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Therefore, surgeons should choose the technique based on their skills and the patient's expectations of surgery, such as cosmesis and time to recovery. More studies are needed to evaluate complications such as adhesive capsulitis and cramping, as well as to compare duration of surgery and recovery time for each technique.

Level I, therapeutic study.

Level I, therapeutic study.

A 68-year-old male, status post revision right reverse total shoulder arthroplasty (RTSA) for periprosthetic fracture, suffered a periprosthetic joint infection necessitating 2-stage revision. Imaging revealed 8.6 cm of ipsilateral proximal humeral bone loss (PHBL) including loss of the greater and lesser tuberosities. Darovasertib A 2-stage revision was performed using an antibiotic spacer, followed by a custom long-stem RTSA for definitive reconstruction. Two years postoperatively, the patient had significantly improved pain and functional range of motion.

Custom long-stem RTSA could serve as a potentially viable reconstructive option in patients with severe PHBL.

Custom long-stem RTSA could serve as a potentially viable reconstructive option in patients with severe PHBL.

The authors present 3 adolescent athletes who presented with stress fractures in their lower extremities, initially diagnosed as tumors. All 3 patients received an inconclusive magnetic resonance imaging before referral; fractures were confirmed on radiographs and computed tomography. All were found to have vitamin D insufficiency.

Vitamin D insufficiency is a global epidemic mainly focused on adults and young-adult athletes. These case reports raise concerns about a growing prevalence of vitamin D insufficiency in adolescents, the potential risk of stress fracture, and the need for screening and possible supplementation in adolescent athletes to improve their bone health.

Vitamin D insufficiency is a global epidemic mainly focused on adults and young-adult athletes. These case reports raise concerns about a growing prevalence of vitamin D insufficiency in adolescents, the potential risk of stress fracture, and the need for screening and possible supplementation in adolescent athletes to improve their bone health.

A 70-year-old woman pedestrian struck by a motor vehicle presented with multiple orthopaedic injuries including a humeral head fracture dislocation with a large segment of humeral head located in the mediastinum. Thoracic surgery personnel performed a minimally-invasive video-assisted thoracoscopic extraction of the humeral head, and the patient underwent subsequent reverse total shoulder arthroplasty.

Intramediastinal displacement of the humeral head is a rare, yet serious traumatic injury that necessitates early recognition and comanagement with cardiothoracic or thoracic surgery. Early thoracic intervention to extract the humeral head and replacement arthroplasty is an effective treatment modality.

Intramediastinal displacement of the humeral head is a rare, yet serious traumatic injury that necessitates early recognition and comanagement with cardiothoracic or thoracic surgery. Early thoracic intervention to extract the humeral head and replacement arthroplasty is an effective treatment modality.

Brentuximab vedotin (BV) is a potent therapeutic option for CD30-positive cutaneous T-cell lymphoma. Unlike existing studies, BV and other therapeutic procedures were frequently combined for our patients. In this context, the study aims to analyze the effectiveness and safety of BV in a real-world setting.

This is a retrospective monocentric study analyzing treatment outcomes for patients with CD30-positive cutaneous T-cell lymphoma treated with BV.

26 patients (median age 67 years) were included in the study. Patients were treated with 1.8 or 1.2mg/kg b.w. Complete remission (CR) was reached in 30.8% of the patients, and the objective response rate (ORR) was 84.6%. Side effects were seen in 19 of the 26 patients. As a reaction to progressive disease (PD) under BV monotherapy, we included skin-directed procedures such as tumor excision, local radiotherapy, and PUVA for six patients. We re-stabilized the disease and maintained the line of therapy without additional toxicities for a median of seven months longer using this concept.

Addition of skin-directed therapies (SDT) after disease progression under BV monotherapy could stabilize the disease's continuous advancement or even lead to partial response, thereby extending the time until the next therapeutic escalation.

Addition of skin-directed therapies (SDT) after disease progression under BV monotherapy could stabilize the disease's continuous advancement or even lead to partial response, thereby extending the time until the next therapeutic escalation.

To measure surface roughness before and after wear-tests of two different prefabricated composite veneers and compare them to ceramic veneers and human dental enamel.

Roughness (Ra-values) of two prefabricated composite veneers (Visalys Veneer Chairside (VIS) and Componeer (COM)) were compared to lithium disilicate Veneers (e.max CAD) and dental enamel (DENT) in vitro. In total n = 45 specimens per material and enamel samples were used for wear-tests. Wear-out tests were conducted by abrasion tests with a toothbrush simulator (22,000 strokes/ 100 g load; approximately equal to two years of cleansing) and erosion tests were carried out using citric acid (pH 1.57). Ra- and Sa-values were detected by white light interferometer before and after wear-tests. Data were analyzed with ANOVA followed by Games-Howell post hoc test and t-test (α = 0.05).

At baseline the lowest Ra- and Sa-values were found in VIS (Ra 0.01 µm; Sa 0.04 µm) while DENT revealed significantly higher surface roughness (Ra 0.11 µm, p < 0.05; Sa 0.30, p = 0.186). COM had significantly higher Ra-values (Ra 0.10 µm; Sa 0.22 µm) after abrasion, while e.max CAD was most resistant to the treatments (Ra 0.01 µm, p < 0.05; Sa 0.05 µm, p < 0.05). Compared to DENT all veneers were significantly less affected by citric acid (p < 0.001).

Prefabricated composite veneers have demonstrated less wear after abrasion and erosion tests compared to DENT, nevertheless, they revealed more wear compared to e.max CAD.

Prefabricated composite veneers have demonstrated less wear after abrasion and erosion tests compared to DENT, nevertheless, they revealed more wear compared to e.max CAD.

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