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There is a need to facilitate access to mental health care and develop more tailored interventions to reduce discontinuity of care.

Inequalities in the provision of care for migrants are observed in the Parisian public psychiatric system, particularly for those experiencing poor social and economic conditions. There is a need to facilitate access to mental health care and develop more tailored interventions to reduce discontinuity of care.Sleep during infancy is important for the well-being of both infant and parent. Therefore, there is large interest in characterizing infant sleep with reliable tools, for example by combining actigraphy with 24-h-diaries. However, it is critical to select the right variables to characterize sleep. In a longitudinal investigation, we collected sleep data of 152 infants at ages 3, 6, and 12 months. Using principal component analysis, we identified five underlying sleep composites from 48 commonly-used sleep variables Sleep Night, Sleep Day, Sleep Activity, Sleep Timing, and Sleep Variability. These composites accurately reflect known sleep dynamics throughout infancy as Sleep Day (representing naps), Sleep Activity (representing sleep efficiency and consolidation), and Sleep Variability (representing day-to-day stability) decrease across infancy, while Sleep Night (representing nighttime sleep) slightly increases, and Sleep Timing becomes earlier as one ages. We uncover interesting dynamics between the sleep composites and demonstrate that infant sleep is not only highly variable between infants but also dynamic within infants across time. Interestingly, Sleep Day is associated with behavioral development and therefore a potential marker for maturation. We recommend either the use of sleep composites or the core representative variables within each sleep composite for more reliable research.Decision-making autonomy may have played a crucial role in protecting, or on the contrary, intensifying the onset of negative psychological outcomes for workers with roles with responsibilities during the lockdown due to the Covid-19 crisis. The present study analyzed the emotional dimension of workaholism in relation to emotional exhaustion, considering decision-making autonomy as a moderator of this relationship, in a sample of 101 managers and freelancers in the middle of the lockdown in Italy (early April 2020). Results showed that the relationship between negative (workaholic) emotions and emotional exhaustion was moderated by decision-making autonomy and this moderation differed for managers and freelancers. In particular, the results showed that in the target of managers high levels of negative emotional experiences related to workaholism and low decision-making autonomy are associated with higher levels emotional exhaustion, while high levels of emotional experiences linked to workaholism and high decision-making autonomy produced significantly lower levels of emotional exhaustion. On the contrary, low levels of job autonomy were associated to higher level of emotional exhaustion when negative (workaholic) emotions were low for the freelancers. Limitations are related to the limited sample and the cross-sectional nature of the study. Practical implications lie in considering decision-making autonomy as a double-edged sword, such that when low it could be a risk for managers and when high it could be a risk for freelancers.Enzyme catalysis is a very active research area in organic chemistry, because biocatalysts are compatible with and can be adjusted to many reaction conditions, as well as substrates. Their integration in multicomponent reactions (MCRs) allows for simple protocols to be implemented in the diversity-oriented synthesis of complex molecules in chemo-, regio-, stereoselective or even specific modes without the need for the protection/deprotection of functional groups. The application of bio-catalysis in MCRs is therefore a welcome and logical development and is emerging as a unique tool in drug development and discovery, as well as in combinatorial chemistry and related areas of research.Soccer is a high-complexity sport in which 22 players interact simultaneously in a common space. The ball-holder interacts with their teammates by passing actions, establishing a unique communication among them in the development of the game in its offensive phase. The main aim of the present study was to analyze the pass action according to the trajectory of the ball receiver and the space for receiving the ball in terms of success at the end of play. Twenty La Liga 2018/2019 matches of two elite teams were analyzed. A system of notational analysis was used to create 11 categories based on context, timing and pass analysis. The data were analyzed using chi-squared analysis. The results showed that the main performance indicators were the efficiency of the pass, the zone of the field, the trajectory of the receiver and the reception space of the ball, which presented a moderate association with the end of play (p less then 0.001). We concluded that receiving the ball on approach and in separation increased the probability of success by 5% and 7%, respectively, and a diagonal run increased the probability by 7%. Moreover, the combined analysis of these variables would improve the team performance.The aim of this article was to analyze the evidence regarding the effectiveness of intervention programs for children with autism based on the participation of their parents. To obtain the data, a systematic search was carried out in four databases (PsycARTICLES (ProQuest), ERIC (ProQuest), PubMed (ProQuest), and Scopus). The retrieved documents were refined under the inclusion/exclusion criteria, and a total of 51 empirical studies were selected. These studies were first classified according to the function of the intervention objective and, later, by the methodology applied (19 studies were based on comprehensive interventions, 11 focused on the nuclear symptoms of autism spectrum disorder (ASD), 12 focused on the promotion of positive parenting, and nine interactions focused on child play). Once all of the documents had been analyzed, the evidence indicated scientific efficacy in most studies, mainly in those based on child development and the application of behavioral analysis principles. Moreover, the positive influence of parent participation in such programs was demonstrated.We aimed to address the impact of OSA and its treatment with continuous positive airway pressure (CPAP) on major adverse cardiovascular and cerebrovascular events (MACCE) in patients with acute coronary syndrome (ACS). In this current analysis of the revascularized ACS subgroup (n = 353) of the Randomized Intervention with CPAP in Coronary Artery Disease and Obstructive Sleep Apnea (RICCADSA) trial (Trial Registry ClinicalTrials.gov; No NCT00519597), participants with non-sleepy OSA (apnea-hypopnea-index [AHI] ≥ 15 events/h on a home sleep apnea testing, and Epworth Sleepiness Scale [ESS] score less then 10; n = 171) were randomized to CPAP (n = 86) or no-CPAP (n = 85). The sleepy OSA patients (AHI ≥ 15 events/h and ESS ≥ 10) who were offered CPAP, and the ones with no-OSA (AHI less then 5 events/h) were included in the observational arm. A post-hoc analysis was done to compare untreated OSA (no-CPAP; n = 78) and nonadherent sleepy/non-sleepy OSA (n = 96) with the reference group without OSA (n = 81). The primary endpoint (the first event of repeat revascularization, myocardial infarction, stroke or cardiovascular mortality) during a median 4.7-year follow-up was evaluated in time-dependent Cox proportional hazards models adjusted for confounding factors. The incidence of MACCE did not differ significantly in intention-to-treat population. On-treatment analysis showed a significant risk reduction in those who used CPAP for ≥4 vs. less then 4 h/day or did not receive treatment (adjusted hazard ratio [HR] 0.17; 95% confidence interval [CI] 0.03-0.81; p = 0.03). Compared with the reference group, nonadherent/untreated OSA was associated with an increased cardiovascular risk (adjusted HR 1.97, 95% CI 1.03-3.77; p = 0.04). We conclude that OSA is an independent risk factor for adverse cardiovascular outcomes in patients with ACS. CPAP treatment may reduce this risk, if the device is used at least 4 h/day.Superconducting links are an innovative solution for bulk power transmission, distinguished by their compact dimensions, high efficiency and small environmental footprint. As with any new technology field, there is a large amount of design possibilities for such links, each of them having a profound impact on the system configuration. For instance, changing the material can imply a change in the working temperature from 20 to 70 K and has consequences on the maximum link length. This article presents the dichotomic decision possibilities for the optimized design of a high-power superconducting link, focusing on some of the key components of the cable system. The complex design optimization process is exemplified using the European project Best Paths, in which the first 3-gigawatt-class superconducting cable system was designed, optimized, manufactured, and successfully tested.Cementitious composites with microencapsulated healing agents are appealing due to the advantages of self-healing. The polymeric shell and polymeric healing agents in microcapsules have been proven effective in self-healing, while these microcapsules decrease the effective elastic properties of cementitious composites before self-healing happens. The reduction of effective elastic properties can be evaluated by micromechanics. The substantial complicacy included in micromechanical models leads to the need of specifying a large number of parameters and inputs. Meanwhile, there are nonlinearities in input-output relationships. Hence, it is a prerequisite to know the sensitivity of the models. A micromechanical model which can evaluate the effective properties of the microcapsule-contained cementitious material is proposed. Subsequently, a quantitative global sensitivity analysis technique, the Extended Fourier Amplitude Sensitivity Test (EFAST), is applied to identify which parameters are required for knowledge improvement to achieve the desired level of confidence in the results. Sensitivity indices for first-order effects are computed. this website Results show the volume fraction of microcapsules is the most important factor which influences the effective properties of self-healing cementitious composites before self-healing. The influence of interfacial properties cannot be neglected. The research sheds new light on the influence of parameters on microcapsule-contained self-healing composites.The use of actinomycetes for improving soil fertility and plant production is an attractive strategy for developing sustainable agricultural systems due to their effectiveness, eco-friendliness, and low production cost. Out of 17 species isolated from the soil rhizosphere of legume crops, 4 bioactive isolates were selected and their impact on 5 legumes soybean, kidney bean, chickpea, lentil, and pea were evaluated. According to the morphological and molecular identification, these isolates belong to the genus Streptomyces. Here, we showed that these isolates increased soil nutrients and organic matter content and improved soil microbial populations. At the plant level, soil enrichment with actinomycetes increased photosynthetic reactions and eventually increased legume yield. Actinomycetes also increased nitrogen availability in soil and legume tissue and seeds, which induced the activity of key nitrogen metabolizing enzymes, e.g., glutamine synthetase, glutamate synthase, and nitrate reductase. In addition to increased nitrogen-containing amino acids levels, we also report high sugar, organic acids, and fatty acids as well as antioxidant phenolics, mineral, and vitamins levels in actinomycete treated legume seeds, which in turn improved their seed quality.