Katzpoole7213

BACKGROUND/AIM A new bioceramic material iRoot BP Plus has been introduced and reported to have good biocompatibility, sealing ability and antibacterial activity. It has also been reported to be successfully used for procedures such as pulpotomy, pulp floor perforation repair and so on. However, there are only a few reports on the use of iRoot BP Plus in the management of traumatised teeth with an exposed pulp. The aim of this study was to investigate the clinical and radiographic outcomes of partial pulpotomy with iRoot BP Plus in immature permanent teeth with complicated crown fracture or complicated crown-root fracture. Sunitinib cell line MATERIAL AND METHODS The study was prospectively designed and 110 immature permanent teeth with complicated crown fracture or complicated crown-root fracture were randomly allocated into two groups (n = 55). All teeth were clinically and radiographically assessed at 1, 3, 6, 12, 18 and 24 months after partial pulpotomy with iRoot BP Plus (experimental group, n=50) or calcium hydroxide (control group,n=49) as the pulp capping agent. Eleven cases were lost during follow-up, and 99 teeth were finally analysed. RESULTS There were no intergroup differences in the survival rate, survival time, root length and dentin wall thickness. The calcific bridge was significantly thinner in the iRoot BP Plus group than in the calcium hydroxide group (0.97±0.13mm vs. 1.36±0.12mm; F=5.128, P=0.029). CONCLUSIONS iRoot BP Plus may be an effective capping material for partial pulpotomy. This article is protected by copyright. All rights reserved.BACKGROUND Coeliac disease (CD) is a chronic, autoimmune disease that prevents individuals from processing gluten, leading to adverse health effects. People with CD should adhere to a gluten-free diet (GFD); however, adherence rates are well below optimal in adults with CD, ranging between 42% and 91%. To date, limited evidence is available on the nature and magnitude of factors that affect adherence to GFD. The present study aimed to develop a systematic review that critically appraises and synthesises evidence on facilitators and barriers that affect adherence to GFD among adults with CD. METHODS Four databases were searched (Ovid Medline, CINAHL, PsychInfo and Embase) using variant keywords to identify empirical studies meeting the inclusion/exclusion criteria. A coding scheme was developed to extract relevant information from each article. RESULTS Forty articles were included. Grounded in the bioecological theory of development, we synthesised the facilitators and barriers in the literature into a social ecological model with multiple levels system, community, organisational, interpersonal and individual. The studies varied by design and level of evidence; only one randomised trial was identified. The most significant facilitators include (% of studies) increased education (22.5%); increased knowledge of a GFD (20%); increased intention/self-regulatory efficacy (17.5%); and coeliac association membership (12.5%). The most significant barriers include lower knowledge of CD (35%); restaurant/supermarket shopping (30%); poor patient education from practitioner (17.5%); and low intention/motivation to adhere to a GFD (17.5%). CONCLUSIONS Improving knowledge of a GFD, becoming a member of a coeliac association, and improving practitioners' abilities to educate patients on CD will create opportunities for improved adherence to GFD among adults with CD. © 2020 The British Dietetic Association Ltd.AIM The infection of Helicobacter pylori (H. pylori) has a close association with gastric ulcers and gastric adenocarcinoma. This study was designed to assess the efficacy and safety of quadruple regimen with amoxicillin plus berberine vs tetracycline plus furazolidone in H. pylori rescue treatment. METHODS We conducted a randomized, open-label, multicenter, noninferiority trial. Subjects with previous treatment failures recruited from 5 centers were randomized (11) to accept regimen with esomeprazole and bismuth plus either berberine and amoxicillin (BA group) or tetracycline and furazolidone (TF group) for 14 days. The H. pylori infection status was confirmed at 4-8 weeks after treatment. The eradication rate was the study's primary outcome and trial's secondary outcomes included the rates of symptom improvement, compliance and adverse events. This study was registered at ClinicalTrials.gov (NCT03609892). RESULTS 658 subjects were consecutively enrolled in total. ITT analysis demonstrated that the two therapies achieved a similar eradication rate (76.3% vs 77.5%; P = 0.781). PP analysis reached a similar result (81.5% vs 85%; P = 0.278). Difference in the eradication rate achieved by BA quadruple regimen was greater than the preestablished margin of noninferiority, at -10% (the lower bounds of the 95% CI were - 7.66% and - 9.43%, respectively). The rate of adverse events was lower for BA than TF therapy (18.5% vs 26.1%, P = 0.024). The rates of compliance and symptom improvement were similar for the two therapies. CONCLUSION The efficacies of the two regimens in rescue treatment were both not satisfactory, and two groups showed no significant difference. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.OBJECTIVES The aim of this anatomical study is to make quantitative comparison among three endoscopic approaches, encompassing contralateral endonasal transseptal transmaxillary transpterygoid approach (contralateral EEA), endoscopic sublabial transmaxillary transalisphenoid (Caldwell-Luc) approach, and endoscopic transorbital transmaxillary approach through inferior orbital fissure (ETOA), to the anterolateral skull base for assisting preoperative planning. DESIGN & PARTICIPANTS Anatomical dissections were performed in four adult cadaveric heads bilaterally using three endoscopic transmaxillary approaches described above. SETTING Skull Base Laboratory at the National Defense Medical Center. MAIN OUTCOME MEASURES The area of exposure, angles of attack, and depth of surgical corridor of each approach were measured and obtained for statistical comparison. RESULTS The ETOA had significantly larger exposure over middle cranial fossa (731.40 ± 80.08 mm2 ) than contralateral EEA (266.60 ± 46.74 mm2 ) and Caldwell-Luc approach (468.