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To retrospectively analyze our interventional radiology outpatient clinics (IROC) for referral patterns, impact on interventional practice, and patient satisfaction.

Consultations performed between 2011 and 2019 were extracted. The two consecutive years with the highest number of consultations (n

 = 1426; n

 = 1595) were compared for unattended consultations (i.e., scheduled consultations with patients not showing-up); initial/follow-up consultations; hospital clinician/general practitioner referrals; initial consultations with radiologists not recommending interventions; procedural conversion rate (PCR; i.e., No. initial consultations resulting in interventions over the total number of initial consultations performed for the same clinical indication). A survey was conducted in 159 patients to determine their satisfaction.

Consultations increased from 2011 to 2019 by 130%. In 2018-2019, the number of unattended consultations was stable (7.0% vs 6.6%; P = .68). The referrals were for back pain (42.2%), interventional oncology (40.5%), and arteriovenous malformations (9.0%). For back pain, in 2019, there were fewer consultations with radiologists not recommending interventions and increased PCR compared to 2018 (11.9% vs. 17.7%; 88.1% vs. 82.3%; respectively; P = .01). For interventional oncology, follow-up consultations and general practitioner referrals increased in 2019 compared to 2018 (43.0% vs 35.3%; P = .01; 24.4% vs. Lipopolysaccharides 12.7%; P < .01; respectively). No other changes were noted. Cumulative 2018-2019 PCR was ≥ 85.4%. 99.2% responders highly appreciated their IROC experience. Quality of secretarial and medical services were the main aspects evaluated to rate the experience with IROC.

IROC results in high PCR. Recent changes in referral/impact on IR practice were noted with patients referred for back pain and interventional oncology.

Level 4, Case Series.

Level 4, Case Series.

The tendency of somatic embryogenesis to regenerate plants only from the L1 layer, associated with the spread of chimerism in grapevine, must be carefully considered in the framework of biotechnological improvement programmes. Grapevine is an important fruit crop with a high economic value linked to traditional genotypes that have been multiplied for centuries by vegetative propagation. In this way, somatic variations that can spontaneously occur within the shoot apical meristem are fixed in the whole plant and represent a source of intra-varietal variability. Previously identified inconsistencies in the allelic calls of single nucleotide variants (SNVs) suggested that the Vitis vinifera 'Nebbiolo' CVT185 clone is a potential periclinal chimera. We adopted the somatic embryogenesis technique to separate the two genotypes putatively associated with the L1 and L2 layers of CVT185 into different somaclones. Despite the recalcitrance of 'Nebbiolo' to the embryogenic process, 58 somaclones were regenerated and Surces of variation. The tendency of somatic embryogenesis to regenerate plants only from L1 must be carefully considered in the framework of biotechnological improvement programmes in this species.In photoelectrochemical (PEC) detection, enhancing the PEC signal and depressing the blank signal are conducive to improve the sensitivity. Because the carbon nanotube (CNT) effectively transfers photogenerated electrons from SnSe to the electrode, the composite nanomaterial CNTs/SnSe generates a strong PEC signal. Methionine (Met), AuNPs, and probe DNA are woven together forming a nanoprobe which is used as a quencher to quench the PEC signal of CNTs/SnSe. When the nanoprobe and CNTs/SnSe are modified onto the electrode, there is a low blank signal. In the presence of metastatic breast cancer cells, the cells interact with the aptamer of dsDNA; concomitantly, cDNA is released to trigger catalytic hairpin assembly (CHA). As a result, a new dsDNA which has an overhang is formed. The nanoprobe on the surface of the electrode hybridizes with the newly formed dsDNA. Subsequently, the nanoprobe is released from the surface of the electrode and the quenching effect between the nanoprobe and the CNTs/SnSe disappears. The PEC aptasensor is linear in the concentration range of 300-5,000 cells/mL, and the detection limit is 180 cells/mL under optimized conditions. The relative standard deviation (RSD) is 3.6% at 10,000 cells/mL. This work demonstrates a promising strategy using CNTs/SnSe as the photoactive material and Met-AuNPs as the quencher to establish a PEC aptasensor with a high PEC response and low blank signal. It can be used to detect bioactive substances at ultralow levels prospectively. Graphical abstract.Psychological distress among healthcare providers is concerning during COVID-19 pandemic due to extreme stress at healthcare facilities, including HIV clinics in China. The socioecological model suggests that psychological distress could be influenced by multi-level factors. However, limited COVID-19 research examined the mechanisms of psychological distress among HIV healthcare providers. This study examined organizational and intrapersonal factors contributing to psychological health during COVID-19 pandemic. Data were collected via online anonymous surveys from 1029 HIV healthcare providers in Guangxi, China during April-May 2020. Path analysis was utilized to test a mediation model among COVID-19 stressors, institutional support, resilience, and psychological distress (PHQ-4). Thirty-eight percent of the providers experienced psychological distress (PHQ-4 score > 3). Institutional support and resilience mediated the relationship between COVID-19 stressors and psychological distress. Psychological distress was common among Chinese HIV healthcare providers during COVID-19 pandemic. Psychological health intervention should attend to institutional support and resilience.The original version of this article, published on 18 august 2020 contained a mistake. An author's name was misspelled.The timed up and go (TUG) test measures physical performance and predicts falls in the elderly. In older women, TUG time predicts the risk of major osteoporotic fracture and hip fracture independently of clinical risk factors and bone mineral density, and has a substantial impact on fracture probabilities.

The timed up and go (TUG) test measures physical performance and predicts falls in the elderly. A slow TUG has been associated with an increased fracture risk, but it is unclear whether the association is independent of clinical risk factors and bone mineral density (BMD). The aim of this study was to investigate if TUG time was associated with fracture risk independently of clinical risk factors and BMD and to determine its impact on fracture probabilities in older women.

A standardized questionnaire was used to assess information regarding clinical risk factors in the large population-based SUPERB study of 3028 older women (75-80years). At baseline, the TUG test was performed and BMD measured with DXA.

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