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Therefore, neutral diclofenac-induced changes in the structural properties of the external phospholipid layers of the gastric mucosa may constitute an additional toxicity mechanism of this worldwide-used drug, which shall be considered for the development of safer therapeutic strategies. SIGNIFICANCE STATEMENT Neutral or anionic diclofenac exerted distinct alterations in phosphatidylcholine bilayers, which are used in this work as models for the protective phospholipid layers of the gastric mucosa. Remarkable changes were induced by neutral diclofenac in the structural properties of the phospholipid bilayer, suggesting that both ionized and neutral states of nonsteroidal anti-inflammatory drugs must be considered to clarify their mechanisms of toxicity and to ultimately develop safer anti-inflammatory drugs. Copyright © 2020 by The Author(s).Climate change is a serious threat to human health. Nurses recognize vulnerable populations are disproportionately affected by the consequences from climate change, especially the elderly, pregnant women, and children. Children with asthma and chronic health conditions are at the greatest risk for negative health outcomes and are the most important reason for climate advocacy. This descriptive correlational study seeks to assess the knowledge, attitudes, and behaviors of school nurses related to the health impacts of climate change. School nurses are in a unique position to address the health impacts of climate change and become fierce advocates of climate justice because of population they serve. School-age and adolescent students are particularly vulnerable to the consequences climate change, which include poor air quality, increasing temperatures, and increasing pollen counts. School nurses were invited to participate in the study via email and provided information about the Nurses Climate Change Challenge. It was the goal of the study to assess these domains in school nurses' and later develop continuing education to support the care and advocacy of students. The results suggest more continuing education on climate change and climate conscious care is needed for school nurses. The current challenge is not only to be more prepared to treat a greater number of illnesses induced by climate change, it is also to maintain expertise and adapt to a changing environment. Nurses must address the impact of climate change on a local level by making changes in practice and engaging in research so that they are prepared with the knowledge, and skills to offer expertise in environmental health and the care of school-age populations. © Copyright 2020 Springer Publishing Company, LLC.Healthcare contributes significant pollution to the natural environment. Nurses are obligated by professional commitment, to avoid causing harm in their care processes and decisions, including environmental harm. Nurse awareness of healthcare-generated pollution is growing but nurses may lack an understanding of how nursing contributes specifically to this pollution and what nurses can do within their scope and span to address it. This chapter introduces the concept "Nurse-Sensitive Environmental Indicators" as a proposal to identify, measure, and reduce the unintended harm of nursing practice that contributes to healthcare-generated pollution. It discusses the environmental problem, environmental health, and healthcare. The chapter explains what environmental stewardship has to do with nursing and describes nurse sensitive indicators. As has been the case with other quality outcomes measures, identifying agreed-upon environmental outcomes measures may give the nursing profession tools to measure and then address environmental impacts arising from nursing practice. © Copyright 2020 Springer Publishing Company, LLC.The purpose of this chapter is to report the findings gathered in an author-designed survey of new nurse graduates in Connecticut of their confidence in the application of environmental health in their nursing practice. An invitation to the survey was included in newsletters of Connecticut Nurses Association sent to all practicing nurses in Connecticut. New nurse graduates' confidence level regarding incorporation of environmental health vary substantially among the aspects of environmental health and this confidence decreases as they progress through the steps of the nursing process. CC-90011 cell line © Copyright 2020 Springer Publishing Company, LLC.This chapter outlines the guiding theoretical framework of EcoJustice Education (EJE), research questions, semistructured interviews with nursing scholars that begin to question the perceptions that lead us to the crisis and recommendations of how sustainability efforts can help to address the vital relationality of human beings to water. It highlights the profession of nursing education in order for nurses to understand their roles within the context of the crises. The EJE theoretical framework will help nurse educators reimagine a new understanding and a powerful discovery that includes the awareness of a broad set of historically constructed and politically motivated power knowledge relations in nursing. The chapter provides examples and discussions of four dominant discourses predominant within the Flint Water Crisis and Detroit Water Shutoffs anthropocentrism, ethnocentrism, individualism, and mechanism. These discourses are related to nursing education to further explain how they are pervaded in nursing. © Copyright 2020 Springer Publishing Company, LLC.The health implications of food and agriculture production are not generally part of the nursing curriculum and yet nurses understand that vulnerable populations, such as farmworkers, may need special attention in terms of health education, disease prevention, and access to mental health and healthcare services. Nurses also learn about the social determinants of health and increasingly are applying this knowledge to health and wellness in their communities. This article will consider the health impacts of the social determinants and both environmental and occupational exposures experienced by farmworkers and the associated implications for the nursing profession. As health professionals one can help to give voice to this often-voiceless population. Working with farmworkers in partnership is key and working with the Migrant Clinicians Network and other advocacy organizations on state and federal policies that will improve working and living conditions for farmworkers and their families is crucial. © Copyright 2020 Springer Publishing Company, LLC.

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