Goodewaller7440
In contrast to the broad evidence for the effectiveness of multidisciplinary biopsychosocial rehabilitation (MBR) in chronic low back pain (CLBP) patients of working age, little is known about the benefit in patients aged ≥ 65 years.
To quantify the short-term and 12-month effects of a 3-week CLBP specific MBR program in patients ≥ 65 years of age; to compare the effects in patients ≥ 65 years of age to the effects in younger patients.
Observational prospective cohort study.
Outpatient clinic at a tertiary physical medicine and rehabilitation centre.
Consecutive patients with CLBP who participated in a CLBP a specific MBR program.
The 3-week MBR program included 44 hours of treatment. The primary outcomes pain and disability were measured by the North American Spine Society Questionnaire (NASS). Secondary outcome measures were the Short-Form 36 (SF-36) and the numerical rating scale for pain. Effects were quantified using effect sizes (ES).
From 203 included patients, 104 patients older than 65 t of MBR in the growing population of CLBP patients older than 65 years of age.
The findings support the concept of MBR in the growing population of CLBP patients older than 65 years of age.
Current pectus excavatum management includes a Computed Tomography scan to evaluate the Correction Index, whose superiority to the Haller Index in terms of specificity and sensibility is still under debate. Furthermore, several studies report interchangeability between the Haller Index as measured by Computed Tomography and as measured by X-radiograph; however it is not clear whether this correlation also exists for the Correction Index. The aim of our study was to evaluate the correlation between measurements of the Haller Index and the Correction Index obtained by Computed Tomography and by X-radiograph.
This prospective study included 31 patients with Pectus Excavatum (who underwent preoperative chest Computed Tomography and X-radiograph) and a control group of 31 patients (who presented no chest deformity and underwent the same exams for other unrelated causes). We measured Haller Index and Correction Index on both exams for both groups. To demonstrate any correlation between Computed Tomography scans and X-radiographs for the two indexes, the Pearson R correlation test, Bland-Altman analysis and Anova Nested test were performed.
Pearson's coefficient (0.829 with p < 0.0001) and Anova Nested test showed a significant correlation and similar results between the Haller Index and the Correction Index on Computed Tomography and on X-radiograph.
Significant correlation and similar results are shown in our study in the measurement of CI and HI on Computed Tomography and X-radiograph. Further studies including a larger number of patients may be warranted.
Significant correlation and similar results are shown in our study in the measurement of CI and HI on Computed Tomography and X-radiograph. Further studies including a larger number of patients may be warranted.
Mortality of newborns with Hypoplastic Left Heart Syndrome (HLHS) is mainly concentrated after Norwood procedure (NP) stage 1 palliation (S1P) and between S1P and stage 2 palliation (S2P). Standardized management of these patients may help to control hospital mortality. Aim of the study was to evaluate the impact on hospital mortality of a standardized perioperative management (SPM) for newborns requiring S1P in a low volume center for NP.
A consecutive series of patients undergoing S1P from January 1, 2002 to December 31, 2006 were retrospectively compared, by a "before and after" design, with those receiving a SPM (i.e. use of selective cerebral perfusion, near infrared spectroscopy, delayed sternal closure, modified ultrafiltration) from January 1, 2007 to December 31, 2018. Demographic, intraoperative and postoperative characteristics were collected. https://www.selleckchem.com/products/ccs-1477-cbp-in-1-.html Univariate and multivariate analyses assessed differences before and after SPM.
91 newborns underwent S1P in the considered period; of 74 eligible patients, 25 didn't receive SPM, while 49 received SPM. Hospital mortality after S1P was 31% (CI 21-44%). The introduction of a SPM didn't affect hospital mortality both at the univariate (28% vs 29%, p = 0,959) and at the multivariate analysis (HR 1.85, p=0.62). Mortality was 12% (CI 6-25%) between hospital discharge after S1P and S2P and 8% (CI 3-22%) between S2P and S3P.
The use of a SPM for HLHS newborns requiring S1P was not effective in reducing hospital mortality in a low volume center. We suggest a collaboration between Italian Pediatric Cardiac Centers to manage HLHS patients.
The use of a SPM for HLHS newborns requiring S1P was not effective in reducing hospital mortality in a low volume center. We suggest a collaboration between Italian Pediatric Cardiac Centers to manage HLHS patients.
An appropriate size of device for patent ductus arteriosus (PDA) could be chosen by a stretched PDA size. We propose prediction of stretched size from intact PDA size.
A total of 361 patients was enrolled. Intact size was measured on angiography before closure, and stretched size was the narrowest diameter immediately after device implantation.
The median patient age was 2.8 years. Intact diameter and stretched diameter were 3.6 ± 1.4 mm and 5.1 ± 1.3 mm. The difference and difference ratio were 1.5 ± 0.8 mm and 51.3 ± 38.1% and had negative linear correlations with age (P<0.001). Patients were divided into four groups; < 2 years old (159), 2-15 years old (68), 15 - 40 years old (72), and ≥ 40 years old (62). Among groups, difference and difference ratio were significantly different. Stretched diameter was inferred by the following formulas stretched diameter = 0.660ⅹintact diameter + 2.791 (<2 years old); = 0.971ⅹintact diameter +0.058ⅹage +1.131 (2-15 years old); = 0.790ⅹintact diameter +2.263 (15 - 40 years old); and = 0.837ⅹintact diameter +1.353ⅹBSA -0.096 (≥40 years old).
Stretched PDA diameter can be predicted from intact diameter and might be helpful for safe PDA closure especially in small infants.
Stretched PDA diameter can be predicted from intact diameter and might be helpful for safe PDA closure especially in small infants.