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202) and remained stable until the end of follow-up. The CVI increased at 1 and 3 months postoperatively (P = 0.001 and 0.005, respectively).

The choroid thickened in the early postoperative period. The compression force of the buckle implant might disturb microcirculatory drainage and contribute to the thickening. The choroid spontaneously recovered to the preoperative level over time.

The choroid thickened in the early postoperative period. The compression force of the buckle implant might disturb microcirculatory drainage and contribute to the thickening. The choroid spontaneously recovered to the preoperative level over time.

To investigate the role of type 2 macular neovascularization with subsequent subretinal fibrosis in the pathogenesis of outer retinal tubulation (ORT).

We conducted a retrospective cohort study of patients with stabilized inactive exudative macular degeneration who had been treated with intravitreal injections of anti VEGF agents. Baseline fluorescein and OCT images were included. MNVs were classified by type and size. learn more Consecutive OCT images analysed for ORT development.

144 eyes of 134 patients were included in this study. Sixty eyes presented with pure type 1 MNV. Eighty four eyes presented with some type 2 component to MNV. In total, evidence of ORT is shown in 55 (38%) eyes. In the Type-1 group, 6.7% developed ORT. ORT developed in 61% of eyes with some Type-2 component to the MNV. Among eyes that developed ORT, 92.7% presented with some Type-2 component. In a multivariate analysis, type-2 membranes on OCT (22.2 [6.1-80.8]; P<0.001), larger MNV size (>1DA(5.1 [1.1-24.2]; P=0.041) and >1.5DA (9.0 [1.8-44.0]; P=0.007), and presence of subretinal fibrovascular material (3.1 [1.1 - 8.5]; P=< 0.03), are associated with higher odds of ORT formation. Once the ORT is formed, fibrosis was observed directly underlying the ORT on SD-OCT in 70.9% of cases.

Type-2 membranes at presentation predicts ORT formation. Fibrosis often underlies ORT. This suggests contraction of type-2 MNV derived fibrosis may be important in ORT formation.

Type-2 membranes at presentation predicts ORT formation. Fibrosis often underlies ORT. This suggests contraction of type-2 MNV derived fibrosis may be important in ORT formation.

To discuss a case of a macular hole formation after vitrectomy for myopic retinoschisis with foveal detachment and spontaneous closure, during long term follow-up.

Case report.

A 71-year-old man with myopic retinoschisis with foveal detachment had a vitrectomy with internal limiting membrane (ILM) peeling combined with cataract surgery in the left eye. The preoperative best-corrected visual acuity (BCVA) was 8/20, and the axial length was 27.11 mm. A macular hole with foveal detachment was observed 1 month after surgery. However, the macular hole closed spontaneously with foveal detachment at 4 months of follow-up. Foveal detachment resolved and BCVA improved to 20/20 at nine months of follow-up.

This case suggests that the macular hole formed after vitrectomy for myopic retinoschisis with foveal detachment with ILM peeling can close spontaneously.

This case suggests that the macular hole formed after vitrectomy for myopic retinoschisis with foveal detachment with ILM peeling can close spontaneously.

To report the case of a patient presenting with newly diagnosed atypical hemolytic uremic syndrome (aHUS) and Purtscher-like retinopathy.

Observational case report and review of literature.

A 38-year-old female presented with 3 months of rashes, fevers, arthralgias, and abdominal pain. Initial workup was suggestive of hypereosinophilic syndrome or adult-onset Still's disease. The patient developed acute renal failure and progressively blurry vision bilaterally over the course of 5 days. Funduscopic exam was notable for numerous Purtscher flecken and cotton-wool spots, with rare intraretinal hemorrhages at the posterior pole. The constellation of renal failure, hemolytic anemia, and thrombocytopenia prompted a work-up for thrombotic microangiopathy that was remarkable for a mutation in the gene coding for complement protein C9.

The patient was diagnosed with aHUS. The patient was treated with intravenous pulse dose steroids for 3 days and an extended course of eculizumab. The patient's renal failure resolved, and her visual acuity improved, though she had residual visual field constriction and developed bilateral optic atrophy. Outcomes of other cases of Purtscher-like retinopathy related to aHUS are reviewed.

Purtscher-like retinopathy is a rare, but severe ophthalmic complication of aHUS. Eculizumab is an effective treatment for the systemic illness caused by aHUS, and anatomic resolution of Purtscher-like retinopathy may follow, although visual prognosis remains guarded. Recovery of visual acuity may lag behind resolution of macular edema in these patients.

Purtscher-like retinopathy is a rare, but severe ophthalmic complication of aHUS. Eculizumab is an effective treatment for the systemic illness caused by aHUS, and anatomic resolution of Purtscher-like retinopathy may follow, although visual prognosis remains guarded. Recovery of visual acuity may lag behind resolution of macular edema in these patients.

To report a case of bilateral diffuse uveal melanocytic proliferation (BDUMP) over 30 months follow-up.

Multimodal imaging including ultrawidefield color fundus photography, blue light fundus autofluorescence, swept-source optical coherence tomography, fluorescein and ICG angiography.

A 49-year old female presented with decreased vision two months after bladder cancer surgery. Exudative retinal detachment as well as leopard spot pattern chorioretinopathy was observed in the right eye. Chemotherapy and cystectomy were initiated. Progressive bilateral vision loss occurred with melanocytic proliferation, choroidal thickening, subretinal fibrosis, fluid extravasation, rapid development of mature cataract, multiple iris cysts and rubeosis despite plasmapheresis and intravenous immunoglobulins (IVIG). Following cataract surgery, massive fibrin reaction resulted in a ciliolenticular block. One year later, positron emission tomography-computed tomography (PET-CT) revealed absence of metastases. At month 23, choroidal thickness increased in line with tumor progression.