Lindgrenmahler8017

58±1.003 after 6 and 12 months, respectively. Also, the results showed a significant difference in PES between the 6-month and 12-month intervals (P less then 0.05). Conclusion. IIR is a viable method that resulted in optimal aesthetic outcomes based on PES in the short term. Considering its confirmation in this study and previous studies, it is recommended that dentists apply this method.Background. This in vitro study aimed to evaluate biofilm accumulation on and deactivation force of orthodontic nickeltitanium (NiTi) archwires before and after exposure to an oral medium. Methods. Four commercial brands of orthodontic NiTi 0.016" archwires were examined before and after exposure to the oral medium for 4 weeks. Six archwire segments, 30 mm in length, from each manufacturer were tested in a device with four selfligating brackets, channel 0.022", adapted to a universal test machine to evaluate the deactivation force between 0.5 and 3 mm of deflection. The presence of biofilm on the archwire surfaces was evaluated by scanning electron microscopy, before and after exposure to the oral medium. The Wilcoxon and kappa tests were applied to the biofilm scores, three-way ANOVA for repeated measures (Bonferroni post-test), and linear regression between biofilm and deactivation force. Results. The exposure to the oral medium promoted moderate to severe presence of debris on the archwire surfaces and caused a reduction in deactivation force for the Ormco and GAC brands, while maintaining them with adequate force levels. The MORELLI and ORTHOMETRIC archwires underwent no significant reduction in deactivation force; moreover, these maintained elevated levels of force after exposure to the oral medium. The Spearman test indicated a low correlation between biofilm accumulation and deflection force for the Morelli (R2=0.132 and P=0.683) and Orthometric (R2=0.308 and P=0.330) brands. On the other hand, the GAC (R=0.767 and P=0.004) and ORMCO (R=0.725 and P=0.008) brands exhibited statistically significant correlation between these variables. Conclusion. Exposure to the oral medium for one month might give rise to significant changes in the dissipation of forces of orthodontic NiTi archwires, resulting from biofilm accumulation.Background. This study aimed to evaluate the effect of different pouring times and spacer thicknesses on the three-dimensional accuracy of casts made of 3D-printed custom trays. Methods. A partial edentulous maxillary model was scanned for fabricating custom acrylic trays. Twenty custom trays were created using a CAD/CAM system and divided into two groups in terms of their spacer thicknesses (2 mm and 4 mm). All the trays were designed with 2-mm thickness, multiple retentive holes measuring 2 mm in diameter, and three interior seating stops (two on the edentulous ridge and one on the incisal edge of the central incisors). Impressions were made using monophasic polyvinyl siloxane and poured in two different times (one hour and 24 hours after removal) with type IV dental stone. All the casts were scanned to measure three distances (inter-buccal cusps, inter-palatal cusps, and inter-fossa distances) between the two first premolars. The data were analyzed with two-way ANOVA and Bonferroni test at a significance level of 0.05. Results. There was no significant difference between the 3D accuracy of casts made using two different spacer thicknesses poured at 1-hour and 24-hour intervals. However, there was a difference between casts made after 1 hour and 24 hours when using custom trays with 2 mm of spacer thickness in terms of inter-buccal distance. Conclusion. There was no significant difference between the accuracy of casts made using custom trays with either 2 or 4 mm of spacer thickness, which were poured 1 hour or 24 hours after tray removal.Background. Periodontitis and rheumatoid arthritis have similar epidemiology and pathophysiology. Thiamet G cell line Understanding the interaction between these two diseases is vital in our settings. We set out to assess the effect of oral hygiene interventions on disease activity of rheumatoid arthritis patients with periodontitis in Kampala, Uganda. Methods. Fifty-eight patients attending an arthritis clinic with rheumatoid arthritis and periodontitis were randomly assigned to either an intervention group or a control group. Patients diagnosed with rheumatoid arthritis at least two years before, who were on the same medication, dose, or formulation for RA treatment during the preceding three months, were included. The patients were >18 years of age, would be available for all the study visits in the next six months, had at least six natural teeth, had periodontal disease classified as Dutch Periodontal Index (DPSI) >3 and provided written informed consent. Those who had a chronic disorder requiring chronic or intermittent use of antibiotics, were pregnant, were lactating, or had intent to become pregnant were excluded. The primary outcome measure was a change in Disease Activity Score of 28 Joints (DAS28 score) in two 3-month follow-up periods after the intervention. The secondary outcome measure was a change in periodontal status. Results. There was a statistically significant improvement in the DAS-28 score in both the intervention and control arms during the follow-up period (P less then 0.01). The participants carrying more than one bacterial species had worse DAS-28 scores. Conclusion. Oral hygiene interventions given to RA patients could drastically improve their RA treatment outcomes, especially in resource-limited settings.Background. Due to the effect of pre-heating on the degree of conversion of composite resins and the possible effect on cytotoxicity, the effect of pre-heating of bulk-fill composite resins was investigated on cytotoxicity in this study. Methods. In this study, three different types of composite resin were used, including Tetric N-Ceram Bulk-Fil, Xtrafil, and Xtrabase. From each composite resin, 10 cylindrical samples (5 mm in diameter and 4 mm in height) were prepared, with five samples preheated to 68°C, and the other five samples polymerized at room temperature (25°C). Twenty-four hours after polymerization, cytotoxicity was assessed by MTT assay on human fibroblasts. Statistical analysis of data was carried out with two-way ANOVA and Sidak Post-Hoc. The significance level of the test was determined at 0.05. Results. There was no statistically significant difference between the mean percentage of cytotoxicity in terms of pre-heating (P>0.05), but the cytotoxicity of the studied composite resins was significantly different (P less then 0.