Graukristensen9585

Our findings show that patients with HNC living in low socioeconomic areas had worse OS.

The aim of this study was to clarify the physical and mental burden of the COIVD-19 pandemic on obstetricians and gynecologists in Japan and to identify factors that increase the burden of their psychological stress.

A web-based questionnaire was sent to obstetricians and gynecologists in Japan via email and social media to collect voluntary responses. This survey was conducted from September 1 to 30, 2020.

A total of 852 valid responses were included in the analysis; 76% (644) of the physicians felt that the COVID-19 pandemic caused them physical and mental stress equal to or greater than the most severe disaster they had ever experienced. Physicians who reported high mental and physical stress were more likely to be in areas with high numbers of infected patients (odds ratio (OR) 1.571, p=0.012). Physicians experienced great stress to the point of wearing heavy personal protective equipment during routine vaginal deliveries by mothers with no COVID-19 symptoms. This trend was markedly pronounced for physicians working in regions with fewer cases of COVID-19 infection.

Obstetricians and gynecologists who reported high mental and physical stress were more likely to be in areas with high numbers of infected patients. One potential reason for this may be that they were required to wear more personal protective equipment than necessary. Infection control methods that ensure the safety of obstetricians and gynecologists while not causing unnecessary physical or psychological stress are needed.

Obstetricians and gynecologists who reported high mental and physical stress were more likely to be in areas with high numbers of infected patients. One potential reason for this may be that they were required to wear more personal protective equipment than necessary. Infection control methods that ensure the safety of obstetricians and gynecologists while not causing unnecessary physical or psychological stress are needed.

Manual brain extraction from magnetic resonance (MR) images is time-consuming and prone to intra- and inter-rater variability. Several automated approaches have been developed to alleviate these constraints, including deep learning pipelines. However, these methods tend to reduce their performance in unseen magnetic resonance imaging (MRI) scanner vendors and different imaging protocols.

To present and evaluate for clinical use PARIETAL, a pre-trained deep learning brain extraction method. We compare its reproducibility in a scan/rescan analysis and its robustness among scanners of different manufacturers.

Retrospective.

Twenty-one subjects (12 women) with age range 22-48 years acquired using three different MRI scanner machines including scan/rescan in each of them.

T1-weighted images acquired in a 3-T Siemens with magnetization prepared rapid gradient-echo sequence and two 1.5 T scanners, Philips and GE, with spin-echo and spoiled gradient-recalled (SPGR) sequences, respectively.

Analysis of thee-tuning it again. PARIETAL is publicly available.

2 TECHNICAL EFFICACY STAGE 2.

2 TECHNICAL EFFICACY STAGE 2.

Exposure to repetitive head impacts (RHI) is associated with an increased risk of later-life neurobehavioral dysregulation and neurodegenerative disease. The underlying pathomechanisms are largely unknown.

To investigate whether RHI exposure is associated with later-life corpus callosum (CC) microstructure and whether CC microstructure is associated with plasma total tau and neuropsychological/neuropsychiatric functioning.

Retrospective cohort study.

Seventy-five former professional American football players (age 55.2 ± 8.0 years) with cognitive, behavioral, and mood symptoms.

Diffusion-weighted echo-planar MRI at 3 T.

Subjects underwent diffusion MRI, venous puncture, neuropsychological testing, and completed self-report measures of neurobehavioral dysregulation. RHI exposure was assessed using the Cumulative Head Impact Index (CHII). Diffusion MRI measures of CC microstructure (i.e., free-water corrected fractional anisotropy (FA), trace, radial diffusivity (RD), and axial diffusivity (AD)) wereT-B (trace, r= 0.31; RD, r= 0.34). Higher FA and AD of CC2 were associated with better performance (P< 0.05) in TMT-A (FA, r= 0.36; AD, r= 0.28), TMT-B (FA, r= 0.36; AD, r= 0.27), COWAT (FA, r= 0.36; AD, r= 0.32), and BRI (AD, r= 0.29).

These results suggest an association among RHI exposure, CC microstructure, plasma total tau, and clinical functioning in former professional American football players.

3 Technical Efficacy Stage 1.

3 Technical Efficacy Stage 1.Insomnia has been shown to negatively affect one's cognitive functioning. While there has been some evidence suggesting sleep disruption in relation to impaired inhibitory control, a major component of executive function, little is known about the underlying neural processing in insomnia. The current study aimed to examine the differences in the behavioral responses and electroencephalography (EEG) correlates of inhibitory control between youths with insomnia and healthy sleepers. Twenty-eight participants with insomnia disorder and 31 healthy sleeper controls aged between 15 and 25 completed the study. see more Electroencephalographic activity was recorded during the Cued Go/NoGo (CGNG) task, a task assessing inhibitory control. Although insomnia group exhibited comparable behavioral performance to the healthy sleeper group, they showed impaired attention preparation, as displayed by a smaller contingent negative variation (CNV) component (F = 4.10, p = 0.048) after cue onset; and demonstrated impaired inhibitory control, as evidenced by smaller N2 and theta power on 200-350 ms (MANCOVA multivariate Group effect, F = 5.85, p less then 0.001). The results suggested that youths with insomnia demonstrated altered brain activity during inhibitory control, despite their comparable behavioral performance. Given that impaired inhibitory control is often implicated in psychopathology, future studies with a longitudinal design are needed to further explore the long-term impacts and trajectory of altered inhibitory control in youths with insomnia.