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Simulations confirm HNVf as a long-term opportunity for fire suppression (up to 30,000 ha of additional suppressed areas between 2031 and 2050 in comparison to rewilding scenario) and for conservation (benefiting around 60% of species). Rewilding benefits some species (20%), including critically endangered, vulnerable and endemic taxa, while several species (33%) also profit from open habitats created by fire. Although HNVf remains the best scenario, rewilding reinforced by low fire suppression management may provide a nature-based solution when societal support through agricultural policies fails.Pyrrolizidine alkaloids (PA)s are natural toxins produced by a variety of plants including ragwort. The PAs present a serious health risk to human and livestock. Although these compounds have been extensively studied in food and feed, little is known regarding their environmental fate. To fill this data gap, we investigated the occurrence of PAs in ragwort plants, soils and surface waters at three locations where ragwort was the dominant plant species to better understand their environmental distribution. The concentrations of PAs were quantified during the full growing season (April-November) and assessed in relation to rain events. PA concentrations ranged from 3.2-6.6 g/kg dry weight (dw) in plants, 0.8-4.0 mg/kg dw in soils, and 6.0-529 μg/L in surface waters. Maximum PA concentrations in the soil (4 mg/kg) and water (529 μg/L) were in mid-May just before flowering. The average distribution of PAs in water was approximately 5 g/10,000 L, compared to the average amounts present in ragwort (506 kg/ha), and soil (1.7 kg/ha). In general, concentrations of PAs increase in the soil and surface water following rain events.An increasing number of research shows that long non-coding RNA plays a key role in many important biological processes. However, the number of disease-related lncRNAs found by researchers remains relatively small, and experimental identification is time consuming and labor intensive. In this study, we propose a novel method, namely HAUBRW, to predict undiscovered lncRNA-disease associations. First, the hybrid algorithm, which combines the heat spread algorithm and the probability diffusion algorithm, redistributes the resources. Second, unbalanced bi-random walk, is used to infer undiscovered lncRNA disease associations. Seven advanced models, i.e. BRWLDA, DSCMF, RWRlncD, IDLDA, KATZ, Ping's, and Yang's were compared with our method, and simulation results show that the AUC of our method is more perfect than the other models. In addition, case studies have shown that HAUBRW can effectively predict candidate lncRNAs for breast, osteosarcoma and cervical cancer. Therefore, our approach may be a good choice in future biomedical research.The aim of this article is to analyze the conceptual structure underlying the models of obesity prevention implemented in Argentina, Brazil, and Spain. In their culturally distinct but epidemiologically similar contexts, the three countries have devised strategies that reproduce global diagnoses of the causes of obesity and replicate some of the measures proposed at the global level. While so-called "obesogenic environments" are considered primarily responsible for these tendencies, efforts to raise awareness about food and nutrition tend to promote self-monitoring and behavior rationalization as the main tools for achieving changes in diet and physical activity. Although a variety of measures have been proposed at the local level, they have been less diverse in terms of their nature and scope, barely taking into account the constraints that hinder the adoption of healthy lifestyles. In contexts of social and food precarity, this has meant neglecting the social groups with the highest prevalence of obesity.In Brazil, the provision of mental health care in primary care centers has gained strategic importance, as it ensures that users will be able to attend these services within their communities, and empathy is a key aspect in the development of the doctor-patient relationship. The aim of this study was to identify characteristics related to empathy in physicians who work in primary care centers and who provide care to individuals with mental disorders. Qualitative research was carried out in 2016, based on semi-structured interviews with eight general and family physicians. Material from the interviews was analyzed using content analysis techniques and three categories emerged empathy in the active listening of the physician, strategies that allow for better patient care, and the mobilization of emotions. The use of empathy is intrinsically linked to the resolutive capacity of care, and the characteristics identified were active listening, resource management, and the development of methods to overcome the structural obstacles of daily routines.Challenges are in line with the risk-taking practices frequent in child and youth culture. However, online challenges take on new meanings when mediated by digital sociability. To analyze this phenomenon, 122 challenge videos in Portuguese that had been made by Brazilian children or adolescents were recovered from the YouTube platform, of which 35 were selected and transcribed. Twelve types of challenges were analyzed; all involved potential self-inflicted injuries to participants, with risks ranging from minor to lethal. The discourse analysis led to an interpretation based on the theory of self-image and ethos. Online challenges appear as a powerful communicative resource to reaffirm belonging, recognition, and audience adherence, and so constitute a media strategy adopted by youth in the construction of an Internet-mediated identity in which risk and violence are decisive devices in building a self-image capable of retaining an audience. The enunciator's body sacrifice assumes a bargaining role in this media adherence.This article argues for the construction of a new institutional hegemony with a rhizomatic design based on health centers with direct relations to a network of hospitals with increasing levels of complexity, which are put at the service of these health centers and not the other way around. The proposal for these centers includes community-based teams of workers carrying out humanized practice centered on the shift from health services to care within the community, respecting the particularities and idiosyncrasies of its residents and their cultures. First, a brief historical revision of the genesis of health centers and of hospitals is presented. Second, technical recommendations to restructure models of care and institutional organization in the health field are put forth, and technical-political proposals for this new institutional hegemony are outlined, which are developed along three dimensions organization, policy, and service and care processes. Lastly, some barriers to the construction of this new hegemony are identified.This article analyzes the results of a descriptive, qualitative study carried out in 2018 on the mental healthcare needs of Latin American refugees and asylum seekers in Chile, through the perspectives of refugees and asylum applicants (n=8), healthcare professionals responsible for delivery of care (n=4), and members of civil society organisations involved in this area (n=2). Our findings indicate that despite Chile's commitment to international treaties in this regard, little has been achieved in safeguarding the right to access to mental health care, understood as part of the universal right to health care access. This article documents barriers to mental health care access for migrants applying for asylum and refugee status. Post-migration stress factors may also increase the risk of emotional disorders within this group of people. https://www.selleckchem.com/products/bgb-283-bgb283.html Mental healthcare providers and teams are often not equipped with the tools to deal with the psychological consequences arising from the situations of violence and persecution associated with forced migration. Our study discusses the need to strengthen the link between mental health care - as a fundamental human right - and the right to international protection.Co-management is one of the guidelines found in Brazil's National Humanization Policy, a policy that promotes the creation of collective spaces for its construction. Based on a social constructionist approach, qualitative research was carried out between 2015 and 2018 in order to describe and analyze the relational dynamics established in two primary care facilities - a Primary Care Unit and a Family Health Center - with the aim of analyzing organizational cultures and the social construction of co-management. Research was carried out in two phases fieldwork and interviews. Given that the Family Health Center presented a culture closer to the idea of co-management, we describe and analyze factors contributing to this dynamic. Whereas in the case of the Primary Care Unit, which proved to be farther from co-management, we look at obstacles. Our goal is to demonstrate the complex and fluid nature of relational dynamics, and to show that their transformation requires that efforts be tailored to each specific context, and therefore the "implementation" of collective spaces is not sufficient on its own to generate effective co-management.The objective of this article is to describe births according to their distribution by day of the week in order to characterize the scheduled or non-scheduled aspect of the labor and delivery process. A descriptive epidemiological study of the temporal distribution of the days of the week on which births occurred in the Autonomous City of Buenos Aires was carried out for the period 2004-2013, based on the Statistical Reports of Live Births database of the Directorate of Statistics and Health Information at the National Ministry of Health. The following variables were analyzed using descriptive statistics establishment (public or private sector), gestational age, maternal age, and mother's level of education. The analysis reveals that births decrease significantly on Saturdays and Sundays in both public and private establishments, with a greater decrease being observed in private establishments. Births at week 37 are more frequent in private establishments and decrease on non-working days. For mothers with higher levels education, fewer births occurred on weekends. Analyzing the day of the week on which births occur reveals the medicalization of the delivery process and could indicate that the scheduling and induction of births occur in private establishments to a greater extent than in public establishments.In order to explore the impacts of nitrogen fertilizer and straw returning methods on N2O emissions, a two-factor split-zone design was adopted for experimentation under the winter wheat-summer maize rotation model in the Guanzhong area of Shanxi, China. The main areas of interest were conventional nitrogen (G) and reduced nitrogen (70% G); the sub-areas were straw no return (N), straw return (S), and straw return + biochar (SB); we analyzed their impacts on N2O emissions and crop yield, and the relationships with related impact factors. The results showed that the N2O emissions peaks appeared in the wheat season and maize season treatments within 5-16 days after fertilization, and also appeared after rainfall. The N2O flux was significantly and positively correlated with soil temperature and NH4+-N content. Regardless of the wheat season, maize season, or annual total N2O emissions, the 70% GSB treatment was the lowest and the GS treatment was the highest. At the same level of nitrogen application, S treatment increased N2O emissions, SB treatment could reduce N2O emissions, both S and SB treatments could significantly increase crop yields, and SB production increased more; 70%G-level annual N2O emissions, when compared with the G level, had been reduced by 40% to 48%, while the yield has not decreased significantly.