Grantcheng4103

Using FPG alone as the criteria, the sensitivity was 43.42%, 81.58% and 68.42%, where as A1C alone as the criteria, the sensitivity was 77.63%, 100% and 98.68% baseline, 3 months and 6 months intervals respectively whereas specificity was 100%. Among AGT and NGT, dyslipidemia was found to be statistically significant among AGT group (p=0.01). Mean Serum triglycerides (165.11, p <0.001) and LDL cholesterol (99.65, p<0.001) in AGT group.

There is increased prevalence of prediabetes and newly diagnosed DM in patients with TB and they are more to develop dyslipidemia.

There is increased prevalence of prediabetes and newly diagnosed DM in patients with TB and they are more to develop dyslipidemia.Diabetes mellitus is a major global health problem, increasingly affecting the population across the world. Diabetic patients have an increased risk of developing micro and macro vascular diseases, and platelets may be involved as a causative agent with respect to altered platelet morphology and function. There are studies evaluating the association between Mean Platelet Volume (MPV) and HbA1c and its role in predicting glycaemic control with conflicting results. Thus the present study was conducted to assess the relationship between HbA1c levels and platelet activity (MPV), determine the association among MPV, glycemic control, and diabetic vascular complications and to evaluate the influence of improved glycemic control on MPV in type 2 diabetic patients.

This was a hospital based observational comparative study on 100 cases of diabetes mellitus divided in 2 groups i.e Group A (HbA1c <7) and Group B (HbA1c >7) and 50 healthy controls in Group C in hospital wards and OPD of SMS Medical College MPV.Air pollution exposure have been shown to adversely impact health through a number of biological pathways, and is also associated with glucose metabolism. There are few studies that evaluated the associations between air pollution and fasting blood sugar and HbA1C levels. But no such study occurred in Indian population. Hence to address this knowledge gap, we investigated the associations between air borne fine particulate matter (PM10, PM2.5), nitrogen di-oxide and glucose metabolism in a tertiary care center in north western rajasthan.

We performed cross-sectional analysis in 3457 participants between 30 to 70 years of age group from five different urban and rural areas of Bikaner district. Air pollution concentration of multiple air pollutants (PM10, PM2.5andNitogen dioxide) were estimated by ambient air quality standard method by respiratory dust sampler. Diabetes was defined based on self reported diagnosis, medication prescription, oral glucose tolerance test and HbA1C. Tetrahydropiperine We adjusted for potential confou%CI -0.042,-0.015) and by adding NO2 (odd ratio 0.140,95% CI 0.104,0.175).

long term air pollution exposure was associated with impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and prevalence of diabetes mellitus (DM). This study can be used as a good evidence that air pollution is an important and manageable risk factor for diabetes hence awareness about air pollution in the society and at government level is much needed.

long term air pollution exposure was associated with impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and prevalence of diabetes mellitus (DM). This study can be used as a good evidence that air pollution is an important and manageable risk factor for diabetes hence awareness about air pollution in the society and at government level is much needed.Hypothyroidism is a common disease with a prevalence rate of 11% in India. It effects all organ systems in the body. Patients with hypothyroidism frequently have symptoms of fatigue and exercise intolerance. These symptoms could rise from a reduced pulmonary reserve, cardiac reserve or reduced muscle strength or increased muscle fatigue. There are very few studies done in the past to evaluate effect of thyroid disorder on pulmonary function. So, this study is focused on estimating effects of hypothyroidism on pulmonary function of affected individual Material and Aim To study pulmonary functions using spirometry in hypothyroidism patients.

To assess correlation of pulmonary functions with age of patient, BMI values, duration of hypothyroidism and Serum TSH levels.

After getting approval from institutional ethics committee, total of 50 patients with hypothyroidism were studied for their Pulmonary function using spirometry. Adults who are below the age of 80 years and who gave valid, informed consent with hiduration of hypothyroidism and BMI.

Findings of this study are consistent with restrictive type of lung disease in hypothyroidism patients. Hypothyroidism compromises the pulmonary function of affected individuals to variable degree depending on duration of disease and higher levels of TSH and BMI. Therefore, all hypothyroid patients should be screened for abnormalities of pulmonary functions. All patients with impaired pulmonary functions must be screened for thyroid function tests to detect and prevent adverse outcomes.

Findings of this study are consistent with restrictive type of lung disease in hypothyroidism patients. Hypothyroidism compromises the pulmonary function of affected individuals to variable degree depending on duration of disease and higher levels of TSH and BMI. Therefore, all hypothyroid patients should be screened for abnormalities of pulmonary functions. All patients with impaired pulmonary functions must be screened for thyroid function tests to detect and prevent adverse outcomes.Polycystic Ovarian Syndrome remains as the most common endocrine disorder among females and are at increased risk of developing early onset atherosclerosis.1Studies have also demonstrated increased Carotid Intima- Media Thickness (CIMT), which is a predictor of coronary and cerebrovascular events among relatively younger women. Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease which is associated with significant morbidity and mortality and occur in higher prevalence in Polycystic ovarian syndrome patients. This study aims to estimate cardiovascular morbidity in PCOS patients with or without Non Alcoholic Fatty Liver Disease.

22 Polycystic Ovarian Syndrome patients already diagnosed by Rotterdam's criteria were included in this study.Abdominal Ultrasonography screening was used to identify patients with Non-Alcoholic Fatty Liver Disease and patients without Non Alcoholic Fatty Liver Disease. Demographic and anthropometric data was noted in both groups. Cardiovascular morbiditAlcoholic Fatty Liver Disease with R2=0.59. There was no significant association between e/a ratio and TG/HDL ratio between NAFLD and non NAFLD. There was no significant association between Body mass index and carotid intima media thicknesss between NAFLD and Non NAFLD.

There is a significant association of cardiovascular morbidity in Polycystic ovarian syndrome with Non-alcoholic Fatty Liver Disease.

There is a significant association of cardiovascular morbidity in Polycystic ovarian syndrome with Non-alcoholic Fatty Liver Disease.Male reproductive functions are governed by hypothalamic pituitary testicular axis. If any component of this axis malfunctions, then hypogonadism will develop which is characterized by ill-defined secondary sexual features and low serum testosterone. The common patterns seen are primary and secondary testicular failure in the young; and late onset hypogonadism in the elderly. All such cases can be virilized and managed by androgen supplementation. Spermatogenesis can be induced by use of appropriate gonadotropins in selected cases. The aim of the study was to find out the pattern, management and outcome of male hypogonadism.

It was a prospective questionnaire based observational study, carried out on infertile hypogonadic males, attending medicine outdoor at medical college hospital from January 2015 to December 2020. There were 50 males with hypogonadic features, cases of late onset of hypogonadism were excluded. Sexual maturity rating, semen analysis, serum testosterone and FSH level were estimated in all re common than secondary testicular failure. Both pattern of hypogonadism should receive lifelong androgen replacement therapy; otherwise, they will be a basket of multiple systemic disorders. Presently testosterone undecanoate once in every three months is the agent of choice.

The study brings out that primary testicular failure is more common than secondary testicular failure. Both pattern of hypogonadism should receive lifelong androgen replacement therapy; otherwise, they will be a basket of multiple systemic disorders. Presently testosterone undecanoate once in every three months is the agent of choice.The complex relationship between BMI, thyroid and its effects on OSA raises a question on how patients with suspected OSA should be evaluated. Some studies have described an association between thyroid disorders and OSA. Whether this is a direct effect of thyroid disorders, or it is indirectly related to BMI values is an important point to ponder. The aim of this study was to estimate the prevalence of thyroid disorders in relation to BMI in newly diagnosed patients with OSA (AHI > 5/h on diagnostic Polysomnography) at sleep lab of our tertiary care centre. In addition, we compared baseline characteristics of OSA patients with thyroid parameters.

In this hospital based observational study, recently diagnosed OSA on the basis of PSG showing AHI > 5/ h according to the AASM 2012 scoring rules and age more than 18 years were recruited from OPD and in-patients of SMS Medical College Jaipur. Patients on previous CPAP treatment, mixed or predominantly central sleep apnea, known diabetics and language bar function tests and BMI.

The prevalence of hypothyroidism was common among patients with OSA and the severity of OSA correlated with thyroid function tests and BMI.The low T3 syndrome, the most common type of Sick Euthyroid syndrome, once believed to be a beneficial adaptive mechanism under conditions of stress, has emerged as a strong prognostic determinant in chronic systolic heart failure. Sick Euthyroid Syndrome is frequently observed in Chronic Heart Failure, Acute Myocardial Infarction. Acute myocardial infarction (AMI) may be associated with a number of endocrine alterations, including those of the SES which reflect the acute hormone response to stress and trauma. It is known from several studies that several cytokines can be found elevated in patients with cardiac ischemia or AMI. From in vitro studies it is of particular interest that ischemic myocytes produce cytokines such as interleukin-6 (IL-6) and its synthesis is accelerated by reperfusion. Interleukin-6 seemed to be an important cytokine produced by the injured myocytes in patients with AMI, and strong negative correlation between serum IL-6 concentration and left ventricular ejection fraction (LVEF) haspg/ml for the patients who improved and 1.61pg/ml for the patient who expired, indicating statistical significance. Mean fT4 and TSH was not significant across those who improved or expired. However high rT3 value was associated with the worst outcome.

Prevalence of SES is commom in patient with ACS. SES is a strong prognostic indicationin ACS. It is frequently observed in chronic heart failure, acte MI and is related to increased mortality.

Prevalence of SES is commom in patient with ACS. SES is a strong prognostic indicationin ACS. It is frequently observed in chronic heart failure, acte MI and is related to increased mortality.