Laursenewing6514

78% of total energy consumption (including heating and cooling) was saved in the building operation period in Harbin City, China. Hence, AAMs made of waste EPS beads and rGO can realize the structural and functional integrated application in the future.Introduction Community acquired urinary tract infections (CA-UTI) are commonly caused by Escherichia coli and Klebsiella spp which are known extended spectrum beta lactamase (ESBL) producers. Objectives To determine, the prevalence and characteristics of ESBL producing of E. coli and Klebsiella spp in the community, and the association of risk factors with ESBL CA-UTI. Methods Descriptive cross-sectional study with urine cultures performed from clinically suspected CA-UTI patients by CLSI standards. Conventional multiplex PCR was performed for gene analysis. Results Cultures were positive in 178 (38%) patients from 465. Majority were females (103, 58%). Most frequently isolated was E. coli (149, 84%) with 68(46%) ESBL producers followed by 16(9%) Klebsiella pneumoniae with 4 (25%) ESBL producers. Majority of patients with ESBL CA-UTI were >50 yrs (35/72, 49%) and 13 (18%) children 80% ESBL organisms show high sensitivity for aminoglycosides, carbapenems, nitrofurantoin, mecillinam and fosfomycin. Frequently isolated ESBL gene was CTX-M. Haematuria and structural abnormalities of urinary tract were significantly associated with ESBL CA-UTIIntroduction Variations in endometrial carcinoma awareness among postmenopausal women may explain the variations in care seeking pattern for symptoms associated with endometrial carcinoma. Objectives To describe the awareness and care seeking pattern for symptoms associated with endometrial carcinoma among postmenopausal women in the district of Colomb Methods A community based descriptive cross sectional study was conducted among 1168 postmenopausal women in the district of Colombo, using multistage cluster sampling technique. A pre-tested interviewer administered questionnaire was used. Descriptive statistics were used to describe the awareness and care seeking pattern. Results Of the sample, 83.6% (95% CI 81.5-85.7, n=977) had heard about endometrial carcinoma. About 56% of women (n=654) were aware that postmenopausal bleeding was a suggestive symptom of endometrial carcinoma. Only 24.0% (n=280) knew that never conceived was a risk factor, 20.6% and 20.9% knew that physical inactivity and obesity were risk factors respectively and 28.0% knew that hormone replacement therapy was a risk factor, for endometrial carcinoma. Of the women, 26.6% (n=311) had experienced some gynaecological symptoms similar to symptoms of endometrial carcinoma during their postmenopausal period. Majority of them had disclosed to the children (n= 155, 49.8%) about the symptoms, 70.7% (n=220) had sought treatment, and the most common reason for seeking treatment was physical discomfort (n=83, 37.8%). A majority had gone to the government hospital (n=75, 34%) to get treatment. Conclusions Low awareness of common symptoms, riskIntroduction Gamma-glutamyltransferase (GGT) and serum uric acid (UA) are known to be associated with cardiovascular disease in obese children Objectives To determine the association of serum UA and GGT with components of metabolic syndrome (MetS) in a group of obese children and determine the validity of UA and GGT in predicting MetS. Methods Cross sectional analytical study was conducted among 205, 5-15 year old obese children. After a 12- hour overnight fast, blood was drawn for glucose, lipid profile, alanine aminotransferase (ALT), aspartate aminotransferase (AST), insulin, UA and GGT. Oral glucose tolerance test (OGTT) was done with 2 hour plasma glucose. Height, weight, waist circumference, blood pressure and fat mass were measured. USS of abdomen was performed to assess hepatic steatosis. Results Chi square test showed statistically significant associations between GGT and UA with triglyceride, insulin resistance (HOMA-IR), AST, ALT, AST/ALT ratio and fatty liver. Additionally UA showed a significant association with the OGTT. With existing cut offs (GGT >30 U/L and UA >330 μmol/L) the sensitivity and specificity of GGT in predicting MetS was 19% (95% CI, 13.63-24.37) and 88.4% (95% CI, 84.02-92.78) respectively while for UA was 28.6% (95% CI, 22.42-34.78) and 80.2% (95% CI, 74.75-85.65) respectively. A new cut off value of 19.5 U/L (sensitivity 56% and specificity 55%) for GGT and 275.5 μmol/L (sensitivity 61% and specificity 54%) for UA predicted MetS with greater accuracy. selleck kinase inhibitor Conclusion GGT and UA are strongly associated with metabolic derangements and these biomarkers are rather weak in predicting MetS.Tricholoma matsutake is an ectomycorrhizal fungus, related with the host of Pinus densiflora. Most of studies on T. matsutake have focused on mycelial growth, genes and genomics, phylogenetics, symbiosis, and immune activity of this strain. T. matsutake is known for its unique fragrance in Eastern Asia. The most major component of its scent is (R)-(-)-1-octen-3-ol and is biosynthesized from the substrate linoleic acid by the sequential reaction of lipoxygenase and peroxide lyase. Here, we report for the first time the biosynthesis of (R)-(-)- 1-octen-3-ol of T. matsutake using the yeast Saccharomyces cerevisiae as a host. In this study, cDNA genes correlated with these reactions were cloned from T. matsutake, and expression studies of theses genes were carried out in the yeast Saccharomyces cerevisiae. The product of these genes expression study was carried out with Western blotting. The biosynthesis of (R)-(-)- 1-octen-3-ol of T. matsutake in recombinant Saccharomyces cerevisiae was subsequently identified with GC-MS chromatography analysis. The biosynthesis of (R)-(-)-1-octen-3-ol with S. cerevisiae represents a significant step forward.Introduction Visceral adiposity index (VAI) is a mathematical index derived from the body mass index (BMI), waist circumference (WC), serum fasting triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C). It reflects visceral adipocyte dysfunction (VAD) and is associated with cardiometabolic risk. Women with polycystic ovarian syndrome (PCOS) have adipocyte dysfunction, which is associated with metabolic disorders. Hirsutism in PCOS is considered to be due to high insulin levels which enhances androgen activity at the pilosebaceous unit. Objectives To determine the association between VAI, hirsutism and cardiometabolic risk factors in patients with PCOS. Methods A total of 99 patients aged 18-40 years with PCOS diagnosed by the Rotterdam consensus criteria-2003 and a hirsutism score of 8 or more according to the Ferriman-Gallway Score (FGS) were studied. BMI, WC, fasting lipid profile, serum leptin, insulin, sex hormone binding globulin (SHBG), free-androgen index (FAI), fasting blood glucose (FBG) and oral glucose tolerance test (OGTT) were determined.