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of cases showing CBCTPAI scores better than 1, compared to 100% cases scoring 1 + D or worse without GTR. Statistically significant differences were found between treatment arms with respect to CBCTPAI score and pocket depth at 12 months.Conclusions GTR may improve radiographically-assessed healing of combined endo-perio lesions. MTA obturation may play a role in the management of combined endo-perio lesions. Study limitations do not allow for more definitive conclusions.Data source and study design Retrospective cohort study using the data obtained from PlusDental - a Berlin-based health-tech companyCohort selection and data analysis Patients who completed clear aligner therapy (CAT) in 2019 were selected for this study. A digital-based app was utilised for analysing compliance among patients who underwent non-extraction orthodontic treatment with clear aligners. The sample included 2,644 adult orthodontic patients, three-fourths of them being women and one-fourth men. The primary outcome involved patient compliance, which was evaluated using a questionnaire in the app, completed by the patient. The questionnaire required patients to enter details about the aligner change date, daily wear time and pressure exerted by each aligner. The effect of variables including age, sex, previous orthodontic treatment and satisfaction with one's smile on compliance, were also analysed. Statistical analysis was performed using two-sided chi-square tests.Results Only 36% of the patient sample were fully compliant and poor compliance was exhibited by 25%. Authors observed that women were less compliant than men and patients with no prior orthodontic treatment were better compliant towards CAT. Also, patients treated with removable appliances exhibited better compliance among those who had a history of previous orthodontic treatment.Conclusions The authors concluded that non-compliant patients can be identified early, using their results as a guideline. This will help in timely intervention of addressing compliance issues during clear aligner orthodontic treatment.Aim This pilot study evaluated a novel method of teaching dental caries removal to overcome the drawbacks in using plastic teeth that neither simulate carious lesions nor emulate the hard tissues of the tooth.Methods This study evaluated the students' perception of a novel method of pre-clinical teaching of caries removal on 3D-printed teeth with a simulated carious lesion. The lesion was simulated by creating an area of low density within the printed tooth. The study also examined the variation in location and extent of cavity preparation by the participants using a heat map analysis. Students who were in their final year of graduation, in the same university of the researchers, prepared cavities on the 3D-printed teeth and answered a questionnaire on their perceived readiness for clinical practice with conventional teaching versus the 3D-printed teeth.Results Among the 14 participants, a majority stated that they had high levels of anxiety when treating their first carious lesion and that the 3D-printed teeth would have better prepared them to treat patients. More than half indicated that the 3D-printed teeth had a better haptic simulation of caries removal and would have reduced their stress/anxiety when treating their first caries patient. There was a wide variation in the perimeter and the surface area of the cavity preparations by the participants.Conclusion Teaching caries removal with 3D-printed teeth that emulate a carious lesion could help students gain confidence and make them feel better prepared to treat patients in clinics.Aim To investigate the success rate of 'bidirectional' splinting - both internal and external - of teeth with longitudinal cracks and reversible pulpitis, as well as to identify any signs or symptoms that could give a prognostic indication of success.Design Cohort study.Cohort selection Thirty-four teeth from 33 patients visiting the Department of Conservative Dentistry at the Yonsei University Dental Hospital, Seoul, South Korea, between June 2016 and November 2017, diagnosed with longitudinal cracked teeth with reversible pulpitis. Teeth with signs of pulp necrosis, irreversible pulpitis or other types of longitudinal cracks were excluded.Data analysis These teeth were treated by a systematic protocol of initial external splinting with a metal band, crack removal and internal splinting with composite resin, placement of a temporary crown, before a final permanent crown. Symptoms and vitality were assessed at every stage and root canal treatment provided where deemed necessary. The teeth were then followed up for up to four years to assess tooth survival and pulp vitality.Results Accounting for five dropouts during the treatment protocol, 29 teeth reached at least a one-year recall. Of these, 21 (72%) had pulp survival, eight (28%) had required root canal treatment - six of those before final crown cementation - and zero teeth required extraction (100% survival rate). Cracked teeth without initial tenderness to percussion showed a 94% pulp survival rate, while those with tenderness had only a 46% pulp survival rate.Conclusions A systematic approach to treating cracked teeth with reversible pulpitis should be utilised to maintain tooth vitality and survival. Using a bidirectional splinting method provides good outcomes for these teeth. Tenderness to percussion is a significant prognostic indicator of pulp vitality and whether root canal treatment should be initiated.Design This study was a single-centre, single-blind, controlled parallel group randomised control trial.Case selection Participants included those referred to The Hague Clinic for Periodontology in the Netherlands. The selection criteria included patients diagnosed with peri-implantitis, defined as marginal bone loss of >2 mm in addition to bleeding or suppuration on probing and a probing depth of >5 mm. The study was carried out over seven years and involved a control group (full mouth non-surgical peri-implantitis treatment) and a test group (non-surgical peri-implantitis treatment combined with systemic antimicrobials). Data analysis Sixty patients were recruited (30 allocated to each group) and 57 completed follow-up and were analysed according to the intention to treat principle. The patients were reviewed monthly and clinical data according to the parameters being measured were recorded. Microbiological analysis was also carried out. The power calculation was based upon the primary outcome measure of intis.Data sources Electronic searches of studies on orthodontic retainers were conducted up to 12 February 2021 in four electronic databases including Scopus, Web of Science, Embase and PubMed. Only studies in English language were included.Study selection Only clinical studies were included. The inclusion and exclusion criteria were reported. The initial search identified 117 results. After removing duplicate studies, studies were evaluated against the inclusion criteria. Finally, 21 papers were included. Selection of the studies was performed independently by two reviewers. The included studies assessed the effects of the type of orthodontic wire or fibre splint, the material used to bond it to the teeth and the procedure for bonding on the failure rate of the fixed orthodontic retainers.Data extraction and synthesis Data extraction was performed independently by two reviewers. They followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines. The following items on type of bond failure that was observed in fixed lingual retainers. The type of wire or splint has no effect on the failure rate. Results showed that retainers bonded to all teeth were more efficient in maintaining alignment when compared to retainers bonded on the teeth on the ends only. Indirect bonding techniques have no advantage over direct bonding techniques except for shorter chair time. Bonding fibre-reinforced composite retainers were more sensitive to operator skills, hence failure rates would be high if an incorrect technique was used when bonding.Conclusions No fixed retainer can guarantee the stability of alignment stability after orthodontic treatment. Retainers that are bonded to all teeth are preferable to those bonded only at the ends of the wire. Wires and fibre splints were similar regarding failure rates and stability of alignment.Design A randomised crossover clinical trial was designed to determine survival and success of four-implant overdentures in the edentulous maxilla, in participants with mandibular two-implant overdentures. Participants received four implants in the maxilla, two anteriorly and two posteriorly, then were randomly allocated into two treatment groups. The prosthetic phase included alternate loading of anterior and posterior implants for three months each, followed by loading of all four implants for another three months. Participants were then followed up in the recall phase for a mean period of 2.2 years.Case selection Four participants were taken from the authors' previous clinical study, meeting the inclusion criteria for a two-implant overdenture in the mandible. Another 21 participants were recruited from study calls after a widening of inclusion criteria. These patients were all pre-treated in accordance with the previous study protocol, so there was standardisation before maxillary implant placement.Data analysis A sample size calculation was performed and a Kaplan-Meier curve was used to demonstrate implant survival over time.Results Twenty-four patients were included in the study. Three implants were lost during the prosthetic phase and two during the recall phase; all were anterior implants. Implant survival after loading was 93.8% after a mean period of 3.1 years. There were 27 maxillary prosthetic complications overall. Denture success was 95.8% after a mean period of 2.2 years.Conclusions Implant survival of four asynchronously loaded implants in implant-supported overdentures in the edentulous maxilla was good and is a recommendable treatment option for patients with two-implant mandibular overdentures. Implant and prosthetic complications are common but mostly straightforward to manage. Two posterior implants are not superior to two anterior implants, but the majority of patients prefer the four-implant maxillary overdenture.Design A randomised controlled trial study comparing patient-reported outcome measures (PROMs) and experiences (PREs) using conventional brain-guided (free-hand), dynamic computer-assisted implant surgery (dCAIS) and static computer-assisted implant surgery (sCAIS) for dental implant placement.Case selection Ninety subjects who met the inclusion criteria (that is, at least 20 years of age interested in dental implant treatment) accepted to participate in the trial and were randomly allocated to three groups between August 2019 and October 2020, according to the dental implant placement protocol, by means of block randomisation. The included subjects were required to undertake several self-administered questionnaires concerning 1) pre-operative expectations (that is, five items evaluating patients' perceptions using a 5-point Likert scale and six items about patients' expectations concerning the planned surgery); 2) post-operative healing complications or events during the immediate post-operative week (that is, pain intensity assessment on a continuous visual analogue scale [VAS] 0-10, oedema or swelling evaluation on four grades ranging from no oedema [Grade 1] to extraoral oedema reaching beyond the surgical zone [Grade 4] and analgesic drugs intake); and 3) post-operative PROMs at a two-week follow-up (six items evaluating the post-operative symptoms experience and eight items measuring overall patient satisfaction using a 5-point Likert scale).

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