Kyedstraarup2137

When treating UC patients with immunomodulatory agents, the possibility of MF or other types of lymphoma as rare complications must be considered.

The visceral adiposity index (VAI) is a newly developing indicator about visceral fat function and insulin resistance. This research aims to assess the association between organ damage and VAI in the community-dwelling elderly Chinese population.

In total, 3363 elderly participants were recruited between June 2014 and August 2019. VAI was used to measure visceral adipose accumulation, and organ damage was measured with standardized methods, including arterial stiffness, lower extremity atherosclerosis, carotid hypertrophy, left ventricular hypertrophy, micro-albuminuria, and chronic kidney disease.

According to multivariable linear regression analysis, VAI was related to carotid-femoral pulse wave velocity (cf-PWV; β = 0.047, P = 0.024), urine albumin to creatinine ratio (UACR; β = 3.893, P = 0.008), estimated glomerular filtration rate (eGFR; β =  -0.526, P = 0.003) and log

(ankle-to-brachial index) (ABI; β = -0.003, P = 0.024). Using multivariable stepwise logistic regression model, higher VAI was found to be significantly related to cf-PWV > 10m/s (OR 1.44, [95% CI 1.17-1.78]; P

 < 0.001), and chronic kidney disease (CKD; OR 1.54, [95% CI 1.09-2.20]; P

 = 0.015).

Since higher VAI is related to increased risk of arterial stiffness and CKD, it may serve as a useful index for the assessment of arteriosclerosis and CKD in elderly population.

NSS, NCT02368938.

NSS, NCT02368938.Pharmaceuticals and their degradation products which are present in wastewater and superficial waters are becoming an ecological issue. This research investigated the degradation and mineralization of synthetic solutions of the pharmaceutical compound sildenafil citrate (SC) by single ozonation and ozonation jointed with UV radiation (O3/UV). The effects of initial drug concentration (50-125 mg L-1), inlet ozone concentration (35-125 g Nm-3), and UV radiation on SC degradation and decrease of total organic carbon (TOC) were investigated using response surface methodology based on a central composite experimental design. Through the RSM analysis, it was possible to confirm the removal of SC for the entire experimental range. Major intermediates of SC degradation were identified and a degradation pathway was proposed. The kinetics of SC degradation was modeled as a pseudo-first-order reaction with a rate constant ranging between 0.072 and 1.250 min-1. The SC degradation and TOC removal were strongly enhanced by increasing the concentration of gaseous ozone at the inlet and incorporating UV radiation. The highest TOC removal reached at 60 min was 75%, in the O3/UV system, with initial SC content of 50 mg L-1 and inlet ozone concentration of 125 g Nm-3. The degradation rate of SC was increased 3 to 9 times in the presence of UV radiation. Ozone-based advanced oxidation processes appear as a suitable alternative for treatment of the emerging pollutant SC.Since COVID-19 pandemic, indoor air quality control has become a priority, and the development of air purification devices effective for disinfecting airborne viruses and bacteria is of outmost relevance. In this work, a photocatalytic device for the removal of airborne microorganisms is presented. It is an annular reactor filled with TiO2-coated glass rings and irradiated internally and externally by UV-A lamps. B. subtilis spores and vegetative cells have been employed as model biological pollutants. Three types of assays with aerosolized bacterial suspensions were performed to evaluate distinct purification processes filtration, photocatalytic inactivation in the air phase, and photocatalytic inactivation over the TiO2-coated rings. The radiation distribution inside the reactor was analysed by performing Monte Carlo simulations of photon absorption in the photocatalytic bed. Complete removal of a high load of microorganisms in the air stream could be achieved in 1 h. Nevertheless, inactivation of retained bacteria in the reactor bed required longer irradiation periods after 8 h under internal and external irradiation, the initial concentration of retained spores and vegetative cells was reduced by 68% and 99%, respectively. Efficiency parameters were also calculated to evaluate the influence of the irradiation conditions on the photocatalytic inactivation of bacteria attached at the coated rings.The main objective of this study was to capture farmers' perceptions and adaptations to climate change in agriculture sector. Along with this, it also identified farmers' adaptations to perceived climate change. Binary logit models were applied on data of 386 farmers, collected from three different agro-ecological zones of Punjab, Pakistan, to present a comprehensive analysis of different adaptation strategies missing in the existing literature. The coefficients of a binary logit model only explain the direction of change; therefore, to see the magnitude of change, marginal effects were also estimated. Findings revealed that farmers perceived climate change and opted different adaptation strategies. buy PT-100 Results of binary logit models described age, education, farming experience, landholding, access to climate information, access to credit facilities, and access to extension services as important determinants of adaptation. This research also found lack of access to climate information, lack of irrigation resources, and knowledge about appropriate adaptations as key constraints in adaptation process. This situation can be improved by enhancing institutional support and capacity. It is suggested that improved agricultural education with better access to climate information and extension services affects the farmers' well-being directly and hence is good for the economy of Pakistan.The effectiveness of compost, peat-calcite, and wood ash to remove Ni from a circum-neutral-contaminated mine water was tested in continuous flow experiments. Materials were compared in 4.8-L columns at hydraulic residence times (HRT) of ∼ 16.5 h over the course of 2.5-4 months. During this period, all columns successfully treated over 400 L of synthetic contaminated neutral drainage (4.05 mg/L Ni), mainly through sorption processes. Mid-column results (HRT ∼ 9 h) indicated that wood ash was the most effective material for Ni removal, and chemical extractions revealed that retained Ni was less mobile in this spent material. The pH-increasing properties of wood ash played a major role in this material's performance, but a pH correction would be required in the initial stages of full-scale treatment to maintain the effluent within regulatory limits (6-9.5). Scaled to full-sized, mid-column results indicated that treatment cell sizes, designed for the 1-year treatment of a high discharge (10 m3/h)-contaminated effluent (4.