Mathiasenwind0719

1%,

 = 344) with proximal left anterior descending lesion (88%,

 = 432). Our study showed no differences between female and male patients regarding choice of conduits, number of anastomosed vessels, and outcome. Acute kidney injury (AKI) occurred significantly more often in female patients and pericardial tamponade in their male counterparts. There were no differences regarding other major complications.

Gender does not appear to influence long-term outcomes in the study sample. Female gender is an independent risk factor for postoperative AKI. Other complications occurred with comparable rates in both genders. Exertion tolerance in the follow-up period was similar between genders.

Gender does not appear to influence long-term outcomes in the study sample. Female gender is an independent risk factor for postoperative AKI. Other complications occurred with comparable rates in both genders. Exertion tolerance in the follow-up period was similar between genders.

We aimed to compare the surgical outcome between total arch replacement with coronary bypass surgery and that without.

Between 2008 and 2016, 157 consecutive patients underwent total arch replacement with antegrade cerebral perfusion and moderate hypothermic circulatory arrest using the proximal first approach. They were divided into two groups total arch replacement with coronary bypass surgery (group 1,

 = 38) and that without (group 2,

 = 119).

Of the 38 patients in group 1, 37 (97%) were asymptomatic. The left internal thoracic artery and saphenous vein were used in one (2.6%) and 38 (100%) patients, respectively. The mean number of coronary anastomoses was 1.5 ± 1.0. In-hospital mortality rate was 3.8%. Cardiopulmonary bypass time and operation time in group 1 were significantly longer than those in group 2 (336 ± 52min vs. 276 ± 38min,

 < 0.0001 and 702 ± 122min vs. 619 ± 94min,

 < 0.0001, respectively). No differences in in-hospital mortality and perioperative myocardial infarction were found between the groups (5.3% vs. 3.4%,

 = 0.633 and 0% vs. 1.7%,

 = 1.000, respectively). In the multivariate analysis, age (odds ratio, 1.208; 95% confidence interval, 1.041-1.497;

 = 0.008) and cardiopulmonary bypass time (odds ratio, 1.019; 95% confidence interval, 1.001-1.041;

 = 0.041) were significant determinants of in-hospital mortality.

Although prolonged cardiopulmonary bypass time was a significant determinant of in-hospital mortality, total arch replacement with coronary bypass surgery could be safely performed with favorable outcomes.

Although prolonged cardiopulmonary bypass time was a significant determinant of in-hospital mortality, total arch replacement with coronary bypass surgery could be safely performed with favorable outcomes.

Mitral valve annuloplasty has evolved over the decades since its introduction and Carpentier played a major role in developing the technique. Mitral valve repair is preferred over replacement for severe primary mitral regurgitation, as it restores normal life expectancy when successful and does not require lifelong anticoagulation. There is an ongoing debate regarding the choice of ring for mitral valve annuloplasty-rigid or flexible. At present, the choice of ring is based on the availability of the ring and left to the surgeon's discretion.

This is a retrospective study conducted at a tertiary referral centre.

To compare the outcomes of mitral valve repair annuloplasty with flexible and rigid rings. compound library chemical The hospital records of 112 patients who underwent mitral valve annuloplasty between January 2010 and December 2014 at our hospital were studied. All patients were followed up for 5years. The rigid and flexible groups were compared for left ventricular (LV) size regression and the presence of mitral regurgd ring group and the difference is not statistically significant (

value 0.314). The mean LVIDD size regression at 5years was 10.62 ± 6.57mm in the flexible ring group and 9.38 ± 9.29mm in the rigid ring group and the difference is not statistically significant (

value 0.408).

The choice of rigid or flexible ring did not have a marked difference on the outcome of mitral valve annuloplasty at midterm follow-up.

The choice of rigid or flexible ring did not have a marked difference on the outcome of mitral valve annuloplasty at midterm follow-up.Health Heatmap of India is an open data platform built for bringing together data from diverse sources and facilitating visualization, analysis, and insight building from such data. In this paper, we describe the context and need for such an open data platform and describe the technical aspects of building it. The beta site of the portal is available at https//healthheatmapindia.org.As SARS-CoV-2 continues to propagate around the world, it is becoming increasingly important to scale up testing. This is necessary both at the individual level, to inform diagnosis, treatment and contract tracing, as well as at the population level to inform policies to control spread of the infection. The gold-standard RT-qPCR test for the virus is relatively expensive and takes time, so combining multiple samples into "pools" that are tested together has emerged as a useful way to test many individuals with less than one test per person. Here, we describe the basic idea behind pooling of samples and different methods for reconstructing the result for each individual from the test of pooled samples. The methods range from simple pooling, where each pool is disjoint from the other, to more complex combinatorial pooling where each sample is split into multiple pools and each pool has a specified combination of samples. We describe efforts to validate these testing methods clinically and the potential advantages of the combinatorial pooling method named Tapestry Pooling that relies on compressed sensing techniques.Presently world is on a war with the novel coronavirus and with no immediate treatments available the scourge caused by the SARS-CoV-2 is increasing day by day. A lot of researches are going on for the potential drug candidate that could help the healthcare system in this fight. Plants are a natural data bank of bioactive compounds. Many phytochemicals are being studied for various ailments including cancer, bacterial and viral infections, etc. The present study aims to screen 38 bioactive compounds from 5 selected plants viz., Azadirachta indica, Curcuma longa, Zingiber officinale, Ocimum basilicum and Panax ginseng against SARS-CoV-2. Lipinski's rule was taken as the foundation for initial screening. Shortlisted compounds were subjected to molecular docking study with Mpro receptor present in SARS-CoV-2. The study identified that gedunin, epoxyazadiradione, nimbin and ginsenosides have potential to inhibit Mpro activity and their binding energies are - 9.51 kcal/mol, - 8.47 kcal/mol, - 8.66 kcal/mol and - 9.63 kcal/mol respectively. Based on bioavailability radar studies gedunin and epoxyazadiradione are the two most potent compounds which are used for molecular dynamics simulation studies. Molecular dynamics studies showed that gedunin is more potent than epoxyazadiradione. To find the effectiveness and to propose the exact mechanism, in-vitro studies can be further performed on gedunin.A thermoplastic elastomer (TPE) based nanocomposite with the same weight ratio of hybrid nanofillers composed of carbon nanotubes (CNTs) and montmorillonite nanoclay (DK4) was prepared using a melt blending technique with an internal mixer. The TPE composite was blended from polylactic acid (PLA), liquid natural rubber (LNR) as a compatibilizer and natural rubber (NR) in a volume ratio of 701020, respectively. The weight ratio of CNTs and DK4 was 2.5 wt%. The prepared samples were exposed to gamma radiation at range of 0-250 kGy. After exposure to gamma radiation, the mechanical, thermo-mechanical, thermal and electrical conductivity properties of the composites were significantly higher than unirradiated TPE composites as the irradiation doses increased up to 150 kGy. Transmission electron microscopy (TEM) micrographs revealed the good distribution and interaction between the nano-fillers and the matrix in the prepared TPE hybrid nanocomposites. In summary, the findings from this work definite that gamma irradiation might be a viable treatment to improve the properties of TPE nanocomposite for electronic packaging applications.

To study the agreement between proton microdosimetric distributions measured with a silicon-based cylindrical microdosimeter and a previously published analytical microdosimetric model based on Geant4-DNA in-water Monte Carlo simulations for low energy proton beams.

Distributions for lineal energy (

) are measured for four proton monoenergetic beams with nominal energies from 2.0 MeV to 4.5 MeV, with a tissue equivalent proportional counter (TEPC) and a silicon-based microdosimeter. The actual energy for protons traversing the silicon-based microdosimeter is simulated with SRIM. Monoenergetic beams with these energies are simulated with Geant4-DNA code by simulating a water cylinder site of dimensions equal to those of the microdosimeter. The microdosimeter response is calibrated by using the distribution peaks obtained from the TEPC. Analytical calculations for











y





¯







F







and











y









D







with our analytical method.

Simulations in Geant4-DNA with ideal cylindrical sites in liquid water produce similar results to the measurements in an actual silicon-based cylindrical microdosimeter properly calibrated. The found agreement suggests the possibility to experimentally verify the calculated clinical y ¯ D with our analytical method.The "First-Last Mile" problem (FLM) is a relevant transport issue. According to the Green Paper on Urban Mobility, the combination of passenger and freight flows may be a valid approach to promote sustainable, efficient and socially desirable FLM transport. This paper proposes a set of key performance indicators to evaluate potential improvements in operational, environmental and social performances of integrated passenger and freight flows, compared to the current transport schemes. The two case studies of the Northern lagoon of Venice in Italy and the Slovenian Municipality of Velenje indicate that the model may be particularly effective in those cases where reduced freight volumes, limited freight pickup/delivery locations and a lower elasticity of the travel demand reduce the constraints to the adoption of this integrated scheme. Results call for a reduction both in distances travelled and in externalities produced, and hence a good potential in FLM terms. Beside these technical aspects, one of the main issues is the need for innovation in the normative/regulatory context a prerequisite in order to apply this solution to real-life contexts.In this paper, we analyze a stochastic coronavirus (COVID-19) epidemic model which is perturbed by both white noise and telegraph noise incorporating general incidence rate. Firstly, we investigate the existence and uniqueness of a global positive solution. Then, we establish the stochastic threshold for the extinction and the persistence of the disease. The data from Indian states, are used to confirm the results established along this paper.