Lysgaardnedergaard2535

03 Barrer, which is 20.00 times higher than that of the EC/IL hybrid matrix membrane. The permeability coefficient of O2 reached 321.01 Barrer, which is 19.21 times higher than that of the EC/IL membrane. When the doping amount of BBPMS is 70-80%, the O2/N2 gas permeation separation of the BBPMS/EC/IL ternary composite membrane is close to the Robertson 2008 curve. It is always known that in the gas separation process the membrane material is the most crucial factor. The success of this experiment points to a new direction for the preparation of new membrane materials.Refractory gold ore is usually affected by the associated carbonaceous matter through the preg-robbing effect, which is eliminated by oxidation roasting, followed by leaching, to achieve a satisfactory gold leaching efficiency. Roasting-leaching experiments, pore structure measurements, scanning electron microscopy (SEM), and X-ray diffraction are used to explore the structural evolution of pores on the surface and its effect on the leaching performance. Pores with optimal sizes were obtained by roasting at 650 °C for 2.0 h with a ventilation of 0.6 m3/h; approximately 92.55% gold could be recovered under these conditions. A porous structure observed by SEM became more compact as the temperature further increased to 850 °C. The formation of CaSiO3 and CaSO4 in pores led to pore shrinkage. The mechanism of oxidation roasting, followed by cyanide leaching, was schematically analyzed and revealed the effects of pore structural evolution and phase transformation on the leaching efficiency.Grignard reactions are an efficient way to form carbon-carbon bonds with widespread applications in large-scale processes. Classically, the electrophiles of choice to form ketones from Grignard reagents are acid chlorides. The reactions are typically catalyzed by additives such as CuCl to increase selectivity and yields. This work was focused on the use of acetic anhydride as an alternative to acetic chloride in the synthesis of 4-fluoro-2-(trifluoromethyl)acetophenone (3), a useful intermediate for the synthesis of active agricultural ingredients. The use of acetic anhydride as an electrophile not only equals but also surpasses acetic chloride in yield and selectivity, while also being more tolerable toward higher reaction temperatures. Furthermore, the reaction was performed in the absence of any additive, making it a highly attractive process for large-scale production. Computational mechanistic studies suggest that this advantageous behavior can be ascribed to the superior complexation of carboxylic acid anhydrides in the transition state.We investigated the energy transfer in the 2 u (1 D 2) ion-pair state of I2 by collision with noble gas atoms, Ar, Kr, and Xe, using an optical-optical double resonance/fluorescence detection technique. By analyzing the temporal profiles of the emission from the laser-excited 2 u (1 D 2) state at various noble gas pressures, the quenching rate constants were determined to be (4.55 ± 0.42) × 10-10, (4.23 ± 0.11) × 10-10, and (6.83 ± 0.16) × 10-10 cm3 molecule-1 s-1 for quenching by Ar, Kr, and Xe, respectively. The 2 g (1 D 2) ion-pair state, lying in the vicinity of the 2 u (1 D 2) state, was identified as a destination state by collision with Ar and Kr. 8-Cyclopentyl-1,3-dimethylxanthine chemical structure Collision with Xe provided a new reactive pathway forming the excimer XeI(B). The rate constants were determined to be = (9.61 ± 0.63) × 10-11 cm3 molecule-1 s-1 and = (4.87 ± 0.34) × 10-11 cm3 molecule-1 s-1 for the formation of the 2 g (1 D 2) state by collision with Ar and Kr, respectively, and = (6.55 ± 0.19) × 10-11 cm3 molecule-1 s-1 for the formation of XeI(B). The collisional cross sections calculated from the quenching rate constants were considerably larger than the molecular size, owing to the harpoon mechanism.Chemical profiling of both fruit and aerial part extracts of Euphorbia abyssinica via ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) showed them to be a rich source of diverse compounds. A total of 39 compounds in both extracts including flavonoids and phenolic compounds were identified as predominant metabolites. The antioxidant activity of both extracts was evaluated using three different in vitro assays (DPPH, ABTS, and FRAP assays). The E. abyssinica fruit extract demonstrated more potent activity compared to the aerial part extract (IC50 of 85.1 ± 1.07 and 562.3 ± 1.01 μg/mL, respectively) in the DPPH assay. Furthermore, using ABTS and FRAP assays, the antioxidant capacities of the fruit extract were 1063.03 ± 37.8 and 1476.5 ± 95.6, respectively, calculated as μM Trolox equivalent/mg extract. One of the existing markers for cancer chemoprevention is the induction of phase II detoxifying enzyme NAD(P)Hquinone oxidoreductase 1 (NQO1), which plays a vital role in cytoprotection against oxidative damage. The extracts were assessed to test their chemopreventive potential via NQO1 enzyme induction. The methanolic extract of fruits demonstrated a concentration-dependent increase in the cancer chemopreventive marker enzyme NQO1 at the protein expression level in a murine hepatoma cell line (Hepa1c1c7). The interaction with Kelch-like ECH-associated protein 1 (KEAP1) is an essential transcription factor that controls the expression of the NQO1 enzyme. The demonstrated induction of NQO1 by the fruit extract is consistent with a molecular docking study of the effect of dereplicated compounds on the KEAP1 target. Among the dereplicated compounds, hesperidin, naringin, and rutin have been established as promising inducer compounds for the chemopreventive marker NQO1. Our results highlight the E. abyssinica fruit extract as a future chemopreventive lead.Bacillus cereus is a pathogenic bacterium, Gram-positive, aerobic, and facultative anaerobic that can produce spores and different toxins. It is involved in serious foodborne illnesses such as the diarrheal and emetic syndromes, depending on the ingested toxin. This work is aimed to study the potency of electroactivated solutions (EAS) of calcium lactate, calcium ascorbate, and their mixture as antibacterial agents against B. cereus ATCC 14579 vegetative cells. The solutions used were electroactivated under electric current intensities of 250, 500, and 750 mA for 30 min. The obtained EAS were tested in direct contact with B. cereus (107 CFU/mL) for different durations ranging from 5 s to 2 min. Moreover, standard lactic and ascorbic acids were tested as controls at equivalent titratable acidity as that of the corresponding electroactivated solutions. The obtained results showed that EAS exhibit high antibacterial efficacy against B. cereus vegetative cells. The EAS obtained after electroactivation of calcium lactate and calcium ascorbate were more efficient than those of their corresponding standard acids (lactic and ascorbic). The observed antibacterial effect of the EAS resulted in a reduction of 7 log CFU/mL after 5 s of direct contact in some specific cases. Scanning (SEM) and transmission (TEM) electron microscopic observations provided conclusive evidence of the antibacterial activity of the used EAS. These results outlined the highly antimicrobial potency of EAS against B. cereus vegetative cells and that they can be considered in an eventual strategy to ensure food safety, surface cleaning, as well as replacement of hazardous disinfecting chemicals.The R132H mutation in the metabolic enzyme isocitrate dehydrogenase 1 (IDH1) is the most important prognostic factor for the survival of glioma patients. Subsequent studies led to the discovery of a panel of enzymes mainly involved in glutamate anaplerosis and aerobic glycolysis that change in abundance as a result of the IDH1 mutation. To further study these changes, appropriate glioma models are required that accurately mimic in vivo metabolism. To investigate how metabolism is affected by in vitro cell culture, we here compared surgically obtained snap-frozen glioma tissues with their corresponding primary glioma cell culture models with a previously developed targeted mass spectrometry proteomic assay. We determined the relative abundance of a panel of metabolic enzymes. Results confirmed increased glutamate use and decreased aerobic glycolysis in resected IDH1 R132H glioma tissue samples. However, these metabolic profiles were not reflected in the paired glioma primary cell cultures. We suggest that culture conditions and tumor microenvironment play a crucial role in maintaining the in vivo metabolic situation in cell culture models. For this reason, new models that more closely resemble the in vivo microenvironment, such as three-dimensional cell co-cultures or organotypic multicellular spheroid models, need to be developed and investigated.In the freeze coring process, the core tube is subjected to cutting heat, frictional heat with the coal wall, and refrigerant action, which causes the temperature of the coal core to be different at different positions and at different times. The equivalent average temperature is proposed to represent the change law of the whole temperature of the coal core and to provide the temperature boundary condition for calculating gas loss. Relying on the self-developed simulation platform for the freezing response characteristics of gas-containing coal, a temperature change simulation test of the freezing core under different external heat conditions was carried out, and the freezing core heat transfer model was constructed with the help of COMSOL to analyze the coal core radial temperature changes during the freeze coring process. Because the drilling sampling time of the freeze coring process is short and there is a thermal isolation device between the drill bit and the core tube, the influence of cutting heat is ignored when the model is established, and only the coal core diameter is studied. The results show that the law of equivalent average temperature of the coal core with time is consistent with the experimental law, which is divided into three stages rapid decline, slow decline, and relative stability. The temperature drop amplitude and rate of the equivalent average temperature of the coal core decrease with increasing external heat temperature. For example, when the external temperature is 60, 70, 80, and 90 °C, the limit temperatures of the equivalent average temperature of the coal core are -36.301, -30.358, -23.956, and -18.899 °C, respectively.Water saturation assessment is recognized as one of the most critical aspects of formation evaluation, reserve estimation, and prediction of the production performance of any hydrocarbon reservoir. Water saturation measurement in a core laboratory is a time-consuming and expensive task. Many scientists have attempted to estimate water saturation accurately using well-logging data, which provides a continuous record without information loss. As a result, numerous models have been developed to relate reservoir characteristics with water saturation. By expanding the use and advancement of soft computing approaches in engineering challenges, petroleum engineers applied them to estimate the petrophysical parameters of the reservoir. In this paper, two techniques are developed to estimate the water saturation in terms of porosity, permeability, and formation resistivity index through the use of 383 data sets obtained from carbonate core samples. These techniques are the nonlinear multiple regression (NLMR) technique and the artificial neural network (ANN) technique.