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RESULTS The success rate for the SW-assisted STS transfers was significantly higher than for the Five-Chair Stand Test (93.3 ± 12.9% vs 54.5 ± 50.6%, P less then  0.001). User satisfaction was high (Tele-healthcare Satisfaction Questionnaire-Wearable Technology 62.5 ± 11.2 points). The success rate with the STS assistance system was not significantly associated with any participant characteristics. selleck chemicals llc Higher body mass index was a significant independent predictor of higher user satisfaction. CONCLUSIONS The SW-integrated STS assistance system can provide effective STS support with high user satisfaction for a wide range of potential users. Our findings suggest the high potential of the STS assistance system for promoting mobility, independence and quality of life for older adults with motor impairments. Geriatr Gerontol Int 2020; •• ••-••. © 2020 The Authors. Geriatrics & Gerontology International published by John Wiley & Sons Australia, Ltd on behalf of Japan Geriatrics Society.BACKGROUND This study assessed variations in SAA and 8-OHdG in patients with senile early cognitive impairment (CI). MATERIAL AND METHODS The subjects were divided into 3 groups 121 patients with mild cognitive impairment (MCI), 131 with Alzheimer's disease (AD), and 100 healthy persons that underwent physical examinations during the same period (Control). These groups were evaluated by MMSE and MoCA, and the SAA and 8-OHdG levels in these groups were tested using ELISA sandwich technique. RESULTS The AD group had significantly higher TG and ApoB levels, followed by the MCI and Control groups, respectively (P less then 0.05). The MCI group had the highest HDL-C level significantly, while the Control group had the lowest (P less then 0.05). The Control (normal) group had significantly higher MoCA and MMSE scores, followed by the MCI group and the AD group (P less then 0.05). The Control (normal) group had significantly lower SAA and 8-OHdG levels, followed by the MCI group and the AD group (P less then 0.05). The MoCA and MMSE scores and serum 8-OHdG and serum SAA levels in the 3 groups were negatively correlated, but their SAA and 8-OHdG levels were positively correlated. CONCLUSIONS SAA and 8-OHdG in the MCI and AD groups were highly expressed but had an inverse correlation with cognitive function scores (hereafter referred to as CFs scores). They can also be applied as test indicators of MCI. We also detected an apparent link between SAA and 8-OHdG.A 50-y-old male in otherwise good health was diagnosed with severe osteoporosis with a lumbar spinal t score of -3.8. Further testing revealed no underlying causes other than a family history of the disease. He was placed on a trial regimen of 450 mg Cyplexinol twice daily for 4 mo. Repeat DEXA scans after 4 mo of this therapy showed an improved lumbar spinal t score of -3.3, the first time that improvement in t scores has been demonstrated in this short amount of time. Cyplexinol, the first orally consumable demineralized bone matrix consisting of a naturally derived bone morphogenetic protein complex, may be a beneficial alternative to conventional treatments for osteoporosis with an ability to reverse bone mineral density loss in as little as 4 mo.Background Biomedical research has recently incorporated bioceramics applications into new health care approaches. Objective This study evaluated the effect of far infrared-emitting bioceramics wraps in the treatment of intermittent claudication. Methods This is a randomized double-blind placebo-controlled pilot study. Thirty-five patients met the criteria and were randomized into either control (placebo wraps) or bioceramics group (far infrared emitting-ceramics wraps) and assessed over a 90-day period for the following outcomes six-minute walk test (6MWT), ankle-brachial index (ABI), Flow-mediated arterial dilation (FMD), quality of life and claudication. Oxidative stress and inflammatory biomarkers were measured in plasma of patients. Results Intervention induced a decrease in oxidative stress, with significant lower levels of reactive substances to thiobarbituric acid (TBARS), as well as increase in superoxide dismutase and catalase enzyme activities. There was an increase in the environment subscale of the quality of life questionnaire. No statistically significant differences were found in the inflammatory cytokines, 6MWT, ABI and FMV evaluations. Conclusions In Sum, FIR treatment improved oxidative stress profile and quality-of-life of patients with intermittent claudication. The study was registered into the ensaiosclinicos.gov.br (Registro Brasileiro de Ensaios Clínicos [ReBEC]) (RBR-7nr6sy register number).No Abstract Available.in English, Portuguese Os autores descrevem um caso clínico de corecção de endoleak tipo 1A após EVAR com recurso a endo-âncoras. Trata-se de uma doente de sexo feminino, de 85 anos, com antecedentes de hipertensão, dislipidemia, insuficiência renal crónica e múltiplas intervenções abdominais (apendicectomia, colecistectomia clássica e histerectomia). A doente foi observada em consulta externa por AAA com 7,5 cm, colo de 14 mm, angulado. Submetida a EVAR com colocação de endoprótese Medtronic® Endurant II sem intercorrências de relevo. Decorrido um mês após o procedimento a angiotomografia computorizada (ATC) abdomino-pélvica revelou endoleak tipo 1A. Programada a correção do endoleak, que consistiu em stenting da artéria renal esquerda (a mais baixa), colocação de cuff aórtico proximal e de 9 endo-âncoras (Sistema APTUS®), com resultado final satisfatório. A ATC de controlo após a reintervenção mostrou permeabilidade das artérias renais e da endoprótese, exclusão aneurismática e ausência de endoleaks.in English, Portuguese Objetivo Determinar se a transferência inter-hospitalar afecta adversamente a sobrevida de doentes com rutura de aneurisma da aorta abdominal (rAAA), submetidos a cirurgia convencional. Métodos Efetuamos uma análise retrospetiva dos rAAA tratados sequencialmente por cirurgia convencional, num centro de referenciação terciária, no período compreendido entre janeiro 2008 e dezembro de 2014. Os casos foram divididos entre os que se apresentram diretamente neste centro e os que foram alvo de transferência. Analisou-se a mortalidade às 24 horas, a mortalidade aos 30 dias e, como outcomes secundários, incluíram-se o tempo de chegada ao bloco operatório, duração de internamento na unidade de cuidados intensivos (UCI) e o tempo de internamento total. Resultados Neste período, um total de 78 casos (88% do género masculino) foram submetidos a cirurgia convencional por rAAA, 69% (54 casos) transferidos de outra instituição. Ambos os grupos mostraram semelhanças nas características demográficas, beer-se à possível seleção de doentes transferidos (clinicamente estáveis) que conseguem tolerar o atraso na instituição do tratamento cirúrgico, decorrente da transferência.We report a rare case of an advanced stage thymoma with right superior pulmonary lobe, superior vena cava, innominate vein and pericardium invasion in a patient with Good's syndrome. In a multidisciplinary discussion, surgical resection was deemed the best initial approach, since invaded structures could be safely managed. The tumor was fully resected and included partial resection of the superior pulmonary lobe, superior vena cava and innominate vein. The encircled right phrenic nerve was dissected from the tumor and preserved. The superior vena cava and innominate vein were reconstructed using autologous pericardium patch. Immunoglobulin replacement and radiotherapy were initiated afterwards. No signs of relapse at 6 months follow-up. In such advanced cases, aggressive surgical intervention should be considered as first line of treatment, as long as full resection can be anticipated, since complete resection is the leading factor for long-term prognosis.OBJECTIVES Thymic cysts represent 1-3% of all tumors in the anterior mediastinum, but their knowledge is important during the differential diagnosis of a mediastinal mass. METHODS We describe the case of a 52 years old woman, totally asymptomatic, with an incidental diagnosis of a mediastinal mass at thoracic computed tomography evaluation. RESULTS Thoracic magnetic resonance showed an heterogeneous mass with approximately 3,6 cm, at the anterior mediastinum. For diagnostic clarification, surgical excision was performed. The histopathological exam revealed an epidermoid thymic cyst. CONCLUSION Surgical excision and histopathological evaluation allow definite diagnosis of this tumor, associated with a good prognosis.Bioprosthetic valve thrombosis is a rare complication. Left atrial dilatation, atrial fibrillation, hypercoagulability and low cardiac output are known risk factors. We report the case of a patient undergoing a bioprosthetic mitral valve replacement who required postoperative circulatory support with extracorporeal membrane oxygenation and presented acute bioprosthetic valve thrombosis. Some aspects regarding pathogenesis, diagnosis and treatment are discussed.Takayasu's arteritis (TA) is a rare inflammatory vascular disease, which causes a chronic progressive pan-endarteritis involving the aorta and its main branches, leading to persistent and uncontrolled hypertension and symptoms related to ischemia such as claudication, visual disturbances, stroke and transient ischemic attack. link2 Limited information is available concerning anaesthetic management. link3 We present the successful anaesthetic management of a 55 years old woman with TA scheduled for mitral valve replacement, tricuspid valve annuloplasty and coronary artery bypass grafting (CABG). The choice of anaesthetic technique took into consideration mainly the maintenance of blood pressure in the intraoperative and postoperative periods. According to our monitoring records, we can say that our choice enabled a safe and stable anaesthetic procedure.BACKGROUND/OBJECTIVES The success of the orthopaedic treatment is closely related to the patient's skeletal maturation. This study aimed to evaluate the midpalatal suture (MPS), the zygomaticomaxillary suture (ZMS) maturation, and the closure degree of the spheno-occipital synchondrosis (SOS) in patients of different age groups. The presence of a correlation between these parameters and the palatal dimensions was also verified. SUBJECTS/METHODS The study was based on computed tomography images of 314 patients between 7 and 30 years of age with no orthodontic treatment history. The images were retrieved from the archive of the Radiology Department of Bezmialem Vakif University Hospital and divided into six groups according to the patient's age 7-10, 11-13, 14-16, 17-20, 21-25, and 26-30 years. The maturation scores of ZMS, SOS, and MPS were determined, and palatal thickness and length were recorded. The data were analysed by using Statistical Package for Social Sciences for Windows 22.0. RESULTS A positive relationship was found between SOS closure degree and MPS/ZMS maturation (MPS-ZMS r = 0.816, MPS-SOS r = 0.736, ZMS-SOS r = 0.868, P = 0.000). The degrees of ZMS and MPS maturation were significantly increased as the SOS closure degree increased. The MPS maturation score was significantly lower in patients with a short and thick palate (MPS-palatal thickness r = 0.405, MPS-palatal length r = 0.387, P = 0.000). CONCLUSIONS A positive correlation indicated the simultaneous progress in the maturation of the SOS, MPS, and ZMS. Moreover, the ANS-PNS length increase was found to be correlated with the increase of the MPS, ZMS, and SOS maturation scores. In contrast, a negative correlation was observed between the palatal thickness and the maturation stage of these structures. © The Author(s) 2020. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email journals.permissions@oup.com.

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