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The reduction in benthic light from natural sediment resuspension events, dredging activities and clouds was quantified over multiple time periods (days to weeks) from a 3-year in-situ field study in the inshore turbid-zone coral communities of the Great Barrier Reef. The results were then used to examine the tolerance levels of three coral species and a sponge to light reduction and associated changes in spectral light quality (in conjunction with elevated sediment concentrations) in a 28-day laboratory-based study. All species survived the exposures but sub-lethal responses involving changes in pigmentation, lipids and lipid ratios were observed. A pocilloporid coral was the most sensitive taxon, with a 28-d EC10 value for bleaching (dissociation of the symbiosis) of 2.7 mol photons m2 d-1. The possibility of such light reduction levels occurring naturally and/or during maintenance dredging activities was then examined using the 3-year in-situ field study as part of a risk assessment.Floating Dangerous Debris For Cetaceans (DDFC) and cetacean abundances were assessed by shipboard visual surveys off continental Portugal. Plastic litter (other than fishing gear) was the most abundant category, corresponding to 56.53% of the total recorded DDFC. Areas of DDFC and cetacean potential overlap suggest that cetaceans are generally exposed to DDFC at different risk levels within the study area. The highest concentration areas of DDFC and cetaceans did not overlap, whereas lower DDFC concentration areas (70% kernel probability contour) overlapped with 45% of the distribution area obtained for cetaceans. Future marine litter management measures (prevention or mitigation) should be focused on the predicted high DDFC-cetacean interaction risk area in the central region of the study. DDFC are representative of the overall floating litter distribution and future floating litter assessments could be based on DDFC categories alone.European oyster (Ostrea edulis) restoration often requires the timely deployment of shell habitat for larval settlement. To inform this increasingly popular process, the present study investigated temporal and spatial abundance patterns of O. edulis larvae in a rare commercial fishery (Loch Ryan, Scotland, UK). Patterns in larval abundance were analysed against variability in temperature, salinity, chlorophyll, oxygen, tidal/moon phase, light, date, and location. 'Temperature sum' (sum total of degrees per day above 7 °C) was the most significant seasonal predictor of larval abundance; with a peak at 617 degree-days. Oyster larval abundance did not significantly vary between oyster bed and non-bed habitats but was significantly higher in the mid and near-surface part of the water column. The findings are discussed in the context of emerging international restoration initiatives and have implications for where habitat restoration would be successful; the prediction of larval connectivity between sites; and a transferable indicator to optimise shell-habitat deployment timing.The present study is aimed at investigation of surface water quality of Gulf of Kachchh (GoK), Gujarat. The main objective of this study was to convert complex dataset of water quality parameters from GoK into comprehensive, simple and interpretable observations. Hence, physico-chemical parameters and nutrients of surface water from GoK were analyzed. Chemometric results indicated that oxygen, salinity, dissolved solids, nutrient and natural conditions were the factors that affected surface water quality. The water quality index was calculated to identify water quality classes to evaluate the spatio-seasonal trend in the study area. The results revealed that water quality was moderate in summer, worst in pre-monsoon and best in post-monsoon. The study also highlighted that Marine National Park (Central GoK) was observed to be comparatively in good condition with abundant marine biodiversity. Thus, the results of chemometric study of water quality parameters can be a valuable tool for government authorities for sustainable development of GoK.Microscopic plastic particles (microplastics) are widespread anthropogenic contaminants that are impacting aquatic ecosystems. Among the five most prevalent types of microplastics (polystyrene, polyamide, polyvinyl chloride, polyethylene, and polypropylene) in aquatic environments, the impact of polystyrene, polyethylene, and polypropylene has drawn more attention due to their high transportability. A lack of reliable inexpensive methods to accurately replicate the realistic microplastic samples extracted from environmental matrixes with the desired size and geometry is one of the main challenges in the design of experiments for systematic studies. In this work, a novel print-and-release technique to prepare colored microplastic (polystyrene) particles with a desired size and shape by using an office-grade laserjet printer is introduced. Microplastics ranging from 125 μm to 500 μm could be prepared with an average dimensional error of less than 5%. Their physical and chemical characteristics were obtained by SEM, FTIR, and XPS analyses.

To determine whether frailty associated factors differ between community dwellers and older adult patients with rheumatoid arthritis (RA).

We used the cross-sectional data for patients with RA from the RA epidemiological quality-of-life study (n=210, mean age 71.8 ± 3.7 years) and community dwellers from the Japan Gerontological Evaluation Study (n=53,255, mean age 71.7 ± 4.0 years). Frailty status was assessed using the Kihon Checklist (KCL), and the primary outcome was frailty (KCL score ≥8 points). Information on predictor variables, including age, sex, marital status, educational level, body mass index (BMI), drinking and smoking status and social participation were obtained from a standardized questionnaire. We employed Poisson regression to calculate the prevalence ratio (PR) of frailty according to its predictors.

We found frailty in 37.6% of the patients with RA and 15.7% of the community dwellers. In the multivariate models, BMI and social participation were independently associated with frailty in patients with RA (BMI <18.5 PR, 1.62; 95% confidence interval [CI] 1.09-2.41. selleck products BMI ≥25.0 PR, 1.81; 95% CI 1.20-2.71. Active social participation PR, 0.61; 95% CI 0.42-0.87) and community dwellers (BMI <18.5 PR, 1.77; 95% CI 1.67-1.88. BMI ≥25.0 PR, 1.27; 95% CI 1.22-1.33. Active social participation PR, 0.46; 95% CI 0.44-0.48). All other predictors were significantly associated with frailty in the community dwellers.

Maintaining appropriate body weight and participating in social activities are important for preventing frailty in patients with RA as well as community dwellers.

Maintaining appropriate body weight and participating in social activities are important for preventing frailty in patients with RA as well as community dwellers.Community science-scientific investigation conducted partly or entirely by non-professional scientists-has many advantages. For example, community science mobilizes large numbers of volunteers who can, at low cost, collect more data than traditional teams of professional scientists. Participation in research can also increase volunteers' knowledge about and appreciation of science. At the same time, there are worries about the quality of data that community science projects produce. Can the work of non-professionals really deliver trustworthy results? Attempts to answer this question generally compare data collected by volunteers to data collected by professional scientists. When volunteer data is more variable or less accurate than professionally collected data, then the community science project is judged to be inferior to traditional science. I argue that this is not the right standard to use when evaluating community science, because it relies on a false assumption about the aims of science. I show that if we adopt the view that science has diverse aims which are often in tension with one another, then we cannot justify holding community science data to an expert accuracy standard. Instead, we should evaluate the quality of community science data based on its adequacy-for-purpose.Chemical synthesis of the tetrasaccharide repeating unit of the O-antigen from E. coli O74 is accomplished by a convergent [2 + 2] block synthesis strategy. The challenging rare D-Fuc3NAc has been prepared using DTBP and TIPST mediated deoxygenation reaction. Other monosaccharide synthons are prepared through rational protecting group manipulations and the stereoselective glycosylations are achieved either by the activation of thioglycoside or glycosyl trichloroacetimidate. The target tetrasaccharide is made in the form of its 2-aminoethyl glycoside to facilitate further glycoconjugate formation without affecting the anomeric stereochemistry.Organization of metabolic processes within the space of a cell is critical for the survival of many organisms. In bacteria, spatial organization is achieved via proteinaceous organelles called bacterial microcompartments, which encapsulate pathway enzymes, substrates, and co-factors to drive the safe and efficient metabolism of niche carbon sources. Microcompartments are self-assembled from shell proteins that encapsulate a core comprising various enzymes. This review discusses how recent advances in understanding microcompartment structure and assembly have informed engineering efforts to repurpose compartments and compartment-based structures for non-native functions. These advances, both in understanding of the native structure and function of compartments, as well as in the engineering of new functions, will pave the way for the use of these structures in bacterial cell factories.

Identifying the possible pattern of help-seeking can explain the gap between care need and actual use of care.

To know the patterns of help-seeking behavior among patients with sexual dysfunction in the context of a developing country.

This was a cross-sectional, qualitative study using criterion sampling among the diagnosed patients of sexual dysfunction attending the psychiatry outpatient department. Based on data saturation, 18 in-depth interviews were done. For method triangulation, 1 key informant interview, 1 informal interview, and 1 focus group discussion were performed. Data were analyzed manually using the thematic analysis method.

Using an interview guideline, face to face interview was performed and the participants reported their pattern of help-seeking regarding their sexual problems.

The majority of the participants were male, within 20-35 years of age range, literate, and from an urban background. Premature ejaculation and female sexual interest/arousal disorder were the most common tern of Help-Seeking Behavior Among Patients With Sexual Dysfunctions Attending in Psychiatry Outpatient Department in a Tertiary Care Hospital of Bangladesh. Sex Med 2021;9100381.

Low intensity extracorporeal shock wave therapy (LIESWT) improves erectile function (EF) in men with vascular erectile dysfunction (ED) but longer-term outcomes remain unknown.

To evaluate the clinical outcomes of LIESWT at a minimum 5-year follow-up.

This is an open-label single-arm prospective study involved men with vascular ED who received LIESWT.

Changes in patient demographics, IIEF-5 and Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) scores, as well as overall satisfaction score (on a 5-point scale) were reviewed at 12, 24, 48, and 60 months after completion of LIESWT. A chi-square contingency analysis was used to examine the relationship between erectile function score and treatment satisfaction, with statistical significance set at 5%.

The mean follow-up period was 69.9 (63-82; median 76) months. The mean IIEF-5 scores for pretreatment and after treatment at 12, 24, 48, and 60 months were 14.8, 17.6, 16.8, 16.5, and 16.5 while the percentages of patients who reported an improvement in IIEF-5 score by 5 points were 60%, 45%, 40%, and 40%; and EDITS scores >50% were recorded in 70%, 55%, 50%, and 48% of patients at 12, 24, 48, and 60 months post-LIESWT.

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