 11% (95% CI, 3%-22%) in stage I, 20% (95% CI, 16%-24%) in stage II, and 34% (95% CI, 27%-42%) in stage III. The relative proportions of intermodality and intention-to-treat changes were 74% and 70%, respectively. Using metaregression analyses, the mean age and the proportion of initial stage III to IV and histologic grade II to III were significant factors affecting the heterogeneity in changes in stage or management.

Currently available literature suggests that the use of 18F-FDG PET, PET/CT, or PET/MRI leads to significant modification of staging and treatment in newly diagnosed breast cancer patients. Therefore, there may be a role for routine clinical use of PET imaging for the initial staging of breast cancer.

Currently available literature suggests that the use of 18F-FDG PET, PET/CT, or PET/MRI leads to significant modification of staging and treatment in newly diagnosed breast cancer patients. Therefore, there may be a role for routine clinical use of PET imaging for the initial staging of breast cancer.

Occipital neuralgia (ON) is a primary headache disorder characterized by severe, paroxysmal, shooting or stabbing pain in the distribution of the greater occipital, lesser occipital, and/or third occipital nerves. Both medical and surgical options exist for treating headaches related to ON. The purposes of this study are to summarize the current state of surgical ON management through a systematic review of the literature and, in doing so, objectively identify future directions of investigation.

We performed a systematic review of primary literature on surgical management for ON of at least level IV evidence. Included studies were analyzed for level of evidence, therapeutic intervention, study design, sample size, follow-up duration, outcomes measured, results, and risk of bias.

Twenty-two studies met the inclusion criteria. All 22 studies used patient-reported pain scores as an outcome metric. Other outcome metrics included complication rates (7 studies; 32%), patient satisfaction (7 studies; 32%), quality of life (7 studies; 18%), and analgesic usage (3 studies; 14%). Using the ROBINS-I tool for risk of bias in nonrandomized studies, 7 studies (32%) were found to be at critical risk of bias, whereas the remaining 15 studies (68%) were found to be at serious risk of bias.

Greater occipital nerve decompression seems to be a useful treatment modality for medically refractory ON, but further prospective, randomized data are required.

Greater occipital nerve decompression seems to be a useful treatment modality for medically refractory ON, but further prospective, randomized data are required.

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