Listrutledge0695

Of the multiple areas of applications of DNA nanotechnology, stimuli-responsive nanodevices have emerged as an elite branch of research owing to the advantages of molecular programmability of DNA structures and stimuli-responsiveness of motifs and DNA itself. These classes of devices present multiples areas to explore for basic and applied science using dynamic DNA nanotechnology. Herein, we take the stake in the recent progress of this fast-growing sub-area of DNA nanotechnology. We discuss different stimuli, motifs, scaffolds, and mechanisms of stimuli-responsive behaviours of DNA nanodevices with appropriate examples. Similarly, we present a multitude of biological applications that have been explored using DNA nanodevices, such as biosensing, in vivo pH-mapping, drug delivery, and therapy. We conclude by discussing the challenges and opportunities as well as future prospects of this emerging research area within DNA nanotechnology.We report a sustainable strategy to cleanly address biomass waste with high-value utilization. Phenol-rich bio-oil is selectively produced by direct pyrolysis of biomass waste corn straw (CS) without use of any catalyst in a microwave device. The effects of temperature and power on the yield and composition of pyrolysis products are investigated in detail. Under microwave irradiation, a very fast pyrolysis rate and bio-oil yield as high as 46.7 wt.% were obtained, which were competitive with most of the previous results. GC-MS analysis showed that temperature and power (heating rate) had great influences on the yield of bio-oil and the selectivity of phenolic compounds. The optimal selectivity of phenols in bio-oil was 49.4 area% by adjusting the operating parameters. Besides, we have made detailed statistics on the change trend of some components and different phenols in bio-oil and given the law and reason of their change with temperature and power. The in situ formed highly active biochar from CS with high content of potassium (1.34 wt.%) is responsible for the improvement of phenol-rich oils. This study offers a sustainable way to fully utilize biomass waste and promote the achievement of carbon neutrality.The processes currently used in the chemical industry for methane conversion into fuels and chemicals operate under extreme conditions like high temperatures and pressures. In this sense, the search for methane conversion under mild conditions remains a great challenge. This review aims to summarize the use semiconductors and metal-semiconductors as heterogeneous photocatalysts for methane conversion under mild conditions into valuable products. First, a brief presentation of photochemical conversion of methane is provided and then the focus of this review on the use of heterogeneous photocatalysts for methane conversion are described. Finally, the main challenges and opportunities are discussed.3D printing is a type of additive manufacturing (AM), a technology that is on the rise and works by building parts in three dimensions by the deposit of raw material layer upon layer. In this review, we explore the use of 3D printers to prototype electrochemical cells and devices for various applications within chemistry. Recent publications reporting the use of Fused Deposition Modelling (fused deposition modeling®) technique will be mostly covered, besides papers about the application of other different types of 3D printing, highlighting the advances in the technology for promising applications in the near future. Different from the previous reviews in the area that focused on 3D printing for electrochemical applications, this review also aims to disseminate the benefits of using 3D printers for research at different levels as well as to guide researchers who want to start using this technology in their research laboratories. Moreover, we show the different designs already explored by different research groups illustrating the myriad of possibilities enabled by 3D printing.Photocatalysts have been paid great attention owing to their excellent performance in the degradation of dangerous organic pollutants. U0126 Herein, a novel longitudinally grown WO3 photocatalyst was prepared by using a hydrothermal process, which had strong ultraviolet, visible light absorption, and weak near-infrared (NIR) absorption. The WO3 photocatalyst exhibited excellent performance in the rapid degradation of methylene blue (MB) in industry. The photothermal effect is mainly responsible for the rapid degradation of MB under NIR laser irradiation. Besides, different morphologies and structures affect the degradation of MB. The longitudinally grown enlarged the contact area between photocatalyst and MB, and expanded the scope of the absorption wavelength of light, enhancing the stability of photocatalytic materials. So this unique transverse longitudinal structure exhibited a potential capability for degrading organic pollutants.The development of large, multifunctional structures from sustainable wood nanomaterials is challenging. The need to improve mechanical performance, reduce moisture sensitivity, and add new functionalities, provides motivation for nanostructural tailoring. Although existing wood composites are commercially successful, materials development has not targeted nano-structural control of the wood cell wall, which could extend the property range. For sustainable development, non-toxic reactants, green chemistry and processing, lowered cumulative energy requirements, and lowered CO2-emissions are important targets. Here, modified wood substrates in the form of veneer are suggested as nanomaterial components for large, load-bearing structures. Examples include polymerization of bio-based monomers inside the cell wall, green chemistry wood modification, and addition of functional inorganic nanoparticles inside the cell wall. The perspective aims to describe bio-based polymers and green processing concepts for this purpose, along with wood nanoscience challenges.Kinase dysregulation is greatly associated with cell proliferation, migration and survival, indicating the importance of kinases as therapeutic targets for anticancer drug development. However, traditional kinase inhibitors binding to catalytic or allosteric sites are associated with significant challenges. The emergence of resistance and targeting difficult-to-degrade and multi-domain proteins are significant limiting factors affecting the efficacy of targeted anticancer drugs. The next-generation treatment approaches seem to have overcome these concerns, and the use of proteolysis targeting chimera (PROTAC) technology is one such method. PROTACs bind to proteins of interest and recruit E3 ligase for degrading the whole target protein via the ubiquitin-proteasome pathway. This review provides a detailed summary of the most recent signs of progress in PROTACs targeting different kinases, primarily focusing on new chemical entities in medicinal chemistry.