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Various subdisciplines of ergonomics science have emerged during the past decades as our insight has been broadened of human and performance. The three main branches of ergonomics have evolved over time focusing on the physical, cognitive, and organizational aspects. But the question is, can these disciplines focus and research enough on the ergonomic aspects of cyberspace and Industry 4.0 technologies? Cyber-technologies of the Fourth Industrial revolution are dramatically imposing themselves on our life and work. This has been led to emerging cyber-aspects for human work and life. Hence, many sciences, mainly applied ones, have upgraded to their cyber versions to deal with the emergent issues, usually with a new name, including the cyber prefix. Cyber-medicine, cyber-health, cyber-commerce, and cyberpsychology are some examples. Also, ergonomics requires a similar look. Ergonomic benefits and threats of Industry 4.0 technologies must be considered in an integrated manner. click here This paper addresses this issue. First, the emergence and development of ergonomics and its subdisciplines chronologically is reviewed. Then, Cybergonomics as a new name and concept is proposed and defined as the ergonomics of Industry 4.0 era. Justification for this portmanteau is described, and an outline of the new realm is explained. Finally, a research road map is proposed for this new subdiscipline of ergonomics.

The COVID-19 pandemic and restrictions on travel and quarantine measures made people turn to self-medication (SM) to control the symptoms of their diseases. Different studies were conducted worldwide on different populations, and their results were different. Therefore, this global systematic review and meta-analysis was conducted to estimate the pooled prevalence of self-medication.

In this systematic review and meta-analysis, databases of Scopus, PubMed, Embase, and Web of Science were searched without a time limit. All eligible observational articles that reported self-medication during the COVID-19 pandemic were analyzed. Heterogeneity among the studies was assessed using Cochran's Q test and I

statistics. A random-effects model was used to estimate the pooled prevalence of self-medication. The methodological quality of the articles was evaluated with the Newcastle-Ottawa Scale.

Fifty-six eligible studies were reviewed. The pooled prevalence of self-medication was 48.6% (95% CI 42.8-54.3). The highest and lowest prevalence of self-medication was in Asia (53%; 95% CI 45-61) and Europe (40.8%; 95% CI 35-46.8). Also, the highest and lowest prevalence of self-medication was related to students (54.5; 95% CI 40.8-68.3) and healthcare workers (32.5%; 16-49). The prevalence of self-medication in the general population (48.8%; 40.6-57) and in patients with COVID-19 (41.7%; 25.5-58). The prevalence of self-medication was higher in studies that collected data in 2021 than in 2020 (51.2 vs. 48%). Publication bias was not significant (

= 0.320).

During the COVID-19 pandemic, self-medication was highly prevalent, so nearly half of the people self-medicated. Therefore, it seems necessary to provide public education to control the consequences of self-medication.

During the COVID-19 pandemic, self-medication was highly prevalent, so nearly half of the people self-medicated. Therefore, it seems necessary to provide public education to control the consequences of self-medication.

China's uneven development under the urban-rural dichotomy has led to the discouraging development of children in rural areas. China is a large agricultural country and agricultural disasters are relatively common. Rural children aged 10-15 whose families depend on the agricultural economy may experience far-reaching negative effects from these disasters.

This study explored the effects of agricultural disasters on rural children's development, including cognitive and noncognitive skills, and academic pressure.

Survey data from the China Family Panel Survey and the National Meteorological Administration for 2010-2018 and a fixed-effect panel model with difference-in-differences regressions were used in the study.

The fixed effects model results showed evidence that agricultural disasters have a negative impact on rural children's cognitive and noncognitive skills and a positive impact on academic pressure. The statistically significant coefficients are -0.092, -0.938, and 0.223, respectively. School and family environments also explain children's development. Robustness tests confirmed these results.

Evidence shows that agricultural disasters have a significant negative impact on rural child development. It may be inferred that these will increase the difficulty of narrowing the urban-rural development gap. China is committed to promoting prosperity for all its people. Special attention should be paid to the consequences of disasters at the child level and appropriate measures should be taken to mitigate possible negative impacts.

Evidence shows that agricultural disasters have a significant negative impact on rural child development. It may be inferred that these will increase the difficulty of narrowing the urban-rural development gap. China is committed to promoting prosperity for all its people. Special attention should be paid to the consequences of disasters at the child level and appropriate measures should be taken to mitigate possible negative impacts.

Increasing the availability of healthy foods within food retail outlets can improve consumers' food environments. Such actions or inactions by food retailers may affect people's food purchasing and consumption behavior. This study explored Accra-based food retailers' perceptions and appreciation of "healthiness of food" as a concept. It also documented measures that food retailers adopt to encourage healthy food choices.

In-person semi-structured interviews were conducted with owners and managers of Accra-based supermarkets (

= 7) and corner stores (

= 13) in March 2021. The interviews were recorded, transcribed, coded, and analyzed thematically.

The retailers' understanding of healthy food, or lack thereof, is exemplified by such expressions as "health, absence of disease, longevity, balanced diet, diversity, sanitation, and certification." A handful of retailers described what they sell as "products that meet consumer needs," "harmless," or "generally good." Very few retailers described the food tng retailers' food and nutrition literacy may improve the availability of healthier options in food retail outlets in Accra.

The purpose of this study was to estimate the cost-effectiveness of sugemalimab plus chemotherapy (SC) vs. placebo plus chemotherapy (PC), as the first-line treatment for patients with non-small cell lung cancer (NSCLC) in China.

A three-state Markov model with a cycle of 3 weeks was built to assess the incremental cost-effectiveness ratio (ICER) of SC vs. PC as first-line treatment for patients with NSCLC over a 10-year horizon from Chinese health care perspective. Time-dependency transition probability and safety data were derived from a multicenter, randomized, double-blind, phase 3 clinical trial performed in China (GEMSTONE-302). Primary model outcomes included the costs in US dollars and health outcomes in quality-adjusted life-years (QALYs) and the ICER under a willingness-to-pay (WTP) threshold of $37,663/QALYs. Deterministic, scenario and probabilistic sensitivity analysis were employed to investigate the robustness of model outcomes.

In base-case analysis, compared with PC, first-line SC for intention-to-treat (ITT) population gained an additional 0.57 QALYs with an incremental cost of $62,404.15, resulting in an ICER of $109,480.97/QALYs gained. When a patient assistance program (PAP) was available, the ICER decreased to $52,327.02/QALYs. In subgroup analysis, the ICER values were above the WTP threshold with or without PAP. Sensitivity analysis results suggested that the model outcomes were reliable.

From the perspective of Chinese healthcare system, the SC was not cost-effective in comparison to PC as first-line treatment for NSCLC, regardless of PD-L1 tumor expression level and pathological subtype.

From the perspective of Chinese healthcare system, the SC was not cost-effective in comparison to PC as first-line treatment for NSCLC, regardless of PD-L1 tumor expression level and pathological subtype.Surveillance of Adverse Events Following Vaccination in the Community (SAEFVIC), Victoria's vaccine safety service for reporting adverse events following immunisation (AEFI), has provided integrated spontaneous surveillance and clinical services for individuals affected by AEFI since 2007. We describe SAEFVIC's response to the COVID-19 vaccine program, and reflect on lessons learned for vaccine safety. The massive scale of the Australian COVID-19 vaccine program required rapid adaptations across all aspects of SAEFVIC's vaccine safety services. Collection of AEFI reports was streamlined and expanded, incorporating both spontaneous and active surveillance data. Dramatically increased report volumes were managed with additional staffing, and innovations to automate, filter, and triage reports for priority follow up. There were two major adverse events of special interest (AESI) thrombosis with thrombocytopaenia syndrome and myocarditis, with multiple other AESI also investigated. Rapid escalation mechanisms to respond to AESI were established, along with AESI-specific databases for enhanced monitoring. Vaccine education and training resources were developed and public-facing vaccine safety reports updated weekly. Frequent communication with local and national government and regulatory bodies, and consultation with specialist groups was essential. The COVID-19 vaccine program has highlighted the importance of vaccine safety in supporting public confidence in vaccines and informing evidence-based immunisation policy. Supporting the COVID-19 vaccine program has required flexibility in adapting to policy changes and evolving vaccine safety signals, careful triage and prioritisation, informatics innovation, and enhanced engagement with the public regarding vaccine safety. Long-term investment to continue strengthening vaccine safety systems, building on lessons learned, will be essential for the ongoing success of Australian vaccination programs.Electronic Health Records (EHR) are critical tools for advancing digital health worldwide. In Brazil, EHR development must follow specific standards, laws, and guidelines that contribute to implementing beneficial resources for population health monitoring. This paper presents an audit of the main approaches used for EHR development in Brazil, thus highlighting prospects, challenges, and existing gaps in the field. We applied a systematic review protocol to search for articles published from 2011 to 2021 in seven databases (Science Direct, Web of Science, PubMed, Springer, IEEE Xplore, ACM Digital Library, and SciELO). Subsequently, we analyzed 14 articles that met the inclusion and quality criteria and answered our research questions. According to this analysis, 78.58% (11) of the articles state that interoperability between systems is essential for improving patient care. Moreover, many resources are being designed and deployed to achieve this communication between EHRs and other healthcare systems in the Brazilian landscape.