Glennbentley8727

Além disso, observamos que o grupo PCOS apresentou maior modulação cardíaca autonômica simpática nos momentos supino 2, inclinado 1 e supino 3 em comparação aos controles. CONCLUSãO  Mulheres com SOP apresentaram modulação cardíaca simpática autonômica mais alta mesmo após um segundo teste de inclinação. Nenhuma adaptação a esse teste provocativo foi observada. A análise espectral foi mais sensível para identificar diferenças entre os grupos do que a análise simbólica.in English, Portuguese OBJETIVO  Avaliar o impacto da presença de critérios de morbidade materna grave e potencial evento adverso materno associados a distúrbios hipertensivos nos desfechos maternos e perinatais em uma maternidade escola. MéTODOS  Trata-se de uma subanálise de um estudo maior, envolvendo 27 centros, que estimou a prevalência de morbidade materna grave e potencial evento adverso no Brasil. selleck chemicals llc Realizou-se um estudo analítico e transversal, com abordagem quantitativa, envolvendo 928 mulheres atendidas na Maternidade Escola Assis Chateaubriand (MEAC), na Universidade Federal do Ceará (UFC), no período de julho de 2009 a junho de 2010, diagnosticadas com potencial evento adverso de acordo com os critérios da Organização Mundial da Saúde (OMS). A amostra foi dividida em dois grupos pacientes com (n = 827) e sem hipertensão (n = 101). Os resultados foram considerados estatisticamente significativos quando p  less then  0,05. O teste do Qui-quadrado de Pearson e o teste exato de Fisher foram usados para as variáveis categóricas, e o teste U de Mann-Whitney, para as variáveis contínuas. RESULTADOS  Foram identificados 51 participantes com critérios de potencial evento adverso materno, sendo 36 mulheres com distúrbios hipertensivos. Destas, 5 morreram e foram obviamente excluídas do grupo final do potencial evento adverso. link2 Foram observados 867 casos com critérios de morbidade materna que não caracterizavam potencial evento adverso. Nesse período, houve 4.617 nascidos vivos (NVs) na instituição estudada. CONCLUSãO  Na população com morbidade grave/potencial evento adversomaterno, a presença de complicações hipertensivas é prevalente, constituindo fator de risco para o binômio materno-fetal.in English, Portuguese OBJETIVO  Determinar a prevalência de intervalo inadequado de nascimento e seus fatores associados no estudo BRISA. MéTODOS  Estudo transversal com dados da coorte BRISA. O intervalo de nascimento foi categorizado em “adequado” (≥ 2 anos ou  less then  5 anos entre os nascimentos), “intervalo curto” ( less then 2 anos) e “intervalo longo” (≥ 5 anos). A análise dos fatores associados aos intervalos de nascimento curtos e longos utilizou regressão logística multinomial. RESULTADOS  A prevalência de intervalos adequados de nascimento foi de 48,3%, longa de 34,6% e curta de 17,1%. A cor da pele, idade, escolaridade, status econômico, tipo de parto, número de consultas pré-natais, paridade, pressão arterial, diabetes e anemia (valor-p  less then  0,2 na análise univariada) prosseguiram para o modelo final. A variável ≥ 3 nascimentos (odds ratio [OR] = 1,29; intervalo de confiança [IC] 1,01–1,65) esteve associada a intervalos curtos. Idade  less then  20 anos (OR = 0.48; CI 0.02–0.12) ou ≥ 35 anos (OR = 2.43; CI 1.82–3.25), ≥ 6 consultas pré-natais (OR = 0.58; CI 0.47–0.72), ≥ 3 nascimentos (OR = 0.59; CI 0.49–0.73), e diabetes gestacional (OR = 0.38; CI 0.20–0.75) foram associados a longos intervalos. CONCLUSãO  As mães mais velhas apresentaram maior probabilidade de ter longos intervalos de nascimento, e uma paridade maior aumenta as chances de intervalos curtos de nascimento. Além disso, o diabetes gestacional e o pré-natal adequado apresentaram maiores chances de ter um intervalo adequado ao nascimento, indicando que a assistência à saúde durante a gravidez é importante para incentivar um intervalo adequado entre as gestações.in English, German Mit der Reflexologie entstand in den ersten drei Jahrzehnten des 20. Jahrhunderts in Russland ein eigenständiges, Universalität beanspruchendes Konzept, welches sowohl psychische Störungen, psychisches Normalerleben als auch massenpsychologische Phänomene erklären sollte. Es beeinflusste den Behaviorismus und war wie jener eine Antwort auf die Suche nach einer objektiven Methode der Untersuchung psychischer Vorgänge. Wichtige Protagonisten waren Vladimir Michajlovič Bechterev und Naum Efimovič Išlondskij (Ischlondsky), deren Schriften internationale Verbreitung fanden.Calcium homeostasis is maintained by the actions of the parathyroid glands, which release parathyroid hormone into the systemic circulation as necessary to maintain the serum calcium concentration within a tight physiologic range. Excessive secretion of parathyroid hormone from one or more neoplastic parathyroid glands, however, causes the metabolic disease primary hyperparathyroidism (HPT) typically associated with hypercalcemia. Although the majority of cases of HPT are sporadic, it can present in the context of a familial syndrome. Mutations in the tumor suppressor genes discovered by the study of such families are now recognized to be pathogenic for many sporadic parathyroid tumors. Inherited and somatic mutations of proto-oncogenes causing parathyroid neoplasia are also known. Future investigation of somatic changes in parathyroid tumor DNA and the study of kindreds with HPT yet lacking germline mutation in the set of genes known to predispose to HPT represent two avenues likely to unmask additional novel genes relevant to parathyroid neoplasia. © Georg Thieme Verlag KG Stuttgart · New York.Primary aldosteronism (PA) is the most common cause of secondary hypertension. The hallmark of PA is adrenal production of aldosterone under suppressed renin conditions. PA subtypes include adrenal unilateral and bilateral hyperaldosteronism. Considerable progress has been made in defining the role for somatic gene mutations in aldosterone-producing adenomas (APA) as the primary cause of unilateral PA. This includes the use of next-generation sequencing (NGS) to define recurrent somatic mutations in APA that disrupt calcium signaling, increase aldosterone synthase (CYP11B2) expression, and aldosterone production. The use of CYP11B2 immunohistochemistry on adrenal glands from normal subjects, patients with unilateral and bilateral PA has allowed the identification of CYP11B2-positive cell foci, termed aldosterone-producing cell clusters (APCC). APCC lie beneath the adrenal capsule and like APA, many APCC harbor somatic gene mutations known to increase aldosterone production. These findings suggest that APCC may play a role in pathologic progression of PA. Herein, we provide an update on recent research directed at characterizing APCC and also discuss the unanswered questions related to the role of APCC in PA. © Georg Thieme Verlag KG Stuttgart · New York.OBJECTIVES  We evaluated whether differences exist among the canal flare index (CFI) values obtained by different calculation methods in the veterinary literature. STUDY DESIGN  The endosteal widths were measured from radiographic images of canine cadaveric femora. Three different formulae were used to calculate the CFI. The CFILT-M was the ratio of endosteal width at the medial aspect of the lesser trochanter (LT) to the midshaft (M), while the CFILT-I was the ratio of LT to the isthmus (I). The CFIPLT-I was the ratio of endosteal width at the proximal aspect of the lesser trochanter (PLT) and the I. The widths at each level and the CFI calculation methods were compared. Using Rashmir-Raven's method, the femora were typed as stovepipe, normal and champagne fluted. The limits of agreement were also evaluated. RESULTS  The endosteal width at the proximal aspect of the lesser trochanter was 12% wider than at the medial aspect and 8% wider at the midshaft than at the isthmus. The CFILT-M was less than CFILT-I and CFIPLT-I by 9 and 20%, respectively. By Rashmir-Raven's classification, the CFILT-M method provided 18% stovepipe, 79% normal and 3% champagne fluted femora. The CFILT-I method showed the stovepipe, the normal and the champagne fluted as 6, 82 and 12%, respectively. The CFIPLT-I method classified the femora either normal (55%) or champagne fluted (45%). The comparison of CFILT-M with the other methods using Bland-Altman analysis showed lower mean difference for the CFILT-I than the CFIPLT-I. CONCLUSION  The level of width measurements at proximal femora might have an impact on the CFI values, likewise, preoperative planning procedures and the selection of a stem type in total hip arthroplasty. Georg Thieme Verlag KG Stuttgart · New York.in English, German HINTERGRUND  Referenzwerte können zu einer Verbesserung der Standardisierung, der Untersucherunabhängigkeit und damit einer Verbesserung der Vergleichbarkeit zwischen verschiedenen Untersuchungen führen. Für die renale Mercaptoacetyltriglycin (MAG3)-Szintigrafie hat die Festlegung solcher Werte trotz der überzeugenden Vorteile jedoch nicht den Weg in die klinische Routine gefunden. ZIEL  Ziel war es, Referenzwerte für die entscheidenden quantitativen Parameter der MAG3-Nierenszintigrafie festzulegen. Die Referenzwerte sollen dazu beitragen, die Interpretation der Untersuchungsergebnisse im klinischen Alltag zu verbessern und zu erleichtern. METHODE  Wir werteten retrospektiv alle MAG3-Nierenszintigrafien aus, die in der Klinik für Nuklearmedizin des Universitätsklinikums Marburg zwischen 01/2014 und 08/2017 durchgeführt wurden. Die Gesamtstichprobe der nichtpathologisch veränderten Nierenszintigrafien umfasste 247 Patienten im Alter zwischen 25 Tagen und 88 Jahren. Alle Untersuchungen wurdesch integrierbar und versprechen eine vereinfachte und verbesserte Interpretation der MAG3-Szintigrafie.The world health organization reports that 80% of the population living within the developing countries depends basically on traditional medicine for his or her primary health care. Quite half the entire world's population still depends entirely on plants for medicines, and plants provides the active ingredients to the most traditional medical products. Hamelia patens that belong to the family Rubiaceae, is mainly found in tropical and sub-tropical areas. It is used in folk medicine against a wide range of diseases such as athlete's foot, skin problems, insect sting, psychiatric disorder, rheumatism, headache, asthma, dysentery, menses, ovarian and uterine disorders. Hamelia consists of an important bioactive constituent such as oxindole alkaloids, flavonoids, and phenolic content. Due to the presence of chlorogenic acid and epicatechin constituent in the methanolic extract of Hamelia patens, there is a noticeable anti-hyperglycemic activity as well as it possesses antioxidant activity. Acute and sub-acute toxicity study has been performed on Hamelia patens which shows that it is safe and can be used for humans. Against fungi and bacteria, the ethanol leaf extract of Hamelia has a maximum inhibitory effect. link3 The plant has various therapeutic effects like anti-inflammatory, analgesic, anti-diarrheal, anthelmintic, antidepressant, hepatoprotective, antiurolithiatic, diuretic, wound healing, and many others. In this article, we have discussed chemical constituent, pharmacological activity and traditional use of Hamelia patens. © Georg Thieme Verlag KG Stuttgart · New York.