Johnsblalock6954

Mit einer temporären Gastamponade kann das MH verschlossen werden. ERGEBNISSE Mit einem standardisierten Vorgehen kann die Operation sicher und ohne Komplikationen durchgeführt werden. Maßnahmen wie Sorgfalt bei den luftfreien SR-Flüssigkeitsgaben oder maschinelle Assistenz wurden zusätzlich aufgenommen. In einer Pilotstudie führten erfahrene VR-Chirurgen die SR-Flüssigkeitsapplikation sicher und ohne Komplikationen durch. Der präoperative Durchmesser betrug 1150 µm (651 – 2350 µm). Fingolimod chemical structure Die sekundäre Verschlussrate für unsere PMH betrug 80,9%. SCHLUSSFOLGERUNG SR-Adhärenzen scheinen bei persistierenden Makulaforamen eine bisher unbeachtete Komponente zu haben. Eine SR-Flüssigkeitsapplikation lässt sich sicher, schnell und mit minimalem Materialaufwand durchführen. Die initialen Ergebnisse zeigen eine hohe sekundäre Verschlussrate.in English, German EINLEITUNG Deep Learning erfährt in den zurückliegenden Jahren eine immer größer werdende Aufmerksamkeit und wird für zahlreiche Fragestellungen genutzt. Da Bildanalyse eine der Stärken von Deep Learning ist, liegt der Schluss nahe, auch pathologische Fragestellungen hiermit zu bearbeiten. Ziel dieser Arbeit ist es, aus der allgemeinen Pathologie mögliche Deep-Learning-Ansätze zu identifizieren, die in der Ophthalmopathologie genutzt werden könnten. Zudem soll anhand der Daten eines Jahres der Anteil der potenziell interessanten Präparate für Deep Learning sowie der notwendige Aufwand abgeschätzt werden. METHODEN Es erfolgte zunächst eine Literaturrecherche nach Deep-Learning-Modellen und deren Einsatzmöglichkeiten im Bereich der Pathologie. Um den potenziellen Nutzen abzuschätzen, wurde in einem 2. Schritt für die identifizierten Modelle die Anzahl an geeigneten Präparaten im Jahr 2019 ermittelt und in Relation zu der resultierenden Datenmenge und der Scan-Zeit gesetzt, um die Machbarkeit was technisch machbar erscheint. Zukünftige Studien sollten die konkrete praktische Umsetzung bisheriger Deep-Learning-Möglichkeiten für die Ophthalmopathologie zum Thema haben.in English, German, BACKGROUND The extensive use of antibiotics is reflected by an increasing prevalence of infections with multidrug-resistant bacteria, including third-generation cephalosporin-resistant bacteria (3GCRB). For neonatal intensive care units screening and enhanced barrier precautions are recommended to control the spread of multidrug-resistant Gram-negative bacteria, while evidence for efficacy of barrier precautions remains scarce in a non-outbreak setting. OBJECTIVE To determine the impact of a screening program for maternal 3GCRB colonization and the effects of contact precautions and cohort nursing, concerning the risk of neonatal late-onset sepsis (LOS) and antibiotic use rates (AURs). STUDY DESIGN In a retrospective matched-pair cohort study, data of neonates exposed to maternal 3GCRB colonization were compared with findings in non-exposed neonates. RESULTS Of 3,144 neonates admitted, 184 neonates born to 3GCRB-positive mothers were eligible. Among them, 37 (20%) became 3GCRB positive during hospital stay. 3GCRB-exposed infants had a lower rate of LOS (6.5 vs. 14.1%, p=0.03) and lower AURs in that time period compared to controls (mean 0.009 vs. 0.025, p=0.006). When started within the first 72h after birth, days of therapy with meropenem were significantly lower in non-exposed vs. 3GCRB-exposed infants (mean 0.13 vs. 0.42; p=0.002). No invasive infections with 3GCRB occurred. CONCLUSIONS Neonates of 3GCRB-positive mothers do not have an increased a priori risk for invasive 3GCRB infection and may benefit from enhanced contact precautions measures.BACKGROUND  Reconstruction in tongue cancer to restore the shape and function of the tongue without airway obstruction in the narrow oral cavity is challenging for reconstructive surgeons. Herein, the authors retrospectively analyzed flaps to reveal the factors that affect the functional outcome of tongue reconstruction. METHODS  Herein, we retrospectively reviewed 30 patients (men, 16; women, 14; mean age, 50.3 years) who underwent the hemi-tongue reconstruction followed by speech therapy between 2009 and 2017. Data about postoperative chemotherapy and radiotherapy were collected. The dimensions (width and length) of the flaps were measured. Speech outcomes were assessed under the conditions of varying distances of the tongue tip from lower incisors when it was protruded, retracted, and elevated. Lateralization was evaluated based on the count of teeth reached by the tip of the tongue from the midline. RESULTS  Preoperative chemotherapy and radiotherapy significantly influenced tongue retraction, tongue articulation, and intelligibility (p = 0.006, 0.002, 0.048, respectively). Postoperative chemotherapy did not statistically significantly influence any outcome measure. Contralateralization of the tongue was significantly decreased in the postoperative radiotherapy group (p = 0.029). The length of the flap showed highly negative correlation with articulation and intelligibility (p = 0.009, p less then 0.001, respectively). The width of the flap was not correlated with the outcomes. CONCLUSION  We proved that unlike chemotherapy, postoperative radiotherapy influences the functional outcome of tongue reconstruction. The dimensions, particularly the length of the flap, were also important for restoring the reconstructed tongue function. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.BACKGROUND  Pain management approaches in autologous breast reconstruction have become a topic of great interest in the era of enhanced recovery after surgery protocols, as well as the opioid epidemic. The management of postoperative pain is of critical importance for women undergoing breast reconstruction; however, these protocols have yet to be synthesized and compared in the primary literature. Herein, we present a systematic review of approaches to provide optimal pain control while minimizing narcotic use and its associated potential negative sequelae in autologous breast reconstruction. METHODS  A comprehensive systematic review of the published literature was conducted using Ovid Medline/PubMed database without timeframe limitations, in compliance with the guidelines outlined in the Preferred Reporting Items for Systematic reviews and Meta-Analyses. Inclusion criteria were selected for studies reporting objective outcomes of pain modulation in autologous breast reconstruction. Articles for inclusion were stratified based on intervention.