Knudsenzhu7759

Background Sustainable Development Goal 3.7 aims to ensure universal access to sexual and reproductive health services. One suggested benchmark is to have at least 75% of the demand for contraception satisfied with modern methods (DS) in all countries by 2030. The translation of DS-based targets into targets for the modern contraceptive prevalence rate (mCPR) is needed to make targets actionable. Methods We propose the Accelerated Transition (AT) method for determining the mCPR needed to reach demand-satisfied targets by 2030. The starting point for this method is the projection of DS under "business as usual" using the one-country implementation of the Family Planning Estimation Model (FPEMcountry). For countries in which the DS target is projected to be later than 2030, the AT method assumes that meeting the DS target by 2030 requires an acceleration of the contraceptive use transition such that the DS target, and its associated mCPR, will be reached in 2030 as opposed to the later year. The DS-target-associated mCPR becomes the mCPR target for the year 2030. Results We apply the AT method to assess progress needed for attaining the 75% DS target for married or in-union women in the world's poorest countries. For 50 out of 68 countries, we estimate that accelerations are needed, with required mCPR increases ranging from 4.3 to 50.8 percentage points. Conclusions The AT method quantifies the acceleration needed - as compared to business as usual projections - for a country to meet a family planning target. The method can be used to determine the mCPR needed to reach demand-satisfied targets.Background Preterm birth, defined as infants born before 37 weeks of gestation, is the largest contributor to child mortality. Despite new evidence highlighting the global burden of prematurity, policymakers have failed to adequately prioritize preterm birth despite the magnitude of its health impacts. Given current levels of political attention and investment, it is unlikely that the global community will be adequately mobilized to meet the 2012 Born Too Soon report goal of reducing the preterm birth rate by 50% by 2025. Methods This study adapts the Shiffman and Smith framework for political priority to examine four components contributing to policy action in global health actor power, ideas, political context, and issue characteristics. We conducted key informant interviews with 18 experts in prematurity and reproductive, maternal, newborn, and child health (RMNCH) and reviewed key literature on preterm birth. We aimed to identify the factors that shape the global political priority of preterm birth and too prematurity within the larger RMNCH agendas.Background Neurogenic lower urinary tract dysfunction (NLUTD) is common among people with multiple sclerosis (MS) with a pooled prevalence of 68.41% using self-report measures and 63.95% using urodynamic studies. Transcutaneous tibial nerve stimulation (TTNS) is a non-invasive option to manage bladder storage symptoms; however, the potential efficacy of TTNS among people with MS is based on a small number of studies with the absence of high-quality evidence relating to efficacy, and lack of clarity of the optimal electrical stimulation parameters and frequency, duration and number of treatment sessions. This study aims to assess whether TTNS is feasible and acceptable as a treatment for bladder storage symptoms in people with MS. Methods We will use a single-arm experimental study to explore the feasibility and acceptability of TTNS in the treatment of bladder storage symptoms in MS. The CONSORT extension for pilot and feasibility studies will be followed to standardise the conduct and reporting of the study. The recruitment plan is twofold 1) Open recruitment for people with MS through MS Ireland's communication channels; 2) recruitment from a convenience sample of people with MS who have previously participated in a qualitative interview study of urinary symptoms. mTOR inhibitor We will assess recruitment/retention rates, the urinary symptoms changes and the effect on quality of life pre and post intervention using ICIQ-OAB, 3-day bladder diary, King's Health Questionnaire and collect self-reported data on adherence and adverse events. Acceptability of using TTNS will be evaluated at the end of intervention. This study has been reviewed and approved by the Education and Health Science's Faculty Research Ethics Committee, University of Limerick [2020_06_07_EHS]. Conclusion It is anticipated that assessing the feasibility and acceptability of TTNS for storage bladder symptoms in MS will inform the development of a definitive randomised trial. Trial registration ClinicalTrials.gov NCT04528784 27/08/2020.Visual information and prior knowledge represent two different sources of predictability for tasks which each have been reported to have a beneficial effect on dual-task performance. What if the two were combined? Adding multiple sources of predictability might, on the one hand, lead to additive, beneficial effects on dual-tasking. On the other hand, it is conceivable that multiple sources of predictability do not increase dual-task performance further, as they complicate performance due to having to process information from multiple sources. In this study, we combined two sources of predictability, predictive visual information and prior knowledge (implicit learning and explicit learning) in a dual-task setup. 22 participants performed a continuous tracking task together with an auditory reaction time task over three days. The middle segment of the tracking task was repeating to promote motor learning, but only half of the participants was informed about this. After the practice blocks (day 3), we provided participants with predictive visual information about the tracking path to test whether visual information would add to beneficial effects of prior knowledge (additive effects of predictability). Results show that both predictive visual information and prior knowledge improved dual-task performance, presented simultaneously or in absence of each other. These results show that processing of information relevant for enhancement of task performance is unhindered by dual-task demands.