Halseyrichardson6846

Data are stored in a comma separated value format and can be downloaded from the USEPA ScienceHub data repository (https//doi.org/10.23719/1506014).Morphological characterization of chars from coal and bagasse plays an important role in both the burning efficiency and intrinsic reactivity of chars, during a combustion process [1], [2]. Envonalkib price In this work, abundant data on the morphology of chars produced from coal and bagasse blends are presented. Char synthesis was performed varying the temperature (900, 1000 and 1100 °C) and bagasse proportion feeding (0, 25, 50, 75 and 100% w/w) in the pyrolysis reaction. Proximate, ultimate, petrographic and vitrinite reflectance of raw coal and bagasse are presented. Char morphology is classified into three groups -- thin walls, thick walls, and solid particles--, and results are exhibited. The data set is a comprehensive source for advancing in a further understanding of char's morphology from coal-bagasse blends. © 2020 The Authors.Undergraduate subject pools are prevalent across disciplines in the United States. The Health Education Research Experience (HERE) Program was the first known course-based subject pool entirely managed and conducted online for online students enrolled in an introductory health education/health promotion course. The program was conducted within five semesters from Spring 2012 through Summer 2013. The HERE Program encompassed 13 studies embedded in two sections of an undergraduate online course at the University of Florida. The studies were all related to course topics and current research topics in health education/promotion (as identified through the Healthy People 2020 Framework). The topics ranged from the relatively less sensitive health aspects of college life (i.e., technology use) to studies assessing more sensitive health topics (i.e., intimate partner violence and sexual assault). In alignment with a best practice in survey design, the HERE Program's survey instruments included one metadata item embedey Data repository https//data.mendeley.com/datasets/ht9jmd3cdt/2. © 2020 The Author(s).Flatwise tension strength of sandwich structure is important for designing a sandwich construction since it provides failure mechanism and debonding strength between the skin faces and the core, as well as (i) core strength and (ii) face strength of the sandwich structures. The flatwise tension strength is affected by many factores method of core preparation, test environment, testing speed, etc. In this paper, the ambient test temperature was 23 deg C and the humidity was 65%. The testing speed was 0.5 mm/min. Four different core preparations were investigated. ASTM C297 was used as a standard method to get the strength values. Two processes were employed to cure the adhesive during core-to-face bonding. It was found out that cleaning the core with Methyl-ethyl-ketone (MEK) and drying further in an oven gives maximum flatwise tension strength of the sandwich structures, with the value of 5.9 MPa. The data base is important for both the manufacturing and design engineers. For the manufacturing engineers, the data provides a value for process qualification, while for design engineers it gives a maximum allowable strength for designing sandwich construction for tensile loads. © 2019 The Author(s).Background Accumulating evidence points to an association between gut microbial abnormalities and depression disorder. The microbiota-gut-brain axis is an emerging target for treating depression using nutritional strategies, considering the numerous limitations of current pharmacological approaches. Here we studied the effect and probable mechanisms of psychobiotic treatment on depression. Methods Chronically stressed C57BL/6J male mice were administered viable Bifidobacterium breve CCFM1025 for 5 weeks prior to behavioral testing. Brain neurological alterations, serum corticosterone, cytokines levels, fecal microbial composition, and short-chain fatty acid (SCFA) content were measured. In addition, the effect of SCFA on 5-hydroxytryptophan (5-HTP) biosynthesis was investigated in an in vitro model of enterochromaffin cells (RIN14B). Results CCFM1025 treatment significantly reduced depression- and anxiety-like behaviors. The hyperactive hypothalamic-pituitary-adrenal response, as well as inflammation, were also alleviated, possibly via regulating the expression of glucocorticoid receptors (Nr3c1). Moreover, CCFM1025 also down-regulated the pCREB-c-Fos pathway but increased the expression of brain-derived neurotrophic factor (BDNF). Meanwhile, chronic stress-induced gut microbial abnormalities were restored, accompanied by increased SCFA and 5-HTP levels. The intestinal 5-HTP biosynthesis positively correlated with fecal SCFA and Bifidobacterium breve levels. Conclusions In summary, Bifidobacterium breve CCFM1025 showed considerable antidepressant-like and microbiota-regulating effects, which opens avenues for novel therapeutic strategies towards treating depression. © 2020 The Authors.Prenatal stress (PNS) can influence behaviors associated with cognition, reward and emotional regulation, which are controlled by brain areas such as the cortex, hippocampus, hypothalamus, midbrain and cerebellum. Allopregnanolone in these regions modulates behavioral and parasympathetic effects. The current study tested whether exposing pregnant dams to 5 days of resident-intruder stress on prenatal days 15-20 for 10 min altered the levels of allopregnanolone in cortex, hypothalamus, hippocampus, midbrain, and cerebellum of male and female juvenile offspring. In cortex, hypothalamus, and midbrain of male rats exposed to prenatal stress, levels of allopregnanolone were significantly lower compared to all other groups. In the hippocampus and cerebellum, among females exposed to prenatal stress levels were significantly higher compared to all other groups. These differences in allopregnanolone levels varying by prenatal stress, sex and brain regions provide insight in potential mechanism of stress regulation and etiopathophysiology of stress-related disorders. © 2020 The Authors.Pregnane steroids, particularly allopregnanolone (AlloP), are neuroprotective in response to central insult. While unexplored in vivo, AlloP may confer protection against the neurological dysfunction associated with human immunodeficiency virus type 1 (HIV-1). The HIV-1 regulatory protein, trans-activator of transcription (Tat), is neurotoxic and its expression in mice increases anxiety-like behavior; an effect that can be ameliorated by progesterone, but not when 5α-reduction is blocked. Given that Tat's neurotoxic effects involve mitochondrial dysfunction and can be worsened with opioid exposure, we hypothesized that Tat and/or combined morphine would perturb steroidogenesis in mice, promoting neuronal death, and that exogenous AlloP would rescue these effects. Like other models of neural injury, conditionally inducing HIV-1 Tat in transgenic mice significantly increased the central synthesis of pregnenolone and progesterone's 5α-reduced metabolites, including AlloP, while decreasing central deoxycorticosterone (independent of changes in plasma).