Helbobay3683

© 2020 John Wiley & Sons Australia, Ltd.Person-centred care is a relatively new orthodoxy being implemented by modern hospitals across developed nations. Research demonstrating the merits of this style of care for improving patient outcomes, staff morale and organizational efficiency is only just beginning to emerge. In contrast, a significant body of literature exists showing that attainment of person-centred care in the acute care sector particularly, remains largely aspirational, especially for older people with cognitive impairment. In previous articles, we argued that nurses work constantly to reconcile prevailing constructions of time, space, relationships, the body and ethics, to meet expectations that the care they provide is person-centred. In this article, we explore key concepts of neo-liberal thought which forms an important back-story to the articles. Economic concepts, "efficiency" and "freedom" are examined to illustrate how nurses work to reconcile both the repressive and productive effects of economic power. We conclude the article by proposing a new research agenda aimed at building a more nuanced understanding of the messy actualities of nursing practice under the influences of neo-liberalism, that illuminates the compromises and adaptations nurses have had to make in response to economic power. © 2020 John Wiley & Sons Ltd.OBJECTIVE To review medication-related criteria within validated frailty tools. METHODS Narrative review of validated frailty assessment tools. Frailty tools were identified from recently published reviews; each tool was reviewed to determine whether any medication-related criteria were included and how these criteria contributed to the scoring/assessment of frailty. RESULTS Eight out of 16 validated frailty tools included medication-related criteria. The majority of criteria were a numerical cut-off of number of medications taken; however, the specific cut-off was not consistent. CONCLUSION Inclusion of medication-related criteria in frailty tools is highly variable. Future research is required to determine whether incorporation of medication use into frailty assessment can impact outcomes in terms of frailty prevention and treatment. © 2020 AJA Inc."My motto is 'Continual dropping wears away the stone'. If I could be a piece of lab equipment, I would be a single-crystal X-ray diffractometer …" Find out more about Shilie Pan in his Author Profile. © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.BACKGROUND With the increasing incidence of multidrug-resistant (MDR) organisms and high mortality rates associated with these infections, we describe the spectrum of the major drug-resistant pathogens identified in fecal surveillance, and re-visit the use of fecal surveillance in predicting infection with these organisms post-allogeneic stem cell transplant. METHODS Data from allogeneic stem cell transplant recipients with common drug-resistant strains of bacteria in fecal surveillance (Escherichia coli, Klebsiella spp., and Enterococcus spp.) were compared with recipients who did not have the same in fecal surveillance cultures. Baseline characteristics and post-transplant outcomes including similar drug resistance in blood cultures, severe sepsis, and 100-day transplant-related mortality were compared. Multivariate analysis using logistic regression model was used to determine independent predictors of outcome. RESULTS In 232 transplants, the prevalence of common drug-resistant isolates in fecal surveillanhen  .001) retained significance in predicting 100-day mortality. CONCLUSION Organisms resistant to 3rd generation cephalosporins are frequently seen on fecal surveillance in the pre-transplant setting and are associated with a higher incidence of drug-resistant organisms in subsequent blood cultures (not limited to the same drug resistance pattern as seen in fecal surveillance). Drug-resistant organisms in fecal surveillance are associated with poorer outcomes following allogeneic stem cell transplant and may be used as a guide to identify patients at risk of subsequently developing a drug-resistant organism in blood. © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd."My first experiment was burning magnesium in oxygen in junior high school … In a spare hour, I like hiking …" Find out more about Song Ye in his Author Profile. © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.Metal oxides are one of the promising candidates as electrocatalysts for electrical energy storage (EES) systems. Particularly, perovskite and pyrochlore oxides have been intensively investigated as bi-functional electrocatalysts because of their superior catalytic activities during oxygen reduction and evolution reactions. However, the origin of outstanding catalytic activities and structural changes of materials are not clearly revealed, in part due to the difficulty in identification during electrocatalysis. In this Minireview, we present a critical overview of recent progress in understanding catalytic mechanisms of perovskite and pyrochlore oxides, highlighting the innovative in situ X-ray absorption spectroscopy (XAS) analysis for electrochemical tests. © 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.Helical carbazole-based BODIPY analogues were readily synthesized via aza[7]helicenes. The structures of azahelicene-incorporated BF2 dyes were elucidated by x-ray diffraction analysis. DFT calculations revealed that the π-conjugated system expanded from the helicene moiety to the BODIPY framework. The azahelicene-fused boron complexes showed the Cotton effects and the circularly polarized luminescence (CPL) in the visible region. Furthermore, an axially chiral binaphthyl group was attached to the helically chiral dyes, which enhanced the chiroptical properties. © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.Primary Sjögren's syndrome (SS) is a systemic autoimmune disease in which exocrine organs, primarily the salivary and lacrimal glands, are targets of chronic inflammation, leading to severe dryness of eyes and mouth. Fatigue and arthralgia are also common, and extraglandular manifestations involving the respiratory, nervous and vascular systems occur in a subset of patients. selleck chemical Persistent activation of the type I interferon system, and autoreactive B and T cells with production of disease-associated autoantibodies are central to the pathogenesis. Genetic polymorphisms that associate with an increased risk of SS have been described, though the risk-increase contributed by the respective variant is generally low. It is thus becoming increasingly clear that genetics cannot alone account for the development of SS and that other, presumably exogenous, factors must play a critical role. Relatively few studies have investigated exposure to potential risk factors prior to SS disease onset. Rather, many factors have been studied in prevalent cases.