Jamisonlindgaard4445

As highlighted, carbon nanomaterials, especially graphene and carbon nanotubes, have great potential for fabricating electro-active structures due to their exceptional electrical and surface properties, opening new routes for more efficient tissue engineering approaches.This research evaluates the mechanical properties of hybrid adhesive bonds with various 100% cotton fabrics in static and quasi-static conditions and the influence of alkali surface treatment (NaOH) of the cotton fabrics on the mechanical properties. Biological fibers in polymers are characterized by low wettability with the matrix, which decreases mechanical properties. Adhesive bonds usually operate in cyclic stress, which causes irreversible failure before maximal strength. In this paper, a quasi-static test was used to load the adhesive bonds in 5-50% (192-1951 N) and 5-70% (192-2732 N) intervals with 1000 cycles. The results of SEM analysis showed good wettability of alkali treated cotton fabric with NaOH solution in hybrid adhesive bonds. The static test proved the influence of reinforcing cotton fabrics on shear tensile strength against pure resin, i.e., sample Erik up to 19% on 14.90 ± 1.15 MPa and sample Tera up to 21% on 15.28 ± 1.05 MPa. The adhesive bonds with pure resin did not resist either quasi-static tests. Reinforcing cotton fabrics resisted both quasi-static tests, even shear tensile strength increases up to 10% on 16.34 ± 1.24 MPa for the fabric Erik. Human cathelicidin The results of strain difference of adhesive bonds with Tera and Erik confirmed that a lower value of the difference during cyclic loading positively influenced the ultimate shear tensile strength.Semi-rigid composites of polyurethane foams (SRPUF) modified with the addition of keratin flour from poultry feathers and flame retardant additives were manufactured. Ten percent by mass of keratin fibers was added to the foams as well as halogen-free flame retardant additives such as Fyrol PNX, expandable graphite, metal oxides, in amounts such that their total mass did not exceed 15%. Thermal and mechanical properties were tested. Water absorption, dimensional stability, apparent density and flammability of produced foams were determined. It was found that the use of keratin fibers and flame retardant additives changes the foam synthesis process, changes their structure and properties as well as their combustion process. The addition of the filler made of keratin fibers significantly limits the amount of smoke generated during foam burning. The most favorable reduction of heat and smoke release rate was observed for foams with the addition of 10% keratin fibers and 10% expandable graphite. Systems of reducing combustibility of polyurethane foams using keratin fillers are a new solution on a global scale.An automatic accurate T-wave end (T-end) annotation for the electrocardiogram (ECG) has several important clinical applications. While there have been several algorithms proposed, their performance is usually deteriorated when the signal is noisy. Therefore, we need new techniques to support the noise robustness in T-end detection. We propose a new algorithm based on the signal quality index (SQI) for T-end, coined as tSQI, and the optimal shrinkage (OS). For segments with low tSQI, the OS is applied to enhance the signal-to-noise ratio (SNR). We validated the proposed method using eleven short-term ECG recordings from QT database available at Physionet, as well as four 14-day ECG recordings which were visually annotated at a central ECG core laboratory. We evaluated the correlation between the real-world signal quality for T-end and tSQI, and the robustness of proposed algorithm to various additive noises of different types and SNR's. The performance of proposed algorithm on arrhythmic signals was also illustrated on MITDB arrhythmic database. The labeled signal quality is well captured by tSQI, and the proposed OS denoising help stabilize existing T-end detection algorithms under noisy situations by making the mean of detection errors decrease. Even when applied to ECGs with arrhythmia, the proposed algorithm still performed well if proper metric is applied. We proposed a new T-end annotation algorithm. The efficiency and accuracy of our algorithm makes it a good fit for clinical applications and large ECG databases. This study is limited by the small size of annotated datasets.The development of nanocomposite hydrogels that take advantage of hierarchic building blocks is gaining increased attention due to their added functionality and numerous biomedical applications. Gathering on the unique properties of these platforms, herein we report the synthesis of bioactive nanocomposite hydrogels comprising naringin-loaded salmon-derived lecithin nanosized liposomal building blocks and gelatin methacryloyl (GelMA) macro-sized hydrogels for their embedding. This platform takes advantage of liposomes' significant drug loading capacity and their role in hydrogel network reinforcement, as well as of the injectability and light-mediated crosslinking of bioderived gelatin-based biomaterials. First, the physicochemical properties, as well as the encapsulation efficiency, release profile, and cytotoxicity of naringin-loaded nanoliposomes (LipoN) were characterized. Then, the effect of embedding LipoN in the GelMA matrix were characterized by studying the release behavior, swelling ratio, and hydroat these soft nanoparticles can play an important role in bioengineering bioactive nanocomposites for bone tissue engineering in the foreseeable future.Antibacterial multi-layered patches composed of an oxidized bacterial cellulose (OBC) membrane loaded with dexpanthenol (DEX) and coated with several chitosan (CH) and alginate (ALG) layers were fabricated by spin-assisted layer-by-layer (LbL) assembly. Four patches with a distinct number of layers (5, 11, 17, and 21) were prepared. These nanostructured multi-layered patches reveal a thermal stability up to 200 °C, high mechanical performance (Young's modulus ≥ 4 GPa), and good moisture-uptake capacity (240-250%). Moreover, they inhibited the growth of the skin pathogen Staphylococcus aureus (3.2-log CFU mL-1 reduction) and were non-cytotoxic to human keratinocytes (HaCaT cells). The in vitro release profile of DEX was prolonged with the increasing number of layers, and the time-dependent data imply a diffusion/swelling-controlled drug release mechanism. In addition, the in vitro wound healing assay demonstrated a good cell migration capacity, headed to a complete gap closure after 24 h. These results certify the potential of these multi-layered polysaccharides-based patches toward their application in wound healing.