Lawhinton6235

mulator than in the field, which are caused by truncating headways in the subject direction in the simulator. The cultural background of participants did not result in any discernible difference in passing behavior. The results would support a more extensive use of driving simulators in future passing behavior studies. Young drivers' reckless driving, especially among males, is a global phenomenon and a major cause of injury and death. The behavior of young people, including their driving norms, is influenced by the dominant social discourse in their age group. Thus, the nature of the interaction between young drivers and their peers may contribute to increased or decreased risk exposure not only for everyone in the car, but also for other road users, and therefore warrants deeper examination. This study aims to shed light on driving with friends as a particular case of driving with peers. It was designed to examine the role of the four dimensions of the Safe Driving Climate among Friends (SDCaF) scale, in predicting young drivers' intention to take risks behind the wheel, beyond the contribution of the Theory of Planned Behavior (TPB). The sample consisted of 166 participants (70 men, 96 women), ranging in age from 17 to 24 years, who completed a set of self-report questionnaires. The findings demonstrate that the SDCaF dimensions, and especially perceived friends' pressure while driving, add to the explained variance in intention to engage in risky driving, beyond the variance explained by gender and the three components of the TPB. In addition to its theoretical expansion of the TPB model to include specific components relating to perceived driving with friends, the study's practical significance lies in directing efforts towards revealing pathways to reduce reckless driving among young people, through engaging their friends in the process. As part of the emerging world of intelligent transportation, there is considerable interest in developing connected vehicles that are more capable of identifying and guiding individual drivers' behavior than collecting mileage as a moving cart. The two goals of this study are (a) to build a conceptual framework for driver assessment and (b) develop recommendation systems to evaluate individual driving performance and guide driver behaviors, thus improving the network traffic conditions and individuals' perceived safety. A safety score is defined relatively by comparing a driver's individual pattern to a standard "safe driver" pattern. To elaborate, the proposed system adopts advanced data mining techniques to extract, identify, characterize, and display driving behavior patterns. The scoring system provides a basis of assessing individual drivers, who are then recommended to mimic a nearby "safe" driver in a connected environment. To evaluate and implement the proposed conceptual framework, an anonymous trajectory dataset collected from Pittsburgh urban area is applied to build the scoring system, which is then integrated within a virtually simulated environment. The results show that the proposed behavior assessment and recommendation system framework improves the overall performance of a connected traffic system beyond those attained through baseline connectivity principles. OBJECTIVE The aim of this study was to clarify the mechanism of GABA (□-amino butyric acid)-signaling in the salivary glands by localization of vesicular inhibitory amino acid transporter, a key molecule in GABA-synthesis. DESIGN Parotid, sublingual and submandibular glands of mice at various postnatal stages were examined in immuno-light and electron microscopy as well as immuno-blotting. RESULTS Expression for vesicular inhibitory amino acid transporter was detected in parotid and sublingual glands of both sexes and female submandibular gland throughout postnatal development, while it was negligible in male submandibular glands at and after puberty. The expression in female submandibular glands attenuated after testosterone injection. The immunoreactivity was localized in striated ductal cells, but not acinar cells, in the salivary glands, and it occurred in association with intracellular and plasma membranes of the cells. It also occurred in myoepithelial and vascular smooth muscle cells. CONCLUSIONS GABA-signaling was suggested to be a significant signaling pathway in salivary ductal cells, which was suppressed in male submandibular glands at and after puberty. The suppression in the submandibular duct was by testosterone. In addition, the participation of vesicular inhibitory amino acid transporter in GABA signaling through plasma membranes of the ductal cells was suggested. The significance of occurrence of the immunoreactivity in myoepithelial and smooth muscle cells remains to be further elucidated in terms of implication in GABA signaling. Biocrusts are common biotic components in dryland ecosystems worldwide, they contain diverse soil organisms and effectively enhance soil stability and perform a series of key ecological functions. However, the geographical pattern of microbial communities in biocrusts is rarely assessed, despite it is closely related to the spatial variation of ecosystem functions in drylands. We assessed soil bacterial communities in biocrusts across four ecosystems (Gobi, desert, desert steppe and grassland) in a precipitation gradient (16-566 mm yr-1) in northern China. Bacterial OTU number and phylogenetic diversity did not linearly increase with decreasing aridity, they were significantly lower in Gobi and similar among desert, desert steppe and grassland. Soil bacterial community composition in Gobi and desert were different than those in desert steppe and grassland, and they were similar between Gobi and desert, this suggests the key role of habitat in structuring soil bacterial communities. The geographic pattern of soil bacterial communities was strongly influenced by both geographic distance and environmental factors. The first explanatory factor for the geographic variation of bacterial community dissimilarity differed among four ecosystems, being aridity in Gobi and desert, precipitation in desert steppe, and soil inorganic nitrogen in grassland. The geographic pattern of the bacterial functional group profile showed a similar pattern with community composition across four ecosystems, and the groups of containing mobile elements and gram negative bacteria were more abundant in drier habitats of Gobi and desert. PD-1/PD-L1 Inhibitor 3 PD-1 inhibitor Our results reveal the non-linear changes in diversity, composition and functional group of soil bacterial communities in biocrusts across the precipitation gradient from hyper-arid to semi-humid regions, and suggest that the geographic distance and habitat-specific environmental factors determine the distribution of soil bacterial communities in different ecosystems.