Grossarsenault3716

We have developed a portable confocal microscope (PCM) that uses an inexpensive near-infrared LED as the light source. Use of the spatially incoherent light source significantly reduced the speckle contrast. The PCM device was manufactured at the material cost of approximately $5000 and weighed only 1 kg. Lateral and axial resolutions were measured as 1.6 and 6.0 µm, respectively. Preliminary in vivo skin imaging experiment results showed that the PCM device could visualize characteristic cellular features of human skin extending from the stratum corneum to the superficial dermis. Dynamic imaging of blood flow in vivo was also demonstrated. The capability to visualize cellular features up to the superficial dermis is expected to facilitate evaluation and clinical adoption of this low-cost diagnostic imaging tool.We calibrate and test a division-of-focal-plane red-green-blue (RGB) full-Stokes imaging polarimeter in a variety of indoor and outdoor environments. The polarimeter, acting as a polarization camera, utilizes a low dispersion microretarder array on top of a sensor with Bayer filters and wire-grid linear polarizers. We also present the design and fabrication of the microretarder array and the assembly of the camera and validate the performance of the camera by taking multiple RGB full-Stokes images and videos. Our camera has a small form factor due to its single-sensor design and the unique capability to measure the intensity, color, and polarization of an optical field in a single shot.The geometrical propagation of a beam of light is treated in this paper using aberration theory. Stop shifting on the aberration function and on the irradiance function provides insight into how the geometrical field changes as it propagates in free space. The formulae discussed in this paper give as a function of the field and aperture of an optical system, and to the sixth order of approximation, the wavefront deformation and, to the fourth order, the irradiance at the exit pupil plane of the system. The use of the formulae is illustrated with a lens design for uniform illumination that is nearly insensitive to the location of the illuminated surface.Relative illumination is affected by image distortion, pupil coma, and pupil magnification. Image and pupil aberrations have a known relationship that also can be written in terms of pupil magnification. see more Pupil coma is the stretching or compression of the pupil along the field axis, which directly affects relative illumination. Front-stopped designs have pupil aberrations on the exit pupil while rear-stopped systems have pupil aberrations on the entrance pupil. Of the primary pupil aberrations, pupil coma can have the largest effect on the relative illumination in optical designs with significant image distortion (ex fisheye lens). The Lagrange invariant holds for systems with image distortion using a paraxial approximation of pupil coma. Relative illumination can be written in terms of % distortion, pupil magnification, and object-space field angle.In this paper a photovoltaic system is proposed that achieves high energy yield by integrating bifacial silicon cells into a spectrum-splitting module. Spectrum splitting is accomplished using volume holographic optical elements to spectrally divide sunlight onto an array of photovoltaic cells with different bandgap energies. Light that is reflected from the ground surface onto the rear side of the module is converted by the bifacial silicon cells. The energy yield of the system is optimized by tuning the volume holographic element parameters, such as film thickness, index modulation, and construction point source positions. An example is presented for utility-scale illumination parameters in Tucson, Arizona, that attains an energy yield of $1010\frac kw\cdot hr yr\cdot m^2$1010kw⋅hryr⋅m2, which is 32.8% of the incident solar insolation.Pancreatic cancer is a common cancer with poor odds of survival for the patient, with surgical resection offering the only hope of cure. Current surgical practice is time-consuming and, due to time constraints, does not sample the whole cut surface sufficiently to check for remaining cancer. Although microscopy with hematoxylin and eosin (H&E) stain is the gold standard for microscopic evaluation, multiphoton microscopy (MPM) has emerged as an alternative tool for imaging tissue architecture and cellular morphology without labels. We explored the use of multimodal MPM for the label-free identification of normal and cancerous tissue of the pancreas in a mouse model by comparing the images to H&E microscopy. Our early studies indicate that MPM using second-harmonic generation, third-harmonic generation, and multiphoton excitation of endogenous fluorescent proteins can each contribute to the label-free analysis of the pancreatic surgical margin.Fano resonance is a pervasive resonance phenomenon which can be applied to high sensitivity sensing, perfect absorption, electromagnetic-induced transparency, and slow-light photonic devices. In this paper, we propose a metal-insulator-metal (MIM) waveguide structure consisting of a D-shaped cavity and a bus waveguide with a silver-air-silver barrier. The Fano resonance can be achieved by the interaction between the D-shaped cavity and the bus waveguide. The finite element method is used to analyze the transmission characteristics and magnetic-field distributions of the structure in detail. Simulation results show the Fano resonance can be adjusted by altering the geometric parameters of the MIM waveguide structure or the refractive index of the D-shaped cavity. The maximum refractive index sensitivity of the structure can reach up to 1510 nm/RIU, and there is a good linear relationship between resonance wavelength and refractive index. Since it has good sensitivity and tunability, the MIM waveguide structure can be used in bio-sensing, such as human hemoglobin detection. We show its applicability for the detection of three different human blood groups as well.Electronic distance meters (EDMs) are widely used in different applications, such as surveying and civil engineering. In order to calibrate an EDM, different techniques can be used, including displacement interferometers and reference baselines. In this paper, an indoor baseline is designed and then accurately measured using femtosecond laser pulses from an optical frequency comb to be used for EDM calibration. The baseline consists of 13 fixed bases that cover 58 m distance. In order to accurately measure the distances between the bases, autocorrelation between femtosecond laser pulses is employed. The measurement shows a maximum precision of 14 µm over the 13 bases. Although this deviation is dominated mainly by the placement of the target mirror, the system capability is much more sufficient to safely calibrate the best available commercial EDM. The stability of the baseline is also investigated by measuring the interbase distances over long periods of time.