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The role of the left and right hemispheres in processing the gender of voices is controversial, some evidence suggesting a bilateral involvement, some others suggesting a right-hemispheric superiority. We investigated this issue in a gender categorization task involving healthy participants and a male split-brain patient female or male natural voices were presented in one ear during the simultaneous presentation of white noise in the other ear (dichotic listening paradigm). Results revealed faster responses by the healthy participants for stimuli presented in the left than in the right ear, although no asymmetries emerged between the two ears in the accuracy of both the patient and the control group. Healthy participants were also more accurate at categorizing female than male voices, and an opposite-gender bias emerged - at least in females - showing faster responses in categorizing voices of the opposite gender. The results support a bilateral hemispheric involvement in voice gender categorization, without asymmetries in the patient, but with a faster categorization when voices are directly presented to the right hemisphere in the healthy sample. Moreover, when the two hemispheres directly interact with one another, a faster categorization of voices of the opposite gender emerges, and it can be an evolutionary grounded bias.In rats, forelimb movements are evoked from two cortical regions, the caudal and rostral forelimb areas (CFA and RFA, respectively). These areas are densely interconnected and RFA induces complex and powerful modulations of CFA outputs. CFA and RFA also have interhemispheric connections and these areas from both hemispheres send projections to common targets along the motor axis, providing multiple potential sites of interactions for movement production. Our objective was to characterize how CFA and RFA in one hemisphere can modulate motor outputs of the opposite hemisphere. To do so, we used paired-pulse protocols with intracortical microstimulation techniques (ICMS), while recording electromyographic (EMG) activity of forelimb muscles in sedated rats. A subthreshold conditioning stimulation was applied in either CFA or RFA in one hemisphere simultaneously or prior to a suprathreshold test stimulation in either CFA or RFA in the opposite hemisphere. Both CFA and RFA tended to facilitate motor outputs with short (0-2.5ms) or long (20-35ms) delays between the conditioning and test stimuli. In contrast, they tended to inhibit motor outputs with intermediate delays, in particular 10ms. When comparing the two areas, we found that facilitatory effects from RFA were more frequent and powerful than the ones from CFA. In contrast, inhibitory effects from CFA on its homolog were more frequent and powerful than the ones from RFA. Our results demonstrate that interhemispheric modulations from CFA and RFA share some similarities, but also have clear differences that could sustain specific functions these cortical areas carry for the generation of forelimb movements.From reaching to walking, real-life experience suggests that people can generalize between motor behaviors. One possible explanation for this generalization is that real-life behaviors often challenge our balance. We propose that the exacerbated body motions associated with balance-challenged, whole-body movements increases the value to the nervous system for using a comprehensive internal model to control the task. Because it is less customized to a specific task, a more comprehensive model is also a more generalizable model. Here we tested the hypothesis that challenging balance during adaptation would increase generalization of a newly learned internal model. We encouraged participants to learn a new internal model using prism lenses that created a new visuomotor mapping. Niraparib Four groups of participants adapted to prisms while performing either a standing-based reaching or precision walking task, with or without a manipulation that challenged balance. To assess generalization after the adaptation phase, participants performed a single trial of each of the other group's tasks without prisms. We found that both the reaching and walking balance-challenged groups showed significantly greater generalization to the equivalent, non-adapted task than the balance-unchallenged groups. Additionally, we found some evidence that all groups generalized across tasks, for example, from walking to reaching, and vice versa, regardless of balance manipulation. Overall, our results demonstrate that challenging balance increases the degree to which a newly learned internal model generalizes to untrained movements.Pneumatic artificial muscles (PAMs) are an extensively investigated type of soft actuator. However, the PAM motions have been limited somewhat to uniaxial contraction and extension, restraining the development of PAMs. Given the current strong interest in soft robotics, PAMs have been gaining renewed attention due to their excellent compliance and ease of fabrication. Herein, under the inspiration of the elephant trunk, a family of bending and helical extensile PAMs (HE-PAMs)/helical contractile PAMs (HC-PAMs) was proposed and analyzed. Through both experiment and analysis, a model of generalized bending behavior of PAMs was built and developed to investigate the properties of axial, bending, and helical PAMs in the same theoretical framework. The topological equivalence and bifurcation were found in the analysis and utilized to explain the behaviors of these different PAMs. Meanwhile, a coupled constant curvature and torsion kinematics model was proposed to depict the motion of PAMs more accurately and conveniently. Moreover, a soft tandem manipulator consisting of bending and helical PAMs was proposed to demonstrate their attractive potential.Self-continuity, or how an individual understands their sense of self as persisting from past to present and present to future, is an important aspect of the self-concept that is linked to mental health outcomes. This self-concept construct may be particularly pertinent for sexual minority populations, as living in a heterosexist environment may prove detrimental for the development of self-continuity. The current study examined self-continuity among sexual minority and heterosexual community college and university students (N = 292). Compared to their heterosexual peers, sexual minority participants reported lower levels of self-continuity. Self-continuity moderated the associations between victimization due to gender nonconformity and victimization due to sexual minority status and depressive symptoms, such that higher levels of self-continuity were protective among individuals who were experiencing higher levels of victimization due to gender nonconformity or sexual minority status. Findings will be discussed in terms of their implications for identity development among emerging adults.

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