Glennlynge4648

To analyze the influence of a cilioretinal artery on macular and peripapillary vessel density in healthy eyes as measured using optical coherence tomography angiography (OCTA).

83 eyes of 83 patients were included in this study. Optical coherence tomography angiography was performed using the RTVue XR Avanti with AngioVue (Optovue Inc).The macula was imaged with a 3 × 3-mm scan, whereas for the optic nerve head (ONH) a 4.5 × 4.5-mm scan was taken. OCTA images of the ONH were screened for the presence of a CRA.

In 31 eyes, a CRA was detected (37,3%). The vessel density (VD) in eyes with a CRA was significantly lower within the ONH (P=0.005), but higher in the peripapillary capillary network (P<0.001) and (whole en-face) macular superficial capillary plexus (P=0.025), when compared to eyes with no CRA.

Our findings reveal that in eyes with a CRA, the VD in the peripapillary and macular SCP are increased, while the ONH perfusion (as indicated by VD in the inside disc region) is decreased. This has to be considered when analyzing quantitative OCTA parameters in scientific and clinical applications.

Our findings reveal that in eyes with a CRA, the VD in the peripapillary and macular SCP are increased, while the ONH perfusion (as indicated by VD in the inside disc region) is decreased. This has to be considered when analyzing quantitative OCTA parameters in scientific and clinical applications.

To review the autologous retinal transplantation (ART) surgical technique, indications, rationale, and current outcomes of data published to date.

Review of surgical technique, pre- and postoperative best-corrected visual acuity (BCVA), and macular hole (MH) closure rate in studies with at least 5 eyes.

The weighted average MH closure rate is 88% with a MH closure rate ranging from 66.7-100%. The weighted average BCVA improved from mean logMAR of 1.35 (Snellen equivalent of 20/450) preoperatively to mean logMAR 1.02 (Snellen equivalent of 20/210) postoperatively. From the largest ART case series, 37% of patients gained 3 or more lines of visual acuity after ART for primary or refractory MHs and 74% gained 3 or more lines of visual acuity after ART for MH-retinal detachments. Functional improvement including negative Watzke-Allen sign and conversion from positive to negative scotoma was reported in large case series.

ART is a promising technique for closure of large and refractory MHs otherwise difficult to repair with conventional techniques. This technique may allow for replacement of neural tissue in the macula through cell rehabilitation and regeneration through presumed ectopic synaptogenesis, retinal progenitor cell differentiation and integration, and/or retinal progenitor cell material transfer to host neurons.

ART is a promising technique for closure of large and refractory MHs otherwise difficult to repair with conventional techniques. This technique may allow for replacement of neural tissue in the macula through cell rehabilitation and regeneration through presumed ectopic synaptogenesis, retinal progenitor cell differentiation and integration, and/or retinal progenitor cell material transfer to host neurons.

To compare posterior vitreous detachment (PVD) identification rate between clinical examination vs. spectral domain optical coherence tomography (SD-OCT) in patients with retinal detachment (RD).

Data from the Primary Retinal detachment Outcomes (PRO) study was utilized for this retrospective cross-sectional study of 506 patients. SD-OCT scans were reviewed to detect separation of the posterior hyaloid face from the retina and the optic nerve on all 31 raster cuts of a 30 x 30 scan. Statistical analysis was performed to compare SD-OCT identified PVD with PVD identified on slit lamp biomicroscopy.

There was a significant difference in rate of PVD identification by clinical examination vs. SD-OCT in patients with RD. Clinical exam identified 51.58% of patients with PVD while SD-OCT showed 78.42%. In patients with macula on RD, 61.68% were found to have PVD on clinical examination vs. 83.90% by imaging. SD-OCT identified larger number of PVD in macula off RD patients compared to clinical examination, 46.28% vs 75.43% respectively. There was low agreement between the two methods (Kappa score = 0.137). There was a significant difference in surgical procedure type chosen in those with vs without a PVD.

Knowledge about the posterior hyaloid anatomy is important before undergoing RD repair. SD-OCT can better identify PVD than clinical examination in patients with RD.

Knowledge about the posterior hyaloid anatomy is important before undergoing RD repair. SD-OCT can better identify PVD than clinical examination in patients with RD.

Pain is a complex experience that involves sensation, emotion, and cognition. The subjectivity of the traditional pain measurement tools has expedited the interest in developing neuroimaging techniques to monitor pain objectively. Among noninvasive neuroimaging techniques, functional near-infrared spectroscopy (fNIRS) has balanced spatial and temporal resolution; yet, it is portable, quiet, and cost-effective. These features enable fNIRS to image the cortical mechanisms of pain in a clinical environment. In this article, we evaluated pain neuroimaging studies that used the fNIRS technique in the past decade. Starting from the experimental design, we reviewed the regions of interest, probe localization, data processing, and primary findings of these existing fNIRS studies. We also discussed the fNIRS imaging's potential as a brain surveillance technique for pain, in combination with artificial intelligence and extended reality techniques. We concluded that fNIRS is a brain imaging technique with great potentded that fNIRS is a brain imaging technique with great potential for objective pain assessment in the clinical environment.

Chronic pain is associated with reduced quality of life, increased medical expenditures, and significant economic costs. Chronic pain is among the most common chronic conditions in the United States, although estimates vary widely regarding its precise prevalence. Understanding the scope of the problem using the most contemporaneous data is therefore an important goal. This study sought to determine the prevalence of chronic pain and its impacts among adults in the United States using the National Health Interview Survey, a household-based annual survey of self-reported health status of U.S. adults that can be used to generate national-level estimates. Using a chronic pain module introduced in the 2019 edition of National Health Interview Survey, we found that 50.2 million adults (20.5%) reported pain on most days or every day. The most common pain locations were back pain and hip, knee, or foot pain. KU-60019 manufacturer The most commonly used management strategies for chronic pain were physical therapy and massage. Respondents with chronic pain reported limitations in daily functioning, including social activities and activities of daily living.