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The simulation lasts for 10 gait cycles of 1.4 s each and has an output SNR of 15 dB. Two conditions were simulated one in which the profile of joint impedance is periodic, and one in which the amplitude and the shape of the profile slightly vary over the periods. A Monte Carlo analysis is performed and, for both conditions, the proposed method can reconstruct the noiseless simulation output signal and the profiles of the time-varying joint impedance parameters with high accuracy (mean VAF ~ 99.9% and mean normalized RMSE of the parameters 1.33-4.06%).The proposed KBR method with a locally periodic kernel allows for the identification of periodic time-varying joint impedance with cycle-to-cycle variability.Ankle foot orthosis (AFO) stiffness affects ankle range of motion but can also provide energy storage and return to improve mobility. To perform multiple activities during the day, a person may want to change their AFO stiffness to meet their activity's demand. Carrying multiple AFOs and changing AFOs is inconvenient and could discourage users from engaging in multiple activities. This project will develop a new quick-release mechanism (QRM) that allows users to easily change posterior strut elements to change AFO stiffness. The QRM attaches to the AFO and requires no tools to operate. The proposed QRM includes a quick-release key, weight-bearing pin, receptacle anchor, and immobilization pin. A prototype was modelled with SolidWorks and simulated with SolidWorks Simulation. The QRM was designed to have no mechanical failure during intense activities such as downhill walking and jogging. Unlike a solid screw connection, the QRM needed an additional part to eliminate unsecured motion related to clearance between the quick release key and receptacle anchor. Mechanical test results and measurement data proved no deformation on each part after mechanical testing.Clinical Relevance- The quick release AFO has the potential to improve user's activities range by tuning from stiffness free mode to high stiffness mode.Biomechanical movement data are highly correlated multivariate time-series for which a variety of machine learning and deep neural network classification techniques are possible. For image classification, convolutional neural networks have reshaped the field, but have been challenging to apply to 3D movement data with its intrinsic multidimensional nonlinear correlations. Deep neural networks afford the opportunity to reduce feature engineering effort, remove model-based approximations that can introduce systematic errors, and reduce the manual data processing burden which is often a bottleneck in biomechanical data acquisition. What classification techniques are most appropriate for biomechanical movement data? Baseline performance for 3D joint centre trajectory classification using a number of traditional machine learning techniques are presented. Our framework and dataset support a robust comparison between classifier architectures over 416 athletes (professional, college, and amateur) from five primary and six non-primary sports performing thirteen non-sport-specific movements. buy GSK2578215A A variety of deep neural networks specifically intended for time-series data are currently being evaluated.In this work, we quantify the neck's involvement in stabilizing the head during falls in older adults to avoid head impacts. We tracked kinematics of 12 real-world backward falls in long-term care captured on video, where head impact was avoided. We estimated dynamic spring-dashpot parameters of the neck and hip representing active muscle activity and passive tissue structures. Neck stiffness, damping, and target posture averaged 24.00±6.17Nm/rad, 0.38±0.16Nms/rad, and 76.2±14.7° flexion respectively. The stiffness and target posture suggest that residents actively contracted their neck muscles to maintain the head upright. Our results shed light on the importance of neck strength for avoiding head impact during a fall.Clinical Relevance-Falls account for 80% of traumatic brain injuries in adults 65+ years. While upper limb bracing can reduce the risk of head impacts during a fall in young adults, this protective response is less effective in older adults living in longterm care. Understanding how the neck and torso musculature are used to avoid head impact can guide the design of therapeutic exercise programs and assistive or protective devices.Appropriate regulation of joint impedance is required to successfully navigate our environment. Joint impedance is strongly dependent upon the mechanical properties of the muscles and tendons spanning it. While the impedance of the joint has been well characterized, methods to determine the individual contribution from the muscles and tendons are limited. This is a crucial gap as muscle and tendon impedance can be selectively altered by aging, pathology, or injury. Therefore, we developed an innovative in vivo method that allows for the simultaneous quantification of joint, muscle, and tendon impedance. Stochastic perturbations of ankle angle were applied while a B-mode ultrasound was used to image the displacement of the medial gastrocnemius muscle-tendon junction. Non-parametric system identification was used to quantify ankle impedance and the frequency response function between ankle rotations and muscle-tendon junction displacements. The latter represents, when scaled by Achilles tendon moment arm, the ratio between the net musculotendon impedance and the impedance of the muscle, a relationship we refer to as the impedance ratio. Muscle and tendon impedance can be calculated from these experimental estimates. The ability to simultaneously quantify joint, muscle, and tendon impedance will provide a clearer understanding their respective roles in our ability to navigate our environment, and how changes in those roles may contribute to functional impairments.Knee orthoses are designed to reestablish the normal kinematics of the knee joint. However, the data on the effectiveness of them on modifying the internal joint kinematics are scarce. The aim of this study was to develop a method to allow accurate comparison of the knee contact kinematics in osteoarthritic (OA) subjects with and without wearing a valgus knee orthosis using imaging techniques. Biplane x-ray images of a subject (68 yrs., female, 1.70 m, 89 kg, left knee) was recorded during a weight-bearing squat at five positions. The same squat trial was repeated while wearing the orthosis. The 3D models of the knee were reconstructed from the biplane x-rays and the joint kinematics as well as the tibiofemoral contact point locations and bone-to-bone distance were compared at each posture. This could be seen as a proof of concept for the use of contact point locations as a parameter for evaluating the effectiveness of knee orthoses.Clinical Relevance- Joint kinematics derived from the skin markers suffer from low accuracy.

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