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Lavage cytology is a method to detect cancer cells released within the abdominal cavity. It has been widely utilized, particularly for gastric cancer. However, its clinical significance has not yet been determined in colorectal cancer.

This study aimed to investigate the frequency of lavage cytology positivity and its influence on the prognosis of colorectal cancer patients.

This was a single-institution retrospective observational study.

The study was conducted at a comprehensive cancer center.

We retrospectively analyzed 3,135 colorectal cancer cases from 2007 to 2013 at our institution. Intraoperative peritoneal washing cytology was performed just after the start of the operation. Fluids were centrifuged for 5 min at 2,500 rpm, cell pellets were smeared on microscope glass slides, and Papanicolaou staining was performed.

The primary outcome was the 5-year overall survival rates. The secondary outcome was the 5-year recurrence rates.

Lavage cytology positivity was detected in 19 (2.0%) and 86 Video Abstract at http//links.lww.com/DCR/B770.

There is a paucity of evidence pertaining to long-term survival outcomes of laparoscopic versus open surgery for locally advanced rectal cancer.

This study aimed to evaluate the long-term survival outcomes of laparoscopic surgery for locally advanced rectal cancer and to investigate the recurrence pattern.

This was a prospective analysis of a registered cohort.

This study was conducted at 69 institutions across Japan.

A total of 1500 patients with clinical stage II-III rectal cancer located below the peritoneal reflection between January 2010 and December 2011 were included. After propensity score matching, all eligible patients, including the matched patients registered in 2014, were prospectively followed up.

Five-year relapse-free survival was the primary outcome.

The median follow-up period was 5.6 years. Among the 964 matched patients, the 5-year relapse-free survival was 65.1% in the open group versus 63.5% in the laparoscopic group (hazard ratio 1.04; p = 0.71). Distant recurrences at rar safely performed in terms of long-term prognosis. In addition, salvage surgery for recurrent lesions was associated with prolonged post-recurrence survival, both in patients with local and distant recurrence. However, recurrence at rare sites may require further investigation. See Video Abstract at http//links.lww.com/DCR/B793.

Lateral pelvic lymph node dissection for rectal cancer is challenging due to the complexity of the pelvic wall anatomy, and incomplete lateral pelvic lymph node dissection may result in local recurrence in the lateral pelvis. Although three-dimensional printed organ models are useful for understanding spatial anatomy, it currently remains unclear whether they improve surgical outcomes.

We aimed to assess whether the surgical effectiveness of lateral pelvic lymph node dissection is increased by the use of individualized three-dimensional printed pelvic models.

This was a retrospective study using a propensity matching analysis.

This study was conducted at a university hospital in Japan.

In total, 115 patients comprising 184 pelvic sides (right, 85 sides; left, 99 sides) who underwent lateral pelvic lymph node dissection for colorectal adenocarcinoma between January 2012 and December 2019 were enrolled.

We compared surgical outcomes using three-dimensional printed pelvic models with control outcomesduring lateral pelvic lymph node dissection. This result suggests that three-dimensional printed models help surgeons to complete more detailed procedures. See Video Abstract at http//links.lww.com/DCR/B776.

The present study demonstrated that by referring to individualized three-dimensional printed pelvic models, colorectal surgeons harvested a larger number of lateral pelvic lymph nodes during lateral pelvic lymph node dissection. This result suggests that three-dimensional printed models help surgeons to complete more detailed procedures. See Video Abstract at http//links.lww.com/DCR/B776.

In selected patients with peritoneal metastases of colorectal origin, complete cytoreduction has been the main single prognostic factor influencing long-term outcomes. In these patients, indocyanine green fluorescence imaging seems to be useful in detecting small subclinical peritoneal implants. However, quantitative fluorescence analysis has not yet been established as standard.

This study aimed to evaluate the sensitivity and specificity of quantitative indocyanine green fluorescence assessment in the detection of peritoneal metastases of nonmucinous colorectal origin.

This is a single-center, single-arm, low-intervention prospective trial.

A fluorescence assessment device was used for intraoperative fluorescence quantitative assessment.

Consecutive patients diagnosed with peritoneal metastases of colorectal origin who met the inclusion criteria were selected for curative surgery.

Intravenous indocyanine green was administered 12 hours before surgery. Cytoreduction was performed through nodule iógica y la excreción de verde de indocianina pueden interferir con la evaluación de implantes inadvertidos en la serosa intestinal y el hígado.CONCLUSIONESLa cuantificación del verde de indocianina, parece ser útil en la evaluación de metástasis peritonea-les colorrectales no mucinosas. La captación de fluorescencia por encima de 181 unidades parece correlacionarse con la malignidad, mientras que la captación por debajo de 100 unidades parece co-rrelacionarse con una patología benigna. Consulte Video Resumen en http//links.lww.com/DCR/B743. (Traducción - Dr. Fidel Ruiz Healy).

Endoscopic vacuum therapy for the treatment of rectal anastomotic leak has been shown to be effective and safe. The majority of patients are treated after fecal diversion to avoid further septic complications.

To report the effectiveness of endoscopic vacuum therapy for rectal anastomotic leak without diversion compared to secondary stoma creation.

Retrospective cohort analysis.

University hospital, single-center.

Patients undergoing sigmoid or rectal resection without fecal diversion during primary surgery who were treated with endoscopic vacuum therapy for clinically relevant anastomotic leak.

Treatment success (sepsis control, granulation and closure of the leak cavity, and no subsequent interventional or surgical procedure required); treatment duration; complications associated with endoscopic vacuum therapy; outpatient treatment; and restoration of intestinal continuity in diverted patients.

Fifty-seven patients were included. In 20 patients (35%), endoscopic vacuum therapy was initiated win con respecto al control de la sepsis, granulación de la cavidad de la fuga, como se evitó la cirugía y la sobrevida sin ostomía a largo plazo. Consulte Video Resumen en http//links.lww.com/DCR/B737. (Traducción-Dr. Xavier Delgadillo).

Postoperative benign anastomotic stricture is associated with colorectal anastomosis following surgery for colorectal cancer. Endoscopic stricturotomy is a novel technique that has been demonstrated to be safe and effective for the treatment of colorectal anastomotic stricture in several case reports or series.

We designed this study to investigate the efficacy of endoscopic stricturotomy for postoperative benign anastomotic stricture in patients for colorectal cancer. The primary outcome were stricture-recurrence free survival and re-operation-free survival.

This is a retrospective study.

This study presents a single-center experience.

This retrospective study included patients with colorectal cancer who underwent surgical resection and developed anastomotic stricture between January 2014 and June 2019 and treated with endoscopic stricturotomy.

Immediate technical success of and endoscopic stricturotomy, the factors associated with the success and recurrence.

Endoscopic stricturotomy was perforat http//links.lww.com/DCR/B739 .

Endoscopic stricturotomy is a safe and effective technique for postoperative benign anastomotic stricture. However, if the length of the stricture is ≥1 cm, endoscopic stricturotomy may not be effective and recurrence of postoperative benign anastomotic stricture is also likely. See Video Abstract at http//links.lww.com/DCR/B739 .

The low lymphocyte-to-monocyte ratio and high platelet-to-lymphocyte ratio have been reported to be poor prognostic indicators in various solid tumors, but the prognostic significance in rectal cancer remains controversial.

We sought to determine the prognostic value of the lymphocyte-to-monocyte ratio and the platelet-to-lymphocyte ratio following curative-intent surgery for rectal cancer.

Following PRISMA guidelines (PROSPERO, ID CRD42020190880), PubMed and Embase databases were searched through January 2021 including 3 other registered medical databases.

Studies evaluating the impact of pretreatment lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio on overall or disease-free survival in patients undergoing curative rectal cancer resection were selected.

The main outcome measures were overall and disease-free survival.

A total of 23 studies (6683 patients) were included; lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio were evaluated in 14 and 16 studies. A low lymphocytally represents a simple and reliable biomarker that could help optimize individualized clinical decision-making in high-risk patients.

https//www.crd.york.ac.uk/prospero/; ID CRD42020190880.

https//www.crd.york.ac.uk/prospero/; ID CRD42020190880.

Stigma and uncertainty are noticed in global pandemics. Their impacts on health care providers tend to persist notably during and after the outbreaks. Our objective was to assess stigma, uncertainty, and coping among health care providers through an online survey using the Discrimination and Stigma Scale Version 12 (DISC-12) modified version to assess stigma related to treating COVID-19, the Intolerance of Uncertainty Scale, and the Brief Resilient Coping Scale (BRCS). Of the respondents (n = 65), 63.1% treated patients with COVID-19, and 21.5% worked in isolation hospitals. Physicians who treated patients with COVID-19 had significantly higher scores in all DISC subscales unfair treatment (8.73 ± 6.39, p = 0.001), stopping self from doing things (2.05 ± 1.41, p = 0.019), overcoming stigma (1.17 ± 0.80, p = 0.035), and positive treatment (1.90 ± 1.65, p = 0.005). Unfair treatment was negatively correlated with BRCS (r = -0.279, p = 0.024). HDAC inhibitor On the other hand, physicians who did not treat patients with COVID-= 0.005). Unfair treatment was negatively correlated with BRCS (r = -0.279, p = 0.024). On the other hand, physicians who did not treat patients with COVID-19 had significantly higher BRCS scores. We concluded that frontline physicians experienced greater stigma associated with lower resilient coping strategies.Abstract.

To determine the prevalence of anterior vitreous detachment (AVD) in routine bag-in-the-lens cataract cases and whether we could identify risk factors for its presence.

University Hospital of Antwerp, Belgium.

Prospective cross sectional study.

Patients having routine bag-in-the-lens cataract surgery were included. Patients with traumatic cataract, prior intra-ocular surgeries, YAG-laser, intravitreal injection or medical conditions that might affect normal ophthalmologic anatomy were excluded. Several parameters were collected from the patients records and their surgical videos/photos/OCT were evaluated.

99 Eyes of 99 patients were included. Detectable AVD was observed in 62 eyes (63%). AVD was not present in 37 eyes (37%). The difference in prevalence of AVD between males and females was not statistically significant (P = 0. 55, Pearson Chi Square test). The Mann Whitney U test for axial length was not statistically significant (P = 0. 38). The Mann Whitney U test for age was statistically significant (P < 0.