Hougaardstorm5051

bryo transfer. CONCLUSIONS On average, aneuploidy is detected in 34% of embryos when performing a single blastocyst biopsy derived from patients carrying or affected by an inherited disorder. Accordingly, when screening for aneuploidy, the risk of experiencing a cycle with no transferable embryos increases. Current available data on the clinical effect of preimplantation genetic testing for aneuploidy performed concurrently with preimplantation genetic testing for inherited disorders are sparse, rendering the clinical effect from preimplantation genetic testing for aneuploidy difficult to access. © 2020 Nordic Federation of Societies of Obstetrics and Gynecology.Low biomass microbiome has an increasing importance in today's fertility studies. There are more and more indications for incorporating upper gynecological tract microbiome content in patients diagnostic and in vitro fertilization process, as doing so may help to evaluate chances for a positive outcome. An abnormal endometrial microbiota has been associated with implantation failure, pregnancy loss, and other gynecological and obstetrical conditions. Furthermore it has been shown, that using molecular methods in addition to routine diagnostics may help diagnose chronic endometritis or even indicate cancerogenic changes. Understanding the significance of microbiome in endometrium may completely change therapeutic approach in treatment of this part of reproductive tract. Next generation sequencing (NGS) has allowed to isolate culturable and unculturable bacteria from female reproductive tract and is a cheaper and quicker alternative for other widely known and used methods.Early Postpartum Hemorrhage (EPH) is one of the leading causes of postpartum mortality. It is defined as blood loss of at least 500 mL after vaginal or 1000 mL following cesarean delivery within 24 hours postpartum. The following paper includes literature review aimed to estimate the incidence and predictors of early postpartum hemorrhage (EPH). Available prevention and treatment methods were also assessed. The inclusion criteria for the study were met by 52 studies. The exact frequency of EPH in different populations varies from 1.2% to 12.5%. Maternal, pregnancy-associated, laborcorrelated and sociodemographic risk factors seem to be important predictors of EPH. In these cases appropriate prophylaxis should be considered. However, EPH may occur without previous risk factors. The main reason for EPH is uterine atony which contributes to up to 80% of cases of postpartum hemorrhage (PPH). Other common reasons for PPH include genital tract injuries, placenta accreta or coagulopathies. Interestingly, the majority of uterotonics seem to have a similar effect. However, carbetocin seems to be the most effective in certain situations. Appropriate diagnosis of EPH is the most important issue. The treatment should be causative. The first-line treatment should include uterotonics. Surgical interventions, if required, should be performed without delay, although preoperative uterine tamponade should be considered due to its high effectiveness. Medical staff training in medical simulation centers is an important factor that improves the outcomes of EPH treatment. It provides adaptation to hospital protocols, team work improvement, self-confidence building, more accurate blood loss evaluation and reduced perception of stress. The implementation of systematic trainings provides better outcomes in the future.The number of immunocompromised patients is rising, and immunodeficiency is an independent risk factor for the development of premalignant and malignant lesions of the cervix and anogenital tract. The aim of this review was to summarize and update data on human papilloma virus (HPV) infections and HPV-based anogenital lesions detected in patients who were immunocompromised due to both organ transplantation and human immunodeficiency virus (HIV) infection. The incidence of HPV infections among solid organ recipients and HIV positive females is reported to be significantly higher when compared with age-matched healthy controls- i.e. higher by up to 65% and 46.6% respectively, vs 38% in the controls. These infections are also more often chronic, high risk HPV and multitype. Data suggest that HPV infections in these patients might not only occur more frequently, but that the course of the infection might also lead to faster oncogenesis. However, the treatment options for malignancies are limited; and this implies the need for intense primary and secondary prevention regimens. As infections with HPV types other than 16 and 18 and multitype infections are particularly frequently discovered in immunocompromised patients, they would probably benefit most from a nonavalent vaccine. Gynecological screening should be performed annually, including cervical smears and/ or HPV testing. read more In the group of non-responders, self-sampling methods should be considered.OBJECTIVES Internal Iliac artery ligation (IIAL) is an effective life-saving method to control obstetric hemorrhage, and a hysterectomy can often be avoided. A standard ligation procedure requires wide tissues dissection incision in the peritoneum lateral to and parallel with the ureter. That can be traumatic and is difficult in practice what results in a rare use of IIAL in surgical emergency. As an alternative a novel, small invasive technique was used, which protocol is attached to the paper as a video presentation file. MATERIAL AND METHODS Forty-five women treated by Internal Iliac Artery ligation for postpartum haemorrhage. In 27 patients (Cohort A) standard IIAL procedure by Kelly's method was used. In the remaining 18 patients (Cohort B) a novel, small invasive technique was performed. Time of both surgical procedures of IIAL was measured. RESULTS Time of Standard technique of IIAL vs Novel small invasive technique of IIAL 34 (26-41) min. vs 13 (8-16) min. p less then 0.001. CONCLUSIONS The presented novel small invasive technique of Internal Iliac artery ligation can be an easier and safe alternative for standard ligation procedure.OBJECTIVES Mood disturbances are the most prevalent mental health problems in expectant parents. The knowledge about the factors which increase the risk of perinatal depression is insufficient, especially in fathers. The aims of the present study were to estimate the prevalence and to compare mean levels of antenatal depression and anxiety as well as to examine the relationship between the risk for depression and anxiety in primiparous Polish parents. MATERIAL AND METHODS 250 parental couples participating in antenatal classes took part in the study. Depression and anxiety were measured with the Edinburgh Postnatal Depression Scale (EPDS) and the State-Trait Anxiety Inventory (STAI), respectively. Paired t-test with bootstrapping was applied to compare parental EPDS, as well as STAI raw scores. Pearson correlation coefficients were calculated for depression and anxiety scores for women and men separately. The factors predictive for the increased risk of depression were investigated with the use of a multivariate logistic regression analysis.