Lillelundpalmer7307
Upregulation of Mucin 4 in tumour tissue with no expression in normal epithelium was found and loss of Mucin 4 expression with increase in tumour grade was noted.
Upregulation of Mucin 4 in tumour tissue with no expression in normal epithelium was found and loss of Mucin 4 expression with increase in tumour grade was noted.
The objective of the study was to determine the current prevalence of Helicobacter pylori infection among Dyspepsia patients and correlate this with Endoscopic findings.
A retrospective, descriptive facility-based study was conducted from June to December 2017 to estimate the prevalence of Helicobacter pylori among dyspepsia patients from Majmaah, Sudair, Zulfi and Shaqra areas of Riyadh region, Saudi Arabia. Four years data from January 2012 to December 2016 were reviewd by a checklist and analyzed by SPSS.
Out of 1398 dyspepsia patients, 485 (34.7%) were positive and 913 (65.3%) were negative for H-Pylori infection. Majority of patients 1143 (81.7%) had gastritis, out of which, 457 (39.9%) of gastritis patients were H-pylori positive. The frequency of H-pylori infection was significantly higher among patients with gastritis (p < 0.001). There was no statistically significant difference in the frequency of H-pylori infection among patients with erosion, ulcer, polyp and cancer (p > 0.05).
The prevalence of H.Pylori was low as compared to other governorates in the kingdom and regional countries. Gastritis was dominating finding on upper gastrointestinal (GI) endoscopy.
The prevalence of H.Pylori was low as compared to other governorates in the kingdom and regional countries. Gastritis was dominating finding on upper gastrointestinal (GI) endoscopy.
To assess schizophrenia patients' approach toward coping with stress in terms of demographic variables.
The cross-sectional descriptive study was conducted at the State Hospital Community Mental Health Centre, Turkey, from November 1, 2013, to April 30, 2014 and comprised patients diagnosed with schizophrenia. Data was collected using Sociodemographic Information Form and the Coping Assessment Questionnaire Inventory. It was analysed using SPSS 18.
Of the 53 patients, 14(26.4%) were females and 39(73.5%) were males. The overall mean age was 38±10.66 years. Highest mean score was recorded for the emotion-focussed coping subscale which was 63.49±10.64. Female patients used emotional social support, focussing on problems and venting emotions techniques (p<0.05). Patients who did not use alcohol received higher scores from religious coping subscales, while patients who used alcohol scored higher from substance use and dysfunctional coping subscales (p<0.05).
Most schizophrenia patients were found to be using emotion-focussed coping methods.
Most schizophrenia patients were found to be using emotion-focussed coping methods.
To determine the frequency of work-related musculoskeletal disorders and to assess postural ergonomic risk among tailors.
The cross-sectional study was conducted from September 2017 to February 2018 in Rawalpindi and Islamabad, Pakistan and comprised tailors of both genders aged 25-60 years, working for more than 6 months and having small and medium enterprises. To calculate ergonomic risk of work posture, Quick Exposure Check was used and work-related musculoskeletal disorders were determined through body mapping chart. Data was analysed using SPSS 20.
Of the 400 tailors, 382(95.5%) were males. The overall mean age of the sample was 36.9±10.96 years. The mean Quick Exposure Check score was 46.11±14.83. Acceptable work posture was found in 373(93.25%) subjects. The most common work-related acute musculoskeletal symptoms were found in the upper back 320(80%).
Most tailors had acceptable work posture but work-related pain in upper back was common.
Most tailors had acceptable work posture but work-related pain in upper back was common.
To evaluate the efficacy of disease-based standard order sets in reducing time of order entry, order processing and medication dispensation in emergency department of a tertiary care hospital.
The pilot study was conducted as part of a retrospective clinical audit using pre- and post-intervention design comprising data from July to September 2013 of the emergency department of a tertiary care hospital in Karachi. Data collected related to the reduction in medicine order entry, processing and dispensing time of eight common emergency conditions with standard order set. Subsequently, standard medication orders for the selected medical conditions were developed together with physicians of emergency and other specialties. Post-intervention data was collected and the two data sets were compared using SPSS version 23.0.
Mean medication order entry and processing time from the physician end reduced from 67.7±22.7 seconds to 20.5±7.1 seconds. Mean medication order processing and dispensing time at pharmacist end reduced from 70.0±22.4 to 20.6±8.8 seconds. The difference between pre- and post intervention values was significant (p<0.001).
Implementation of disease-based standard order set significantly improved efficiency.
Implementation of disease-based standard order set significantly improved efficiency.
To determine the management of professionalism issues by foreign returned doctors who are practicing clinicians after returning from abroad.
The qualitative study was conducted in tertiary care hospitals of Khyber Pakhtunkhwa province from January to August 2016. Purposive sampling technique was used to include foreign returned doctors who shared how they managed professionalism matters in context of contrasting cultures at home and abroad. The participants were interviewed in-depth and the audio records were transcribed verbatim. The data analysis generated codes that were consolidated under categories and then themes.
Interviews with ten foreign returned doctors led to 20 codes that resulted in eight categories out of which four main themes were developed namely; Foreign Cultural influence that observed how their stay abroad have influenced their practice methods. Experience, showed how personal experiences of the interviewees helped forge their practice rules in Pakistan. Social Contract theme includ foreign returned doctors face substantial challenges with adjustment in Pakistan.
Adolescent pregnancies are known to be associated with adverse outcomes. Our objective was to compare pregnancy outcomes amongst adolescents (young adolescents YA 15-17 years; older adolescents OA 18- 19 years) and young adults (20 to 25 years).
Study was conducted at the Aga Khan University Hospital, Karachi. Ten-year retrospective record review was done through convenience sampling. Data was collected on predesigned proforma. Participants were 396 primiparous adolescents (15-19 years) with singleton low-risk pregnancy. Reference-group included 410 primiparous, low-risk, young adults. Pregnancies complicated with preexisting diabetes mellitus, chronic hypertension, renal disorders or cardiac diseases were excluded. Maternal /neonatal outcomes were compared amongst groups.
Out of 806 charts reviewed, 75 (9.3%) were YA, 321 (39.8%) were OA and 410 (50.9%) were 20-25 years old young adults. Most of the un-booked cases were in young adolescents; 17 (22.7% YA), 41 (12.8% OA) and 33 (8.0% reference -group) (p-value 0.001). This group also booked at a later gestational age; YA (19.6±10.4 weeks), OA (17.2±9.3 weeks) and controls (15.5n±8.8 weeks) (p-value 0.002). Gestational age at delivery was not significantly different among the groups. Adolescents had a decreased likelihood of Caesarian section with youngest group having 29% less chance of Caesarian delivery (OR 95% CI 0.41, 0.2) compared to women of 20-25 years of age. Difference in maternal/neonatal outcomes remained insignificant between groups at univariate and multivariate analysis.
Maternal/neonatal outcomes in adolescents were comparable to young adults. Good antenatal care, evidence-based protocols and strong family backing may reduce risks to mothers/babies in adolescent pregnancies.
Maternal/neonatal outcomes in adolescents were comparable to young adults. Good antenatal care, evidence-based protocols and strong family backing may reduce risks to mothers/babies in adolescent pregnancies.
To observe the efficacy of platelet rich plasma on pain improvement in knee osteoarthritis patients and to explore the impact of various facotrs on pain reduction with such a treatment.
The quasi-experimental study was conducted at the Armed Forces Institute of Rehabilitation Medicine, Rawalpindi, Pakistan, from October 2017 to April 2018 and comprised patients with primary knee osteoarthritis. The sample was sub-grouped into "normal", "overweight" and "obese" on the basis of body mass index. Two age-based sub-groups were also formed at ≤ 60 years and >60 years. Three injections of calcium gluconate activated 2.5ml platelet rich plasma were given in the knees at an interval of two weeks each. The pain score was calculated using the numerical rating scale at the 6th week. Data was analysed using SPSS 20.
Of the 50 patients, 26(52%) were females and 24(48%) were males. The overall mean age was 59.6±9.6 years (range 42-75 years), with 22(44%) aged ≤ 60 years. There were 21(42%) patients who were overweight, 7(14%) had normal weight and 22(44%) were obese. There was significant pain reduction post-treatment compared to the baseline (p<0.001). The reduction in pain was not significantly related to gender, age, knee osteoarthritis grade, or body mass index (p>0.05).
Platelet rich plasma significantly improved pain in knee osteoarthritis patients regradless of all age, gender, grade and body mass index.
Platelet rich plasma significantly improved pain in knee osteoarthritis patients regradless of all age, gender, grade and body mass index.
The study aimed to examine effect of prenatal anxiety and depression on the prediction of postnatal anxiety and depression among pregnant women. In addition, to find out mean differences in prenatal and postnatal anxiety and depression among primary and multigravida pregnant women.
This study was conducted at Sargodha Pakistan, on a total number of 100 pregnant women as participants. The sample size was calculated by using sampling adequacy test which confirmed that the sample of 100 was sufficient to carry out the statistical analysis for the present study. Data was collected by administering Edinburgh Postnatal Depression Scale. SPSS-23 was used for data analysis. Birinapant in vivo The study has been completed in one year, from October, 2017 to November, 2018.
Results indicated prenatal anxiety has significant positive correlation with prenatal depression (p< .001), postnatal anxiety (p< .001) and postnatal depression (p< .001). The prenatal depression has significant positive correlation with postnatal anxiety (p< .001) and postnatal depression (p< .001). Results also indicated that postnatal anxiety has significant positive correlation with postnatal depression (p< .001).
In this study, findings suggested that there is significant relationship between prenatal and postnatal psychiatric symptoms.
In this study, findings suggested that there is significant relationship between prenatal and postnatal psychiatric symptoms.
