Hardindolan2681
This is the first report to describe a case of SWS associated with SRD and resolution of SRF after trabeculectomy.
This is the first report to describe a case of SWS associated with SRD and resolution of SRF after trabeculectomy.
To report a rare paradoxical development of systemic sarcoidosis in a patient taking adalimumab manifesting as multifocal choroidal infiltrates and seventh nerve palsy.
This was a single patient case report.
A 30-year-old man with a history of psoriatic arthritis on adalimumab presented with intermittent fevers and headaches. Initial infectious serology and initial ophthalmic examination were within normal limits. Over the next month, he developed a seventh nerve palsy, unilateral decreased visual acuity, and bilateral multifocal choroidal infiltrates. The patient was diagnosed with systemic sarcoidosis secondary to tumor necrosis factor alpha (TNFα) inhibitor use after a hilar lymph node biopsy. Upon treatment with high-dose oral corticosteroids, the patient's symptoms and choroidal lesions significantly improved.
This case report illustrates a rare presentation of ocular, neurologic, and systemic sarcoidosis presenting as a bilateral multifocal choroiditis and seventh nerve paresis in a patient treated with adalimumab. We highlight the importance of obtaining an ophthalmic evaluation in the management of this rare adverse effect of TNFα inhibitors.
This case report illustrates a rare presentation of ocular, neurologic, and systemic sarcoidosis presenting as a bilateral multifocal choroiditis and seventh nerve paresis in a patient treated with adalimumab. We highlight the importance of obtaining an ophthalmic evaluation in the management of this rare adverse effect of TNFα inhibitors.
To present a case of bilateral Brown syndrome who presented as a unilateral disease and then showed the disease in the fellow eye in an older age.
A 4-year-old girl presented with congenital Brown syndrome of the left eye and underwent a superior oblique weakening procedure in that eye, but then developed Brown syndrome in the right eye which required two more surgeries on the right eye to attain an acceptable alignment.
Her orbital computed tomography scan revealed that the distance between the annulus of Zinn and trochlea (Z-T distance) was 41.2 mm in both sides, which was comparatively longer than her age- and sex-matched cases. This finding can suggest a possible mechanism of Brown syndrome development in some patients.
Bilateral Brown syndrome can present as a sequential disease, and its radiologic finding may be associated with increased Z-T distance.
Bilateral Brown syndrome can present as a sequential disease, and its radiologic finding may be associated with increased Z-T distance.
To report a rare case of primary pneumosinus dilatans (PSD) and to specify the cardinal imaging findings associated with this condition.
A 20-year-old patient presented with bilateral profound visual loss as a result of primary PSD. A detailed review of clinical findings and presumed pathophysiological basis of vision loss was performed.
Other than undiagnosed primary hypothyroidism, no other abnormalities were found. With the diagnosis of PSD, the patient underwent optic nerve decompression through transnasal sphenoidotomy. However, after nine months of follow-up, no improvement in the patient's vision was attained.
Unlike previous reports of favorable visual results after sphenoidotomy and bilateral decompression of the optic nerves, vision recovery was not achieved in this case.
Unlike previous reports of favorable visual results after sphenoidotomy and bilateral decompression of the optic nerves, vision recovery was not achieved in this case.
To investigate the retinal vascular characteristics among patients with different types of inherited retinal dystrophies (IRDs).
This comparative cross-sectional study was conducted on 59 genetically confirmed cases of IRD including 37 patients with retinitis pigmentosa (RP) (74 eyes), 13 patients with Stargardt disease (STGD) (26 eyes), and 9 patients with cone-rod dystrophy (CRD) (18 eyes). Both eyes of 50 age- and sex-matched healthy individuals were investigated as controls. All participants underwent optical coherence tomography angiography to investigate the vascular densities (VDs) of superficial and deep capillary plexus (SCP and DCP) as well as foveal avascular zone area.
In RP, significantly lower VD in whole image (
= 0.001 for DCP), fovea (
= 0.038 for SCP), parafovea (
< 0.001 for SCP and DCP), and perifovea (
< 0.001 for SCP and DCP) was observed compared to controls. In STGD, VD of parafovea (
= 0.012 for SCP and
= 0.001 for DCP) and fovea (
= 0.016 for DCP) was significantly lower than controls. In CRD, the VD of parafovea (
= 0.025 for DCP) was significantly lower than controls. Whole image density was significantly lower in RP compared to STGD (
< 0.001 for SCP) and CRD (
= 0.037 for SCP). VD in parafovea (
= 0.005 for SCP) and perifovea (
< 0.001 for SCP and DCP) regions was significantly lower in RP compared with STGD. Also, foveal VD in STGD was significantly lower than RP (
= 0.023 for DCP).
Our study demonstrated lower VDs in three different IRDs including RP, STGD, and CRD compared to healthy controls. Changes were more dominant in RP patients.
Our study demonstrated lower VDs in three different IRDs including RP, STGD, and CRD compared to healthy controls. Dibutyryl-cAMP cell line Changes were more dominant in RP patients.
To investigate the availability and content of educational statements or recommendations disseminated by U. S. ophthalmologic organizations regarding perioperative management of antithrombotic agents for ophthalmic and orbital surgery, given the highly variable management of these agents by U. S. ophthalmologists and limited consensus recommendations in the literature.
National U. S. ophthalmic surgical organization websites were systematically examined for educational statements, which were reviewed for discussion of perioperative management of antithrombotic agents including antiplatelet and anticoagulant medications. A "statement" was defined as either (a) a guideline directed toward ophthalmologists or (b) a surgical/clinical educational posting directed toward ophthalmologists or patients.
Fourteen surgical organizations were identified, with eight of these publishing clinical/surgical educational statements. A total of 3408 organizational statements were identified, with 252 (7.4%) and 3156 (92.6%thrombotics may be justified.
Educational material from U. S. ophthalmologic organizations regarding perioperative management of antithrombotics is notably lacking despite the fact that ophthalmic and orbital surgeries carry unique vision-threatening hemorrhagic risks. Given these risks, as well as the medicolegal consequences of hemorrhagic complications in ophthalmic surgery, increased dissemination of educational material, and consensus statements by ophthalmic surgical organizations on the perioperative management of antithrombotics may be justified.
To evaluate medication and follow-up adherence in incarcerated patients examined at an academic glaucoma clinic, in comparison to nonincarcerated controls.
Retrospective, case-control study. Consecutive prisoners presenting for initial visits in the Glaucoma Clinic at the Illinois Eye and Ear Infirmary between December 2015 and December 2017 were included in the study. Nonincarcerated patients seen in the same Glaucoma Clinic with similar initial visit dates, age, race, sex, and disease severity were selected as controls. Glaucoma Clinic visits from each patient were reviewed until December 2018. Examination information, surgical intervention, follow-up and treatment recommendations, and patient-reported medication usage were recorded for each visit. Number of visits, loss to follow-up, follow-up delays, and medication nonadherence were studied as primary outcome measures.
Twenty-four prisoners and 24 nonincarcerated controls were included. Prisoners had an average of 2.46 ± 2.38 visits during the study period, compared to 5.04 ± 3.25 for controls (
= 0.001). Follow-up visits occurred more than 30 days after the recommended follow-up time in 57.4% (95% confidence interval [CI] 44.2%-70.6%) of prisoners, compared to 17.9% (95% CI 10.2%-25.6%) of controls (
< 0.00001). 70.8% of prisoners (95% CI 66.3-74.5%) were lost to follow-up, compared to 29.2% of controls (95% CI 25.5%-32.9%;
< 0.01). Medication nonadherence rates were similar between prisoners (13.6%; 95% CI 12.1%-15.2%) and controls (12.0%; 95% CI 11.4%-12.6%;
= 0.78).
Glaucoma follow-up adherence was significantly worse in prisoners compared to a nonincarcerated control population. Further study into causative factors is needed.
Glaucoma follow-up adherence was significantly worse in prisoners compared to a nonincarcerated control population. Further study into causative factors is needed.
To evaluate the outcome of eyes with large Descemet's membrane (DM) perforation during deep anterior lamellar keratoplasty (DALK).
A retrospective, interventional case series of 12 eyes with completed DALK, despite DM perforation larger than 4 mm in its widest dimension. The main outcome measures included graft clarity, endothelial cell density (ECD), corrected distance visual acuity (CDVA), and DM detachment.
The mean age of patients was 26.8 ± 11.4 years. Preoperative pathology included keratoconus (
= 10), macular dystrophy (
= 1), and postmicrobial keratitis corneal scar (
= 1). The average size of DM perforation was 6.5 mm ± 1.3 mm. link2 At the end of the follow-up period (median 15 months, range 6-53 months), the mean CDVA was 0.32 ± 0.09 logMAR and the mean ECD was 1830.8 ± 299.7 cells/mm
. Nine patients (75%) developed DM detachments postoperatively and was managed by intracameral air injection once in six eyes, and twice in three eyes. Other complications included persistent localized stromal edema at the site of DM defect in one eye and Urrets Zavalia syndrome in one eye.
Completing DALK in eyes with large DM perforation provides good visual acuity, endothelial cell count and may be superior to penetrating keratoplasty regarding long-term graft survival if confirmed in future comparative studies.
Completing DALK in eyes with large DM perforation provides good visual acuity, endothelial cell count and may be superior to penetrating keratoplasty regarding long-term graft survival if confirmed in future comparative studies.
To determine economic inequality in visual impairment (VI) and its determinants in the rural population of Iran.
In this population-based, cross-sectional study, 3850 individuals, aged 3-93 years were selected from the north and southwest regions of Iran using multi-staged stratified cluster random sampling. The outcome was VI, measured in 20 feet. Economic status was constructed using principal component analysis on home assets. The concentration index (
) was used to determine inequality, and the gap between low and high economic groups was decomposed to explained and unexplained portions using the Oaxaca-Blinder decomposition method.
Of the 3850 individuals that were invited, 3314 participated in the study. The data of 3095 participants were finally analyzed. link3 The C was -0.248 (95% confidence interval [CI] -0.347 - -0.148), indicating a pro-poor inequality (concentration of VI in low economic group). The prevalence (95% CI) of VI was 1.72% (0.92-2.52) in the high economic group and 10.66% (8.84-12.48) in the low economic group with a gap of 8.