Magnussenshaw4199
Alcohol measurement delivered by health care providers in primary health care settings is an efficacious and cost-effective intervention to reduce alcohol consumption among patients. However, this intervention is not yet routinely implemented in practice. Community support has been recommended as a strategy to stimulate the delivery of alcohol measurement by health care providers, yet evidence on the effectiveness of community support in this regard is scarce. The current study used a pre-post quasi-experimental design in order to investigate the effect of community support in three Latin American municipalities in Colombia, Mexico, and Peru on health care providers' rates of measuring alcohol consumption in their patients. The analysis is based on the first 5 months of implementation. Moreover, the study explored possible mechanisms underlying the effects of community support, through health care providers' awareness of support, as well as their attitudes, subjective norms, self-efficacy, and subsequent inte Registration ID NCT03524599; Registered 15 May 2018; https//clinicaltrials.gov/ct2/show/NCT03524599.
Surgical robots have multiple manipulators with complex mechanisms and need to work in a narrow space in the patient's body. Therefore, for robot-assisted minimally invasive surgery (RMIS), it is very important to develop a reasonable preoperative planning before surgery.
A preoperative planning method based on the premise of no collision between surgical instruments and endoscope, an evaluation index with visibility, operability and hand-eye coordination was proposed in this paper. To consider the balance relationship of global optimization index, a multi-objective particle swarm optimization (MOPSO) algorithm was adopted. Because the physical characteristics of each patient are different, the method can determine the selectable area of the incision based on the relevant knowledge of anatomy.
The simulation taking the cholecystectomy as an example was performed on a minimally invasive surgical robotic system. The analysis result showed that the proposed preoperative planning method based on the MOPSO could provide surgeons with a reasonable and effective preoperative planning.
The proposed preoperative planning method based on the MOPSO is suitable for patients with different physical characteristics, and can provide a guidance for surgeons and effectively reduce the preoperative planning time and improve the safety and efficiency of the operation, especially a novice surgeon who lacks robot-assisted minimally invasive surgery experience.
The proposed preoperative planning method based on the MOPSO is suitable for patients with different physical characteristics, and can provide a guidance for surgeons and effectively reduce the preoperative planning time and improve the safety and efficiency of the operation, especially a novice surgeon who lacks robot-assisted minimally invasive surgery experience.
Theileriosis and babesiosis, two tick-borne haemoparasitic diseases (TBHDs) of ruminants, are caused by protozoan parasites of the genus Theileria and Babesia, respectively. Among them, some species are considered to be highly pathogenic causing serious economic losses to livestock holders especially in tropic and subtropic regions. Local and/or general control measures are needed to be applied to reduce economic impact of TBHDs. Prevalence studies are essential for the implementation and/or design of effective prevention and control measures based on true epidemiological data. Therefore, this study aimed to investigate the presence, prevalence and possible cross infections of Theileria/Babesia species between sheep, goat and cattle herds in Burdur province in Turkey.
A total of 964 blood samples were collected from sheep (n = 330), goat (n = 300) and cattle (n = 334) from five different districts of Burdur province. The samples were investigated for ovine and bovine Theileria/Babesia species using reverse line blot (RLB) hybridization assay.
In small ruminants, T.ovis was the most abundant Theileria species detected in sheep with a rate of 79.69%. Among Babesia species, B.ovis and B.crassa were detected only in blood of goats (0.66%) and sheep (1.12%) as single and mixed infections, respectively. In cattle, T.annulata, B.bovis, Babesiaspp. were detected in rates of 0.59%, 3.29%, 3.59%, respectively.
Obtained results clearly indicated that no cross infections with Theileria/Babesia species occurred in small ruminant and cattle herds that use the same grazing area.
Obtained results clearly indicated that no cross infections with Theileria/Babesia species occurred in small ruminant and cattle herds that use the same grazing area.Clustering methods based on environmental variables are useful in the planning of conservation strategies for species and ecosystems. However, there is a lack of work on the regionalization of the vast space of North Africa and the distribution of plant species. The current lists of endemic plants are focused mostly on an occurrence at the country level and not on regions with different conditions. The aim of this work was to lay out an environmental scheme for northwest Africa and to collect data about the occurrence of endemic plants in this area. Clustering with 12 of 33 tested environmental rasters was performed to divide the Maghreb into environmental clusters. Then, a list of 1618 endemic plant taxa (1243 species and 375 subspecies) was prepared and their distribution in estimated environmental clusters was examined. Eleven clusters with different conditions were estimated. The main drivers of regionalization were temperature amplitude, precipitation seasonality, and precipitation of the warmest quarter. According to the occurrence of endemic plants, northwest Africa may be divided into three zones Atlas, Mediterranean (two environmental clusters), and southern zone (eight environmental clusters). The presented results provide a good basis for understanding the spatial patterns of the Maghreb, including its environment and species diversity. A designed list of endemic plant species together with environmental data may facilitate the planning of future research in north Africa and arranging methods of biodiversity protection.
To determine whether racial/ethnic differences in patient experiences with care, potentially leading to underutilization of necessary care, are associated with disparities in Gleason score at diagnosis.
We used the SEER-CAHPS linked dataset to identify Medicare beneficiaries who completed a Consumer Assessment of Healthcare Providers and Systems (CAHPS) survey prior to diagnosis of prostate cancer. Independent variables included aspects of patient experiences with care captured by CAHPS surveys. We conducted survey weighted multivariable multinomial logistic regression analyses, stratified by patient race/ethnicity, to estimate associations of CAHPS measures with Gleason score at diagnosis.
Of the 4,245 patients with prostate cancer, most were non-Hispanic white (NHW) (77.6%), followed by non-Hispanic black (NHB) (8.4%), Hispanic (8.4%), and Asian (5.6%). Excellent experience with getting needed prescription drugs was associated with lower odds of Gleason scores of 7 and 8-10 in NHBs (7 OR = 0.19, 95% Cparities and improve patient outcomes.Networks based on carbon nanotube (CNT) have been widely utilized to fabricate flexible electronic devices, but defects inevitably exist in these structures. In this study, we investigate the influence of the CNT-unit defects on the mechanical properties of a honeycomb CNT-based network, super carbon nanotube (SCNT), through molecular dynamics simulations. Results show that tensile strengths of the defective SCNTs are affected by the defect number, distribution continuity and orientation. Single-defect brings 0 ~ 25% reduction of the tensile strength with the dependency on defect position and the reduction is over 50% when the defect number increases to three. The distribution continuity induces up to 20% differences of tensile strengths for SCNTs with the same defect number. A smaller arranging angle of defects to the tensile direction leads to a higher tensile strength. Defective SCNTs possess various modes of stress concentration with different concentration degrees under the combined effect of defect number, arranging direction and continuity, for which the underlying mechanism can be explained by the effective crack length of the fracture mechanics. Fundamentally, the force transmission mode of the SCNT controls the influence of defects and the cases that breaking more force transmission paths cause larger decreases of tensile strengths. Defects are non-negligible factors of the mechanical properties of CNT-based networks and understanding the influence of defects on CNT-based networks is valuable to achieve the proper design of CNT-based electronic devices with better performances.Street dust samples can be used as an indicator for pollution monitoring especially in big cities. Various environmental problems have been experienced in Dilovasi, Turkey, and studies have been carried out in many different areas; however, no study has been conducted to examine the heavy metal content in street dusts. Therefore, in this study, 20 heavy metals, namely Si, Fe, Al, Zn, Mn, Ti, Cr, Ba, Pb, Ni, Sr, V, Co, Cd, Sb, As, Sn, Mo, Sc and Ag, in the street dusts of Dilovasi were investigated at 40 sampling points. Samples were analyzed with ICP-MS and ICP-OES. The concentrations were from 0.01 mg/kg for Ag to 42,645.48 mg/kg for Si. The Igeo values were in the range of 0.02 for Ag and 8.03 for V. The average EF value was 29.67, which indicates a very high pollution level. ERI was found as 300.74. This value being 300-600 indicates a considerable ecological risk level for the region. selleck inhibitor According to PCA, the predominant anthropogenic contribution of metal pollution in this area was due to traffic and vehicle-related activities and industrial activities and their waste. Metal pollution from residential areas and natural resources was relatively low, but it was another source of pollution.Pyrophosphate-containing calcium phosphate implants promote osteoinduction and bone regeneration. The role of pyrophosphate for inflammatory cell-mesenchymal stem cell (MSC) cross-talk during osteogenesis is not known. In the present work, the effects of lipopolysaccharide (LPS) and pyrophosphate (PPi) on primary human monocytes and on osteogenic gene expression in human adipose-derived MSCs were evaluated in vitro, using conditioned media transfer as well as direct effect systems. Direct exposure to pyrophosphate increased nonadherent monocyte survival (by 120% without LPS and 235% with LPS) and MSC viability (LDH) (by 16-19% with and without LPS). Conditioned media from LPS-primed monocytes significantly upregulated osteogenic genes (ALP and RUNX2) and downregulated adipogenic (PPAR-γ) and chondrogenic (SOX9) genes in recipient MSCs. Moreover, the inclusion of PPi (250 μM) resulted in a 1.2- to 2-fold significant downregulation of SOX9 in the recipient MSCs, irrespective of LPS stimulation or culture media type. These results indicate that conditioned media from LPS-stimulated inflammatory monocytes potentiates the early MSCs commitment towards the osteogenic lineage and that direct pyrophosphate exposure to MSCs can promote their viability and reduce their chondrogenic gene expression. These results are the first to show that pyrophosphate can act as a survival factor for both human MSCs and primary monocytes and can influence the early MSC gene expression. Graphical abstract.
