Flowersburnett3079

These incidents may also result in a radiation-combined injury (RCI); a chemical, thermal, or traumatic injury, with radiation exposure. Skin injuries from medical diagnostic and therapeutic imaging, medical misadministration of nuclear medicine or radiotherapy, occupational exposures (including research) to radioactive sources are more common but are not the focus of this manuscript. Diagnosis and evaluation of injuries are based on the scenario, clinical picture, and dosimetry, and may be assisted through advanced imaging techniques. Research-based multidisciplinary therapies, both in the laboratory and clinical trial environments, hold promise for future medical management. Great progress is being made in recognizing the extent of injuries, understanding their pathophysiology, as well as diagnosis and management; however, research gaps still exist.Telomerase plays an important role in maintaining the length of telomere during cell division and is recognized as a new kind of biomarkers for cancer diagnosis. In this work, we present a brand new telomerase detection strategy based on a DNA points accumulation for imaging in nanoscale topography (DNA-PAINT) like strategy. With an extraordinary spatial resolution (∼10 nm), the DNA-PAINT based strategy offers several advantages. First, it avoids complicated polymerase chain reaction and electrophoresis procedures. Second, it enables super resolution imaging of the reaction products with a high signal-to-noise ratio and facilitates the location of telomeric elongation sites on the single particle level, which results in a high sensitivity. Third, the detection scheme of the DNA-PAINT strategy allows directin situvisualization of the telomeric elongation process, which has never been achieved before. All these advantages make the DNA-PAINT telomerase detection strategy significant for dynamic investigation of telomerase related physiological processes as well as cancer diagnosis.The shift of a magnetization loop along the magnetic field axis for a ferromagnetic (FM)/anti-ferromagnetic (AFM) system when it is cooled through Néel temperature of AFM layer is called exchange anisotropy or exchange bias. Here, using micromagnetic simulations we propose that spin transfer torque (STT) mechanism would indeed be helpful in realizing the shift of the magnetization loop along magnetic field axis through domain wall resistance for an infinitely long FM nanowire without having AFM layer, which we call as spin transfer torque bias (STTB). Essentially, STTB is realized on both positive and negative magnetic field axis by varying the angle between spin polarized current and Zeeman field from 0º to 180º respectively and the origin is attributed to helical motion of the domain wall (DW). However, we do not see STTB at 90º due to coherent rotation of domain. We also ascertain that STTB is also a function of magnetic anisotropy, current density, polarization strength and non-adiabatic spin transfer torque term. Variation in STTB for different FM systems such as Fe2CoSi, Ni80Fe20 and Fe is attributed to a change in domain wall width. We believe that present results would lead to a new dimension in the field of spintronics.Electroencephalogram (EEG) recordings often contain large segments with missing signal due to poor electrode contact or other artifact contamination. Recovering missing values, contaminated segments and lost channels could be highly beneficial especially for automatic classification algorithms, such as machine/deep learning models, whose performance relies heavily on high quality data. The current study proposes a new method for recovering missing segments in EEG. In the proposed method, the reconstructed segment is estimated by substitution of missing part of the signal with the normalized weighted sum of other channels. The weighting process is based on inter-channel correlation of non-missing preceding and proceeding temporal windows. The algorithm was designed to be computationally efficient. Experimental data from patients (N = 20) undergoing general anesthesia due to elective surgery were used for the validation of the algorithm. Data were recorded using a portable EEG device with 10 channels and a self-adhesive frontal electrode during induction of anesthesia with propofol from waking state until burst suppression level, containing lots of variation in both amplitude and frequency properties. The proposed imputation technique was compared with another simple-structure technique. The distance correlation was used as a measure of comparison evaluation. The proposed method with average distance correlation of 82.48±10.01 (µ ± σ)% outperformed its competitor with average distance correlation of 67.89±14.12 (µ ± σ)% . This algorithm also showed better performance for an increasing number of missing channels. In conclusion, the proposed technique provides an easy-to-implement and computationally efficient approach for reliable reconstruction of missing or contaminated EEG segments.In previous works, we showed that incorporating individual airways as organs-at-risk (OARs) in the treatment of lung stereotactic ablative radiotherapy (SAbR) patients potentially mitigates post-SAbR radiation injury. However, the performance of common clinical dose calculation algorithms in airways has not been thoroughly studied. Airways are of particular concern because their small size and the density differences they create have the potential to hinder dose calculation accuracy. To address this gap in knowledge, here we investigate dosimetric accuracy in airways of two commonly used dose calculation algorithms, the anisotropic analytical algorithm (AAA) and Acuros-XB (AXB), recreating clinical treatment plans on a cohort of four SAbR patients. A virtual bronchoscopy software was used to delineate 856 airways on a high-resolution breath-hold CT (BHCT) image acquired for each patient. The planning target volumes (PTVs) and standard thoracic OARs were contoured on an average CT (AVG) image over the breathing cycle. Conformal and intensity-modulated radiation therapy plans were recreated on the BHCT image and on the AVG image, for a total of four plan types per patient. Dose calculations were performed using AAA and AXB, and the differences in maximum and mean dose in each structure were calculated. The median differences in maximum dose among all airways were ≤0.3Gy in magnitude for all four plan types. With airways grouped by dose-to-structure or diameter, median dose differences were still ≤0.5Gy in magnitude, with no clear dependence on airway size. These results, along with our previous airway radiosensitivity works, suggest that dose differences between AAA and AXB correspond to an airway collapse variation ≤0.7% in magnitude. This variation in airway injury risk can be considered as not clinically relevant, and the use of either AAA or AXB is therefore appropriate when including patient airways as individual OARs so as to reduce risk of radiation-induced lung toxicity.Hexagonal BCN (h-BCN) is considered to be a promising dielectric ceramic material with a hybrid B-C-N structure and an electromagnetic wave (EMW) absorbing material with tunable properties. H-BCN bulk and microtube architectures are simultaneously synthesized by precursor pyrolysis method using BCl3, aniline (AN) and diethylenetriamine (DETA) as the raw material. By analyzing its electromagnetic parameters, the effective absorption bandwidth of the sample cracking at 900 ℃ with the proportion of raw materials (DETA AN=11) can be up to 7.2 GHz, and the minimum reflection loss (RL) can reach -43.6 dB at 7.92 GHz with a thickness of 3.5 mm. Moreover, the EMW absorbing property of the ceramic can be tuned by adjusting the ratio of monomers, pyrolysis temperature, and cooling rates.In this paper, we study the reversible electroporation process on normal and cancerous cervical cells. The 2D contour of the cervical cells is extracted using image processing techniques from the Pap smear images. The conductivity change in the cancer cell model has been used to differentiate the effects of the high-frequency electric field on normal and cancerous cells. The cells' dielectric constant modulates when this high-frequency pulse is applied based on the Debye relaxation. To computationally visualize the effects of the electroporation on the cell membrane, the Smoluchowski equation is employed to estimate pore density, and Maxwell equations are used to determine the electric potential developed across the membrane of the cervical cell. The results demonstrate the suitability of this mathematical model for studying the response of normal and cancerous cells under electric stress. The electric field is supplied with the help of a realistic pulse generator which is designed on the principle of Marx circuit and avalanche transistor-based operations to produce a Gaussian pulse. The paper here uses a strength-duration curve to differentiate the electric field and time in nanoseconds required to electroporate normal and cancerous cells.The van der Waals ferromagnetic material VI3is a magnetic Mott insulator. In this work, we investigate the effects of isotropic and anisotropic pressure on the atomic structure and the electronic structure of VI3using the first-principles method. The in-plane strain induces structural distortion and breaks the three-fold rotational symmetry of the lattice. Both the in-plane and out-of-plane strain widen the conduction and the valence bands, reduce the energy band gap and drive VI3from a semiconductor to a three-dimensional metal. The structural distortion is not the cause of insulator-to-metal transition. Calculations of the magnetocrystalline anisotropy energy indicate an easy-axis to easy-plane transition when the pressure is higher than 2 GPa. find more The ferromagnetic Curie temperature falls from 63 K at 0 GPa to 25 K at 6 GPa.One of the key functions of a clinical nursing faculty is selecting patient assignments for undergraduate nursing students in the clinical setting. However, there is limited existence of evidence or strong scholarship that informs clinical nursing faculty on this specific process. In particular, they are left wondering regarding the factors, variables and methods that can be considered in this process. Hence, an integrative literature review was conducted that addressed the following questions What is the current state of evidence and what are the best practices in selecting patient assignments for undergraduate nursing students in the clinical setting? What factors and variables do clinical nursing faculty consider in this process? A total of nine documents and two chapters from clinical nursing education books met the inclusion criteria for this literature review. The factors identified from the literature review considered in the patient selection process were (a) needs of the patients and their families, (b) nursing students' learning needs and characteristics, (c) course objectives, (d) knowledge of the clinical faculty in clinical teaching, and (e) the learning environment. With respect to the methods of patient selection, three methods were also identified from the literature review (a) faculty-led, (b) student-directed and (c) shared approach. The findings of this review indicate that further research is needed to better understand other factors and variables that may influence the patient selection process in the clinical learning environment. More qualitative studies are recommended to provide a more in-depth understanding about the processes, relationships, methods, assumptions, biases and behaviors involved regarding this topic in clinical nursing education.