Finnegandueholm0022
We evaluated soft-tissue thickness changes after bimaxillary surgery according to vertical facial patterns in patients with skeletal Class III malocclusion with mandibular prognathism.
Forty-three Korean patients (16 men and 27 women; mean age, 22.6±4.1years) with skeletal Class III malocclusion who underwent bimaxillary surgery were divided into 2 groups normal-angle group (N group) and high-angle group (H group), on the basis of the presurgical angle of the mandibular plane relative to the sella-nasion plane (SN-MP). Changes in hard-tissue landmarks and soft-tissue thickness before and after surgery were analyzed from reconstructed 3-dimensional cone-beam computed tomography images. Postoperative soft-tissue thickness in both groups was compared with that in 40 patients with normal skeletal Class I malocclusion in the reference group.
Group N (27°-37°) and group H (>37°) did not differ significantly in terms of sex and age before surgery. Preoperative pogonion (Pog) thickness was significantly less in group H (9.7±1.6mm) than in group N (10.8±1.9mm)(P=0.042). Adjusted multiple linear regression analysis showed a weak positive linear relationship between the SN-MP before surgery and soft-tissue Pog thickness change (R
of 0.361; P=0.001) after surgery, but the area below the lower lips was not completely normalized despite surgery.
The thickness of the soft-tissue Pog may increase slightly after surgery in patients with skeletal Class III malocclusion with a higher preoperative mandibular plane angle, but normalization in the area cannot be completely achieved despite surgery.
The thickness of the soft-tissue Pog may increase slightly after surgery in patients with skeletal Class III malocclusion with a higher preoperative mandibular plane angle, but normalization in the area cannot be completely achieved despite surgery.
Although the major limitation to exercise performance in patients with COPD is dynamic hyperinflation (DH), little is known about its relation with cardiac response to exercise. Our objectives were to compare the exercise response of stroke volume (SV) and cardiac output (CO) between COPD patients with or without DH and control subjects, and to assess the main determinants.
Fifty-seven stable COPD patients without cardiac comorbidity and 25 healthy subjects were recruited. Clinical evaluation, baseline function tests, computed tomography and echocardiography were conducted in all subjects. Patients performed consecutive incremental exercise tests with measurement of operating lung volumes and non-invasive measurement of SV, CO and oxygen uptake (VO
) by an inert gas rebreathing method. Biomarkers of systemic inflammation and oxidative stress, tissue damage/repair, cardiac involvement and airway inflammation were measured.
COPD patients showed a lower SV/VO
slope than control subjects, while CO response was compensated by a higher heart rate increase. COPD patients with DH experienced a reduction of SV/VO
and CO/VO
compared to those without DH. In COPD patients, the end-expiratory lung volume (EELV) increase was related to SV/VO
and CO/VO
slopes, and it was the only independent predictor of cardiac response to exercise. However, in the regression models without EELV, plasma IL-1β and high-sensitivity cardiac troponin T were also retained as independent predictors of SV/VO
slope.
Dynamic hyperinflation decreases the cardiac response to exercise of COPD patients. This effect is related to systemic inflammation and myocardial stress but not with left ventricle diastolic dysfunction.
Dynamic hyperinflation decreases the cardiac response to exercise of COPD patients. This effect is related to systemic inflammation and myocardial stress but not with left ventricle diastolic dysfunction.Individuals with substance use disorders (SUDs), including those in long-term recovery, and their loved ones are facing rapid changes to treatment and support services due to COVID-19. To assess these changes, the Addiction Policy Forum fielded a survey to their associated patient and family networks between April 27 and May 13, 2020. Individuals who reported a history of use of multiple substances were more likely to report that COVID-19 has affected their treatment and service access, and were specifically more likely to report both use of telehealth services and difficulties accessing needed services. These findings suggest that individuals with a history of using multiple substances may be at greater risk for poor outcomes due to COVID-19, even in the face of expansion of telehealth service access.Adolescents and young adults (AYA) with substance use disorders (SUD) have low rates of engagement and retention in SUD treatment (Mericle et al., 2015). Engagement and retention refers to treatment attendance and regular communication with providers. The reason for this low rate is multifactorial and includes the stigma surrounding SUD and treatment (Bagley, Hadland, Carney, & Saitz, 2017), and challenges accessing developmentally appropriate treatment (Mericle et al., 2015; Sterling, Weisner, Hinman, & Parthasarathy, 2010). Yet engaging AYA early in their trajectory of substance use offers an invaluable opportunity to minimize the short-term and long-term consequences of use (Compton et al., 2019; Levy, Williams, & Prevention, C. on S. selleck compound U. A., 2016). As specialists in pediatric addiction, we made significant changes in how we provide care for youth in treatment due to the COVID-19 pandemic. In the following commentary, we discuss the potential positive and negative impacts of those changes and suggestions for future research.The phytoremediation of cadmium (Cd) and pyrene (PYR) in agricultural soil with willow was investigated by carrying out a pot-culture experiment in a greenhouse. The soil was incubated with urea 60 days before it was used for this experiment. The concentrations of Cd and PYR in soil and willow, the bioconcentration and transfer factors, the physiological and biochemical responses, and plant biomass production were determined at the end of the experiment. The phytoremediation with willow based on urea application was effective for enhancing the phytoremediation of Cd and PYR contaminated soil. Urea application did not affect the available Cd but increased the accumulation of soil Cd and the plant biomass of different parts of the willow. The removal rate (77.1-89.5%) of PYR in soil was not significantly affected although urea application decreased the accumulation of PYR in willow root and bark. Urea application significantly promoted the uptake of chlorophyll, carotenoid and malondialdehyde by willow leaves. The results of this study will provide scientific information for the effective phytoremediation of Cd in Cd and PYR contaminated soil.Natural attenuation in acid mine drainage (AMD) due to biological iron and arsenic oxidation offers a promising strategy to treat As-rich AMD in passive bioreactors. A reactive transport model is developed in order to identify the main controlling factors. It simulates batch and flow-through experiments that reproduce natural attenuation in a high-As AMD. The 2-D model couples second-order microbial kinetics (Fe- and As- oxidation) and geochemical reactions to hydrodynamic transport. Oxidation only occurrs in the biofilm with an oxygen transfer from the air through the water column. The model correctly simulates the Fe(II)-Fe(III) and As(III)-As(V) concentrations in the outlet waters and the precipitates, over hydraulic retention times from 30 min to 800 min. It confirms that the natural attenuation at 20 °C is driven by the fast Fe(II) oxidation and slow As(III) oxidation that favors arsenite trapping by schwertmannite over amorphous ferric arsenate (AFA) formation. The localization of iron oxidation in the biofilm limits the attenuation of arsenic and iron as the water column height increases. The change in the composition of the bacterial iron-oxidizer community of the biofilm at the lowest pH boundary seems to control the Fe(II) oxidation kinetic rate besides the bacterial concentration.Arsenic (As) and uranium (U) are naturally occurring trace elements with potentially adverse effects on human health. This work revisits nine case studies on As/U accumulation and remobilization mechanisms in aquifers with different geological and stratigraphical backgrounds to develop a systematic overview of Germany's geogenic inventory of these trace elements. It uses geochemical proxies for a total of 270 solid samples to explain their spatio-temporal distribution while Pleistocene geological development can explain their extensive absence in sediments and related groundwater in northern Germany, their abundance and distribution in the central and southern parts are widely controlled by sediment provenance geochemistry. Only highly felsic origin (Moldanubian Variscides) enables creation of elevated U in the systems while lower degrees of provenance felsicity (Rhenohercynian Variscides) appear to be sufficient for As presence. Postdepositional (hydro)geological and anthropogenically triggered intra-basinal processes of trace element accumulation, redistribution and eventually remobilization to groundwater contribute to the present-day situation. Therefore, the ultimate control of these incompatible trace elements is magmatic, even in old sedimentary systems, and still clearly traceable in nowadays large-scale geogenic As and U distribution in Germany and probably elsewhere.The co-occurrence of microplastics/nanoplastics (MPs/NPs) with other environmental contaminants has stimulated a focus shift of its skyrocketed research publications (more than 3000 papers during 2016-2020, Web of Science) from ubiquitous occurrence to interactive toxicity. Here, in this review, we provided the current state of knowledge on toxicological interaction of MPs/NPs with co-contaminants (heavy metals, polycyclic aromatic hydrocarbons, pharmaceuticals, pesticides, nanoparticles, organohalogens, plastic additives, and organotins). We discussed the possible interactions (aggregation, adsorption, accumulation, transformation, desorption) that played a role in influencing the toxicity of the mixture. Besides, the type of interactions such as synergistic, antagonistic, potentiating was expounded to get a deeper mechanistic understanding. Despite the wide occurrence and usage, scant studies were available on polypropylene, polyethylene terephthalate. Our analysis shows a dearth of research on common occurring heavy metals (mercury, lead, chromium), phthalates, personal care products. link2 Considerations for environmental factors such as the presence of dissolved organic matter, pH, salinity, temperature, and effects of different colors and types of polymer are recommended.Microbial Fuel Cell (MFC) can degrade the organic matter (OM) in wastewater at the anode and transfer electrons to the cathode. In this work, the harmful NOX gas was used as electron acceptor in MFC and converted to harmless N2. The OM in water was indirectly used as a zero-cost reducing agent for NOx removal. More than 80% of NOX was removed continuously by MFC at room temperature. The NOX was directly reduced to N2 at MFC cathode and the cathode activity played a key role on enhancing the NOX removal. The NOX removal efficiency by the cathode of high potential was 1.37 times that by the cathode of low potential. When O2 coexisting with NO as the electron acceptor, not only the NOX removal but also the power output of MFC was improved greatly. The presence of NOX did not decrease the power generation of MFC under the same O2 concentration. The MFCs showed good stability for NOX treatment and power output. link3 Moreover, the possible pathways and advantages of NOX removal by MFC were discussed in detail. These results indicated that the MFC system has the potential to treat wastewater, purify flue gas and recover energy simultaneously.
